scholarly journals The prevalence of vitamin D deficiency in pre-dialysis patients with chronic kidney disease

2015 ◽  
Vol 2 ◽  
pp. 75-81
Author(s):  
Hari Krishan Aggarwal ◽  
Deepak Jain ◽  
Anshul Mittal ◽  
Sunil Pawar ◽  
Rajpal Ver
Keyword(s):  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Kidney Disease ◽  
Vitamin D Deficiency ◽  
Dialysis Patients

scholarly journals Vitamin D deficiency is not associated with increased oxidative stress in chronic kidney disease pre-dialysis patients

2020 ◽  
Author(s):  
Andressa Keiko Matsumoto ◽  
Michael Maes ◽  
Ana Paula Michelin ◽  
Abel Esteves Soares ◽  
Laura de Oliveira Semeão ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Kidney Disease ◽  
Vitamin D Deficiency ◽  
High Sensitivity ◽  
Cross Sectional Study ◽  
Dialysis Patients ◽  
Cross Sectional ◽  
Vitamin D Levels

Abstract Introduction: The progressive decline in 25-hydroxyvitamin D [25(OH)D] in chronic kidney disease (CKD) limits the kidney ability of synthesizing the vitamin. Vitamin D deficiency as defined by KDIGO (25(OH)D <20 ng/mL) is prevalent in CKD patients and associated to oxidative stress (OS). We studied a possible association between vitamin D deficiency and OS in pre-dialysis patients. Methods: A cross-sectional study with 206 CKD patients was carried out. Laboratory tests for 25(OH)D, 1,25(OH)2D, inflammatory markers, and OS were added to routine tests including creatinine, albumin, calcium, phosphorus, alkaline phosphatase, iPTH, glucose, hemoglobin, uric acid, total cholesterol, LDL, HDL, and triglycerides. Results: Vitamin D deficiency was present in 55 CKD patients and normal vitamin D levels were seen in 149 patients. There was a significant association between vitamin D and estimated glomerular filtration rate (eGRF). Homocysteine levels were best predicted by eGRF, sex, and age; high sensitivity C-reactive protein (hsCRP) by staging and BMI; nitric oxide metabolites (NOx) were increased in late disease; leptin was influenced by BMI and higher in women than man; and adiponectin levels were higher in women. Conclusions: OS biomarkers were not correlated with vitamin D deficiency but increased NOx were seen in stages 4-5 CKD patients. Even though a relatively large number of CKD patients was included and a broad number of OS and inflammatory biomarkers were used in this studied we failed to find an association between vitamin D levels and eGRF. More studies are needed to evaluate the influence of vitamin D status in OS in pre-dialysis CKD patients.

scholarly journals Clinicians should be more prone to examine children with chronic kidney disease in terms of vitamin D deficiency

2013 ◽  
Vol 33 (2) ◽  
pp. 201-201
Author(s):  
Sevket Balta ◽  
Mustafa Cakar ◽  
Seref Demirbas ◽  
Sait Demirkol
Keyword(s):  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Kidney Disease ◽  
Vitamin D Deficiency

Vitamin D deficiency, insulin resistance, and ventricular hypertrophy in the early stages of chronic kidney disease

Renal Failure ◽  
2013 ◽  
Vol 36 (1) ◽  
pp. 58-64 ◽  
Author(s):  
Silvia Lai ◽  
Bettina Coppola ◽  
Mira Dimko ◽  
Alessandro Galani ◽  
Georgie Innico ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Kidney Disease ◽  
Vitamin D Deficiency ◽  
Ventricular Hypertrophy ◽  
Early Stages

scholarly journals Vitamin D deficiency is common in children and adolescents with chronic kidney disease

2012 ◽  
Vol 81 (7) ◽  
pp. 690-697 ◽  
Author(s):  
Heidi J. Kalkwarf ◽  
Michelle R. Denburg ◽  
C. Frederic Strife ◽  
Babette S. Zemel ◽  
Debbie L. Foerster ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Kidney Disease ◽  
Children And Adolescents ◽  
Vitamin D Deficiency
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