scholarly journals The various and shared roles of lncRNAs during development

2019 ◽  
Vol 248 (11) ◽  
pp. 1059-1069 ◽  
Author(s):  
Juan M. Murillo‐Maldonado ◽  
Juan R. Riesgo‐Escovar
Keyword(s):  
Author(s):  
Della Jacobsen

Responsibility for a corporate Internet programme will typically go to an individual within the information services or computer resources group. The information professional given this responsibility must have the communication skills needed to forge effective relationships between a diverse array of individuals, functional work groups, and departments. The opportunity to establish effective working relationships is realized when common goals are shared, roles are defined, information is communicated, and conflicts are resolved.


BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Daniel Restrepo-Montoya ◽  
Phillip E. McClean ◽  
Juan M. Osorno

Abstract Background Legume species are an important plant model because of their protein-rich physiology. The adaptability and productivity of legumes are limited by major biotic and abiotic stresses. Responses to these stresses directly involve plasma membrane receptor proteins known as receptor-like kinases and receptor-like proteins. Evaluating the homology relations among RLK and RLP for seven legume species, and exploring their presence among synteny blocks allow an increased understanding of evolutionary relations, physical position, and chromosomal distribution in related species and their shared roles in stress responses. Results Typically, a high proportion of RLK and RLP legume proteins belong to orthologous clusters, which is confirmed in this study, where between 66 to 90% of the RLKs and RLPs per legume species were classified in orthologous clusters. One-third of the evaluated syntenic blocks had shared RLK/RLP genes among both legumes and non-legumes. Among the legumes, between 75 and 98% of the RLK/RLP were present in syntenic blocks. The distribution of chromosomal segments between Phaseolus vulgaris and Vigna unguiculata, two species that diverged ~ 8 mya, were highly similar. Among the RLK/RLP synteny clusters, seven experimentally validated resistance RLK/RLP genes were identified in syntenic blocks. The RLK resistant genes FLS2, BIR2, ERECTA, IOS1, and AtSERK1 from Arabidopsis and SLSERK1 from Solanum lycopersicum were present in different pairwise syntenic blocks among the legume species. Meanwhile, only the LYM1- RLP resistant gene from Arabidopsis shared a syntenic blocks with Glycine max. Conclusions The orthology analysis of the RLK and RLP suggests a dynamic evolution in the legume family, with between 66 to 85% of RLK and 83 to 88% of RLP belonging to orthologous clusters among the species evaluated. In fact, for the 10-species comparison, a lower number of singleton proteins were reported among RLP compared to RLK, suggesting that RLP positions are more physically conserved compared to RLK. The identification of RLK and RLP genes among the synteny blocks in legumes revealed multiple highly conserved syntenic blocks on multiple chromosomes. Additionally, the analysis suggests that P. vulgaris is an appropriate anchor species for comparative genomics among legumes.


2013 ◽  
Vol 17 (3) ◽  
pp. 304-326 ◽  
Author(s):  
Catherine Larsen ◽  
Barbara Stacy Rieckhoff

PLoS ONE ◽  
2011 ◽  
Vol 6 (5) ◽  
pp. e19585 ◽  
Author(s):  
Arpana Vibhuti ◽  
Kshitij Gupta ◽  
Hariharan Subramanian ◽  
Qiang Guo ◽  
Hydar Ali

2021 ◽  
pp. mbc.E21-01-0039
Author(s):  
Renin Hazan ◽  
Munemasa Mori ◽  
Paul S. Danielian ◽  
Vincent J. Guen ◽  
Seth M. Rubin ◽  
...  

Multiciliated cells play critical roles in the airway, reproductive organs and brain. Generation of multiple cilia requires both activation of a specialized transcriptional program and subsequent massive amplification of centrioles within the cytoplasm. The E2F4 transcription factor is required for both roles, and consequently for multiciliogenesis. Here, we establish that E2F4 associates with two distinct components of the centriole replication machinery, Deup1 and SAS6, targeting non-homologous domains in these proteins. We map Deup1 and SAS6 binding to E2F4’s N-terminus, and show that this domain is sufficient to mediate E2F4’s cytoplasmic role in multiciliogenesis. This sequence is highly conserved across the E2F family, but the ability to bind Deup1 and SAS6 is specific to E2F4 and E2F5, consistent with their shared roles in multiciliogenesis. By generating E2F4/E2F1 chimeras, we identify a six-residue motif that is critical for Deup1 and SAS6 binding. We propose that the ability of E2F4 and E2F5 to recruit Deup1 and/or SAS6, and enable centriole replication, contributes to their cytoplasmic roles in multiciliogenesis.


Author(s):  
Carolyn Colvin ◽  
Jay Arduser ◽  
Elizabeth Willmore

This chapter explores and challenge the perception that immigrant parents demonstrate a kind of caring and advocacy that differs from dominant majority parents. It situates the case of one Salvadoran parent in the larger context of research that documents the differing communication practices of immigrant parents and teachers who teach their children. Teachers may misinterpret communication practices and participation in school events as a lack of caring. Using the story of Margarita, a Salvadoran parent of three children, the chapter demonstrates the experiences of one immigrant parent interacting with rural teachers to show how Latina/o parents are involved and actively advocate for their children’s academic futures. It concludes with a call to educators to adopt new visions of working with immigrant parents in jointly constructed activities where both parents and teachers assume shared roles of learning to solve problems, and to learn to work across diverse experiences.


2005 ◽  
Vol 26 (7) ◽  
pp. 924-946 ◽  
Author(s):  
Roderic Beaujot ◽  
Jianye Liu

Models of time use need to consider especially the reproductive and productive activities of women and men. For husband-wife families, the breadwinner, one-earner, or complementary-roles model has advantages in terms of efficiency or specialization and stability; however, it is a high-risk model for women and children. The alternate model has been called two-earner, companionship, “new families,” or collaborative in the sense of spouses collaborating in the paid and unpaid work needed to provide for and care for the family. Adopting the common metric of time use to study paid and unpaid work, we find that the complementary-roles model remains the most common, and the “double burden” is the second most frequent; however, there is some evidence of change in the direction of shared-roles arrangements, especially for younger couples with children, when both are employed full-time.


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