Vitamin D deficiency in dialysis patients and its effect on various disease markers

2009 ◽  
Vol 38 (11) ◽  
pp. 461-464 ◽  
Author(s):  
Adel B. Korkor ◽  
Christine M. Bretzmann ◽  
Daniel C. Eastwood
2016 ◽  
Vol 5 ◽  
pp. 1015-1022 ◽  
Author(s):  
Cristina Căpuşă ◽  
Gabriel Stefan ◽  
Simona Stancu ◽  
Andrea Ilyes ◽  
Nicoleta Dorobanţu ◽  
...  

2011 ◽  
Vol 76 (08) ◽  
pp. 110-116 ◽  
Author(s):  
H. Taskapan ◽  
O. Baysal ◽  
D. Karahan ◽  
B. Durmus ◽  
Z. Altay ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Stig Molsted ◽  
Pia Eiken ◽  
Jesper L. Andersen ◽  
Inge Eidemak ◽  
Adrian P. Harrison

Background. The aim of this study was to investigate IL-6 and 25-hydroxyvitamin D (25-OH D) associations with muscle size and muscle function in dialysis patients.Methods. Patients were included in a 16-week control period followed by 16 weeks of high-intensity resistance training thrice weekly. IL-6 and 25-OH D were analysed after an over-night fast. Muscle fibre size was analysed in biopsies fromm. vastus lateralis. Muscle power was tested using a Leg Extensor Power Rig.Results. Patients (n=36) with IL-6 ≥ 6.49 pg/ml (median) were older and had decreased muscle power and a reduced protein intake (P<0.05) compared with patients with IL-6 < 6.49 pg/ml. IL-6 was not associated with muscle fibre size. Vitamin D deficiency (25-OH D < 50 nmol/l) was present in 51% of the patients and not associated with muscle power. IL-6 remained unchanged during the training period, whilst muscle power increased by 20–23% (P<0.001).Conclusion. Elevated IL-6 values were associated with decreased muscle power but not with decreased muscle fibre size. Half of the patients were suffering from vitamin D deficiency, which was not associated with muscle power. IL-6 was unchanged by high-intensity resistance training in dialysis patients in this study.


2012 ◽  
Vol 45 (3) ◽  
pp. 879-884 ◽  
Author(s):  
Ozkan Ulutas ◽  
Hulya Taskapan ◽  
Mehmet Cagatay Taskapan ◽  
Ismail Temel

Author(s):  
Andressa Keiko Matsumoto ◽  
Michael Maes ◽  
Ana Paula Michelin ◽  
Abel Esteves Soares ◽  
Laura de Oliveira Semeão ◽  
...  

Abstract Introduction: The progressive decline in 25-hydroxyvitamin D [25(OH)D] in chronic kidney disease (CKD) limits the kidney ability of synthesizing the vitamin. Vitamin D deficiency as defined by KDIGO (25(OH)D <20 ng/mL) is prevalent in CKD patients and associated to oxidative stress (OS). We studied a possible association between vitamin D deficiency and OS in pre-dialysis patients. Methods: A cross-sectional study with 206 CKD patients was carried out. Laboratory tests for 25(OH)D, 1,25(OH)2D, inflammatory markers, and OS were added to routine tests including creatinine, albumin, calcium, phosphorus, alkaline phosphatase, iPTH, glucose, hemoglobin, uric acid, total cholesterol, LDL, HDL, and triglycerides. Results: Vitamin D deficiency was present in 55 CKD patients and normal vitamin D levels were seen in 149 patients. There was a significant association between vitamin D and estimated glomerular filtration rate (eGRF). Homocysteine levels were best predicted by eGRF, sex, and age; high sensitivity C-reactive protein (hsCRP) by staging and BMI; nitric oxide metabolites (NOx) were increased in late disease; leptin was influenced by BMI and higher in women than man; and adiponectin levels were higher in women. Conclusions: OS biomarkers were not correlated with vitamin D deficiency but increased NOx were seen in stages 4-5 CKD patients. Even though a relatively large number of CKD patients was included and a broad number of OS and inflammatory biomarkers were used in this studied we failed to find an association between vitamin D levels and eGRF. More studies are needed to evaluate the influence of vitamin D status in OS in pre-dialysis CKD patients.


2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii687-iii687
Author(s):  
Rosario Luxardo ◽  
Edwin Ramirez ◽  
Tomas Fescina ◽  
Mariela Bedini Roca ◽  
Soledad Crucelegui ◽  
...  

2010 ◽  
Vol 20 (6) ◽  
pp. 359-367 ◽  
Author(s):  
Carolina Gracia-Iguacel ◽  
Paloma Gallar ◽  
Abdul R. Qureshi ◽  
Olimpia Ortega ◽  
Carmen Mon ◽  
...  

2014 ◽  
Vol 25 (5) ◽  
pp. 981
Author(s):  
JamalS Alwakeel ◽  
Saira Usama ◽  
AhmadH Mitwalli ◽  
Abdulkareem Alsuwaida ◽  
Mohammed Alghonaim

2015 ◽  
Vol 2 ◽  
pp. 75-81
Author(s):  
Hari Krishan Aggarwal ◽  
Deepak Jain ◽  
Anshul Mittal ◽  
Sunil Pawar ◽  
Rajpal Ver

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