Repeated cross‐fostering affects maternal behavior and olfactory preferences in rat pups

2020 ◽  
Vol 62 (3) ◽  
pp. 283-296 ◽  
Author(s):  
Andrea Dulor Finkler ◽  
Grace Violeta Espinoza Pardo ◽  
Aldo Bolten Lucion
Keyword(s):  
Maternal Behavior ◽  
Rat Pups ◽  
Olfactory Preferences ◽  
Cross Fostering

scholarly journals Cross-Fostering of Male Mice Subtly Affects Female Olfactory Preferences

PLoS ONE ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. e0146662 ◽  
Author(s):  
Ying-Juan Liu ◽  
Yao-Hua Zhang ◽  
Lai-Fu Li ◽  
Rui-Qing Du ◽  
Jin-Hua Zhang ◽  
...  
Keyword(s):  
Male Mice ◽  
Olfactory Preferences ◽  
Cross Fostering

Su2080 Limited Nesting Stress Alters Maternal Behavior and In Vivo Intestinal Permeability in a Sex-Dependent Manner in Wistar Rat Pups

2016 ◽  
Vol 150 (4) ◽  
pp. S629
Author(s):  
Nabila Moussaoui ◽  
Muriel H. Larauche ◽  
Mandy Biraud ◽  
Jenny Molet ◽  
Mulugeta Million ◽  
...  
Keyword(s):  
Intestinal Permeability ◽  
Maternal Behavior ◽  
Wistar Rat ◽  
Dependent Manner ◽  
Rat Pups

Olfactory Preferences of Inbred Mice (Mus Musculus) for Their Own Strain and for Siblings: Effects of Strain, Sex and Cross-Fostering

Behaviour ◽  
1981 ◽  
Vol 78 (3-4) ◽  
pp. 314-323 ◽  
Author(s):  
Linda Partridge ◽  
Bruno D'Udine
Keyword(s):  
Foster Parents ◽  
Inbred Mice ◽  
Inbred Strains ◽  
The Other ◽  
Significant Preference ◽  
Slight Degree ◽  
Opposite Sex ◽  
Males And Females ◽  
Olfactory Preferences ◽  
Cross Fostering

Abstract1. Mice of two inbred strains (C57 BL 6/J and SEC I ReJ) were tested for their preferences for the smells of bedding used by mice of the opposite sex of the same two strains. 2. C57 males and females showed no significant preference between the smell of C57 and SEC and this result was unaffected if the mice were reared by SEC foster-parents. 3. SEC males and females preferred the smell of SEC to the smell of C57 and this result was unaffected if the mice were reared by C57 foster-parents. 4. Males of both strains preferred the smell of non-siblings of their own strain to the smell of siblings. Rearing by foster-parents of the other strain reversed this preference; the males then preferred the smell of siblings. 5. C57 females preferred the smell of siblings to the smell of non-siblings of the same strain and this result was unaffected by rearing by SEC foster-parents. 6. Female SEC showed no significant sibling preferences and this result was unaffected by rearing by C57 foster-parents. 7. The results are consistent with the idea that mice prefer a slight degree of unfamiliarity in the smell of the opposite sex but they also suggest that what was judged as unfamilar differed between the two strains.

Effect of methamphetamine exposure and cross-fostering on sensorimotor development of male and female rat pups

2009 ◽  
Vol 51 (1) ◽  
pp. 73-83 ◽  
Author(s):  
Lenka Hrubá ◽  
Barbora Schutová ◽  
Romana Šlamberová ◽  
Marie Pometlová ◽  
Richard Rokyta
Keyword(s):  
Female Rat ◽  
Male And Female ◽  
Sensorimotor Development ◽  
Rat Pups ◽  
Cross Fostering

scholarly journals The Behavior and Postnatal Development in Infant and Juvenile Rats After Ultrasound-Induced Chronic Prenatal Stress

2021 ◽  
Vol 12 ◽  
Author(s):  
Olga Abramova ◽  
Valeria Ushakova ◽  
Yana Zorkina ◽  
Eugene Zubkov ◽  
Zinaida Storozheva ◽  
...  
Keyword(s):  
Psychological Stress ◽  
Maternal Behavior ◽  
Prenatal Stress ◽  
Social Play ◽  
Play Behavior ◽  
Variable Frequency ◽  
Neonatal Handling ◽  
Rat Pups ◽  
Social Play Behavior ◽  
Frequency Ultrasound

Fetal development is susceptible to environmental factors. One such factor is exposure to stress during pregnancy. The present study aimed to investigate the effects of chronic prenatal stress (PS) on the development and behavior of rat offspring during infancy and juvenile ages. Existing approaches to modeling prenatal stress on animals do not correlate with the main type of stress in pregnant women, namely psychological stress. We used a new stress paradigm in the experiment, namely, stress induced by exposure to variable frequency ultrasound (US), which acted on pregnant Wistar rats on gestational days 1–21. This type of stress in rodents can be comparable to psychological stress in humans. We assessed physical development, reflex maturation, motor ability development, anxious behavior, response to social novelty, and social play behavior in male and female offspring. Additionally, we investigated maternal behavior and the effect of neonatal handling (NH) on behavior. Prenatal stress did not affect postnatal developmental characteristics in rat pups, but prenatally stressed rats had higher body weight in early and adult age than controls. Prenatal exposure to a stressor increased anxiety in the open-field test (OF), changed social preferences in the social novelty test (SN), and impaired social play behavior in males. Neonatal handling reduced anxiety and restored social behavior, but evoked hyperactive behavior in rat pups. Maternal behavior did not change. Our study demonstrated for the first time that exposure to variable frequency ultrasound during pregnancy influences offspring development and impairs behavior, correlating with the effects of other types of stress during pregnancy in rodents. This supports the idea of using this exposure to model prenatal stress.

scholarly journals Developmental Timing of the Effects of Maternal Care on Gene Expression and Epigenetic Regulation of Hormone Receptor Levels in Female Rats

Endocrinology ◽  
2013 ◽  
Vol 154 (11) ◽  
pp. 4340-4351 ◽  
Author(s):  
Catherine Jensen Peña ◽  
Y. Dana Neugut ◽  
Frances A. Champagne
Keyword(s):  
Dna Methylation ◽  
Maternal Behavior ◽  
Maternal Care ◽  
Female Offspring ◽  
Oxytocin Receptor ◽  
Developmental Timing ◽  
Mrna Levels ◽  
Receptor Mrna ◽  
Histone 3 ◽  
Cross Fostering

Maternal care experienced during postnatal development has enduring effects on neuroendocrine function and behavior. Previous studies in rats have illustrated the effect of maternal licking/grooming (LG) on hormone receptors and maternal behavior of adult female offspring associated with altered DNA methylation. However, the developmental timing of these effects, which provide insight into the cellular and molecular pathways through which early experience alters later behavior, had not been explored. Here, we demonstrate the developmental emergence of these outcomes and use cross-fostering to identify sensitive periods for these effects. Estrogen receptor (ER)α and ERβ mRNA levels within the medial preoptic area (MPOA) of the hypothalamus were increased by postnatal day (PN)21 in female offspring of high LG dams; LG-associated increases in oxytocin receptor mRNA levels were observed beyond the weaning period. Quantification of ERα-immunoreactivity indicated a high degree of neuroanatomical specificity of LG effects within the MPOA that were observed by PN6. Reduced DNA methylation and histone 3 lysine 9 tri-methylation and increased histone 3 lysine 4 tri-methylation at the ERα gene promoter (Esr1) were detected at PN21 in high LG female offspring. Latency to engage in maternal behavior toward donor pups was significantly shorter among high LG females. Cross-fostering revealed that maternal sensitization and MPOA ERα levels are sensitive to maternal care experienced before but not after PN10. Differential windows of plasticity were identified for ERβ and oxytocin receptor mRNA levels. These studies contribute significantly to our understanding of the molecular, neurobiological, and behavioral pathways through which variation in maternal behavior is transmitted from one generation to the next.

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