Disease-specific biomarker discovery by aptamers

2009 ◽  
Vol 75A (9) ◽  
pp. 727-733 ◽  
Author(s):  
Henning Ulrich ◽  
Carsten Wrenger
Keyword(s):  
Biomarker Discovery ◽  
Disease Specific

scholarly journals Autoimmune Encephalopathies and Epilepsies in Children and Teenagers

2012 ◽  
Vol 39 (2) ◽  
pp. 134-144 ◽  
Author(s):  
Lily C. Wong-Kisiel ◽  
Andrew McKeon ◽  
Elaine C. Wirrell
Keyword(s):  
Central Nervous System ◽  
Cerebral Spinal Fluid ◽  
Biomarker Discovery ◽  
Epileptic Encephalopathy ◽  
Cytotoxic T Cell ◽  
Central Nervous System Dysfunction ◽  
Clinical Presentations ◽  
Autoimmune Encephalopathy ◽  
Disease Specific ◽  
Autoimmune Etiology

Recognition of autoimmune encephalopathies and epilepsies in children and teenagers with acute or subacute onset of central nervous system dysfunction, through detection of the pertinent antibody on serum or cerebral spinal fluid, or through a response to immunotherapy may lead to an early diagnosis, and thus expedited implementation of immunotherapy and improved neurological outcome. The epidemiology of pediatric autoimmune encephalopathy and epilepsy is not well established, but advances in disease-specific biomarker discovery have lead to identification of disorders with either a cytotoxic T cell mediated pathogenesis or (more recently) possible autoantibody mediated disorders. This review summarizes the clinical presentations and recommended evaluations and treatment of pediatric epileptic encephalopathy suspected to be of autoimmune etiology.

HLA-DQ2 and/or-DQ9 is associated with coeliac disease specific autoantibodies to tissue transglutaminase in families with thyrold autoimmunity

2001 ◽  
Vol 120 (5) ◽  
pp. A393-A393
Author(s):  
D SCHUPPAN ◽  
W DIETERICH ◽  
S HOFMANN ◽  
M HUEFNER ◽  
K USADEL ◽  
...  
Keyword(s):  
Coeliac Disease ◽  
Tissue Transglutaminase ◽  
Disease Specific ◽  
Hla Dq2

1140: Prognostic Nomogram for Disease-Specific Survival of Patients with Untreated Androgen Independent Prostate Cancer

2005 ◽  
Vol 173 (4S) ◽  
pp. 310-310
Author(s):  
Robert S. Svatek ◽  
Pierre I. Karakiewicz ◽  
Michael J. Shulman ◽  
Jose Karam ◽  
Paul Perrotte ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Disease Specific Survival ◽  
Disease Specific ◽  
Androgen Independent

Disease-Specific Stressors Among Youths With HIV/AIDS: Toward Tailored Health Management

2006 ◽  
Author(s):  
Lisa A. Orban ◽  
Renee Stein ◽  
Linda J. Koenig ◽  
Erika L. Rexhouse ◽  
Ricardo D. Lagrange ◽  
...  
Keyword(s):  
Health Management ◽  
Disease Specific ◽  
Hiv Aids
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