scholarly journals Fusion of airways during avian lung development constitutes a novel mechanism for the formation of continuous lumena in multicellular epithelia

2020 ◽  
Vol 249 (11) ◽  
pp. 1318-1333
Author(s):  
Michael A. Palmer ◽  
Celeste M. Nelson
Keyword(s):  
Lung Development ◽  
Avian Lung

Dexamethasone Effect on Embryonic Chick Respiratory Epithelium

1982 ◽  
Vol 40 ◽  
pp. 248-249
Author(s):  
M.R. Richter ◽  
R.V. Blystone
Keyword(s):  
Lung Development ◽  
Critical Role ◽  
Respiratory Epithelium ◽  
Chick Embryos ◽  
Embryonic Chick ◽  
White Leghorn ◽  
Lung Maturation ◽  
Synthetic Analogs ◽  
Lung Physiology ◽  
Avian Lung

Dexamethasone and other synthetic analogs of corticosteroids have been employed clinically as enhancers of lung development. The mechanism(s) by which this steroid induction of later lung maturation operates is not clear. This study reports the effect on lung epithelia of dexamethasone administered at different intervals during development. White Leghorn chick embryos were used so as to remove possible maternal and placental influences on the exogenously applied steroid. Avian lung architecture does vary from mammals; however, respiratory surfactant produced by the lung epithelia serves an equally critical role in avian lung physiology.

scholarly journals Lung elastic fibres from embryonic to adult birds

2008 ◽  
Vol 14 (S3) ◽  
pp. 113-114
Author(s):  
Ana Honório ◽  
Maria de Lurdes Pinto ◽  
Carlos Gonçalves ◽  
Vasco Bairos
Keyword(s):  
Image Analysis ◽  
Experimental Model ◽  
Analytical Methods ◽  
Lung Development ◽  
Domestic Fowl ◽  
Gallus Gallus ◽  
Elastic Fibres ◽  
Morphological Studies ◽  
Avian Lung

In mammals it is well known the role of the elastic fibres in the lung development and its fundamental importance in the process of distending and recoil of the organ as a whole. The bird's lungs are compact and virtually non-expansible.After morphological studies on elastic fibres distribution and quantification by image analysis we carried out a study on biochemical methods to quantify elastin in the avian lung, using domestic fowl (Gallus gallus) as an experimental model. We made use of two analytical methods for the elastin determination in these animal lungs from the 14th day of hatching until the 42nd day after hatchling.

Effects of hypoxia or hyperoxia on the lung of the chick embryo

1989 ◽  
Vol 67 (5) ◽  
pp. 515-519 ◽  
Author(s):  
Lijing Xu ◽  
Jacopo P. Mortola
Keyword(s):  
Chick Embryo ◽  
Lung Development ◽  
Chronic Hypoxia ◽  
Ventilatory Response ◽  
Mechanical Stretch ◽  
Mechanical Effect ◽  
Cellular Component ◽  
Chick Embryos ◽  
Breathing Cycle ◽  
Avian Lung

Newborn mammals in chronic hypoxia or hyperoxia experience, respectively, an increase or decrease in lung weight:body weight ratios, possibly because of the mechanical effect on the lung accompanying the ventilatory response. Because the avian lung does not expand or contract with the breathing cycle, we asked whether or not qualitatively similar changes could be observed in the lung of chick embryos incubated in hypoxic or hyperoxic conditions. Hypoxic embryos (10% O2, days 14–18) were smaller than controls incubated in normoxia, with higher hematocrit values and larger lung weight:body weight ratios (both wet and dry). Both the total pulmonary DNA (reflecting the cellular component) and the DNA concentration were decreased in hypoxia. Hyperoxic embryos (50% O2, days 7–18 or days 14–18) had lower hematocrit values and smaller dry lung weight:body weight ratios than controls, with similar DNA concentrations. In general, the differences from controls were more apparent in those embryos hyperoxic from day 14 to 18 of incubation than from day 7 to 18. We conclude that changes in lung weights qualitatively similar to those occurring in the chronically hypoxic or hyperoxic newborn mammal can also be observed in the hypoxic or hyperoxic chick embryo, suggesting that they are not necessarily caused by changes in mechanical stretch on the lung.Key words: lung development, lung DNA, avian growth.

The role of WNT/b-catenin signaling in smooth muscle cells during lung development and repair

Pneumologie ◽  
2014 ◽  
Vol 68 (06) ◽  
Author(s):  
A Moiseenko ◽  
E El Agha ◽  
B MacKenzie ◽  
S De Langhe ◽  
S Bellusci
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Lung Development ◽  
Muscle Cells

Disruption of mesenchymal glucocorticoid signaling attenuates embryonic lung development and results in post natal lethality in mice

2013 ◽  
pp. 1-1
Author(s):  
Rowan Hardy ◽  
Aiqing Li ◽  
Shihani Stoner ◽  
Jan Tuckermann ◽  
Markus Seibel ◽  
...  
Keyword(s):  
Lung Development ◽  
Embryonic Lung ◽  
Glucocorticoid Signaling
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