Blood flow in the skin of type 1 diabetic patients before and after combined pancreas/kidney transplantation

2005 ◽  
Vol 21 (6) ◽  
pp. 525-532 ◽  
Author(s):  
Nicola Eberl ◽  
Wolfgang Piehlmeier ◽  
Stefan Dachauer ◽  
August König ◽  
Walter Land ◽  
...  
Keyword(s):  
Blood Flow ◽  
Kidney Transplantation ◽  
Diabetic Patients ◽  
Before And After ◽  
Pancreas Kidney Transplantation ◽  
Type 1 Diabetic Patients

Elevated MBL levels in type 1 diabetic patients are reversed after simultaneous pancreas–kidney transplantation

2014 ◽  
Vol 31 (4) ◽  
pp. 226
Author(s):  
Pieter van der Pol ◽  
Danielle J. van Gijlswijk-Jansen ◽  
Roel Bijkerk ◽  
Eelco J.P. de Koning ◽  
Johan W. de Fijter ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Diabetic Patients ◽  
Pancreas Kidney Transplantation ◽  
Simultaneous Pancreas Kidney ◽  
Type 1 Diabetic Patients ◽  
Simultaneous Pancreas Kidney Transplantation

Decreased distensibility of resistance vessels of the skin in type 1 (insulin-dependent) diabetic patients with microangiopathy

1987 ◽  
Vol 72 (1) ◽  
pp. 123-130 ◽  
Author(s):  
J. Kastrup ◽  
T. Nørgaard ◽  
H.-H. Parving ◽  
N. A. Lassen
Keyword(s):  
Blood Flow ◽  
Inverse Correlation ◽  
Diabetic Patients ◽  
Resistance Vessels ◽  
Head Up Tilt ◽  
Insulin Dependent ◽  
Insulin Dependent Diabetic ◽  
Type 1 Diabetic Patients ◽  
Term Type

1. The distensibility of the resistance vessels of the skin at the dorsum of the foot was determined in 11 long-term type 1 (insulin-dependent) diabetic patients with nephropathy and retinopathy, nine short-term type 1 diabetic patients without clinical microangiopathy and in nine healthy non-diabetic subjects. 2. Blood flow was measured by the local 133Xexenon washout technique in a vascular bed locally paralysed by the injection of histamine. Blood flow was measured before, during and after a 40 mmHg increase of the vascular transmural pressure, induced by head-up tilt. 3. The mean increase in blood flow during headup tilt was only 24% in diabetic subjects with and 48% in diabetic patients without clinical microangiopathy, compared with 79% in normal non-diabetic subjects (P < 0.0005 and P < 0.05, respectively). 4. An inverse correlation between microvascular distensibility and degree of hyalinosis of the terminal arterioles in biopsies from the skin was demonstrated (r = − 0.57, P < 0.001). 5. Our results suggest that terminal arteriolar hyalinosis reduces the microvascular distensibility and probably increases the minimal vascular resistance, thereby impeding hyperaemic responses.

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