False-positive diagnosis in fine-needle aspiration of an atypical Warthin's tumor: Histochemical differential stains for cytodiagnosis

1989 ◽  
Vol 5 (4) ◽  
pp. 412-415 ◽  
Author(s):  
Rodolfo Laucirica ◽  
James B. Farnum ◽  
Sophie K. Leopold ◽  
George B. Kalin ◽  
George A. Youngberg
Keyword(s):  
Fine Needle Aspiration ◽  
False Positive ◽  
Needle Aspiration ◽  
Warthin’S Tumor ◽  
Fine Needle ◽  
Positive Diagnosis ◽  
False Positive Diagnosis ◽  
Warthin's Tumor

Fine-Needle Aspiration in the Diagnosis of Head and Neck Growths: The Pitfalls of False-Positive Diagnosis

ORL ◽  
1993 ◽  
Vol 55 (1) ◽  
pp. 41-44 ◽  
Author(s):  
Jean-Philippe Guyot ◽  
Serge Auberson ◽  
Dragan Obradovic ◽  
Willy Lehmann
Keyword(s):  
Head And Neck ◽  
Fine Needle Aspiration ◽  
False Positive ◽  
Needle Aspiration ◽  
Fine Needle ◽  
Positive Diagnosis ◽  
False Positive Diagnosis

Acute Parotitis as a Complication of Fine-Needle Aspiration in Warthin's Tumor. A Unique Finding of a 3-Year Experience with Parotid Tumor Aspiration

2006 ◽  
Vol 134 (4) ◽  
pp. 646-649 ◽  
Author(s):  
Gideon Bahar ◽  
Mickey Dudkiewicz ◽  
Raphael Feinmesser ◽  
Ben-Zion Joshua ◽  
Diana Braslavsky ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Parotid Tumor ◽  
Warthin’S Tumor ◽  
Fine Needle ◽  
Warthin's Tumor

Pitfalls in Salivary Gland Fine-Needle Aspiration Cytology: Lessons From the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology

2005 ◽  
Vol 129 (1) ◽  
pp. 26-31 ◽  
Author(s):  
Jonathan H. Hughes ◽  
Emily E. Volk ◽  
David C. Wilbur
Keyword(s):  
Salivary Gland ◽  
Fine Needle Aspiration ◽  
False Positive ◽  
Interlaboratory Comparison ◽  
False Negative ◽  
Diagnostic Errors ◽  
Poor Performance ◽  
Needle Aspiration ◽  
Low Grade ◽  
Fine Needle

Abstract Context.—We use data from the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology to identify common diagnostic errors in salivary gland fine-needle aspiration (FNA). Objective.—To identify salivary gland FNA cases with poor performance characteristics in the Nongynecologic Cytology Program surveys, so that the most common diagnostic pitfalls can be avoided. Design.—A retrospective review of the College of American Pathologists Nongynecologic Cytology Program's cumulative data from 1999 to 2003 revealed the most common false-positive and false-negative interpretations on FNA for common salivary gland lesions. Slides that performed poorly were then reviewed to identify the cytologic characteristics that may have contributed to their poor performance. Results.—A total of 6249 participant responses with general interpretations of benign (n = 4642) or malignant (n= 1607) were reviewed. The sensitivity and specificity of the participant responses for correctly interpreting the cases as benign or malignant were 73% and 91%, respectively. Benign cases with the highest false-positive rates were monomorphic adenoma (53% false-positive), intraparotid lymph node (36%), oncocytoma (18%), and granulomatous sialadenitis (10%). Malignant cases with the highest false-negative rates were lymphoma (57%), acinic cell carcinoma (49%), low-grade mucoepidermoid carcinoma (43%), and adenoid cystic carcinoma (33%). Selected review of the most discordant individual cases revealed possible explanations for some of the interpretative errors. Conclusions.—These data confirm the difficulty associated with interpretation of salivary gland FNA specimens. Cytologists should be aware of the potential false-positive and false-negative interpretations that can occur in FNAs from this organ site in order to minimize the possibility of diagnostic errors.

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