scholarly journals Enhanced red and near infrared detection in flow cytometry using avalanche photodiodes

2008 ◽  
Vol 73A (8) ◽  
pp. 767-776 ◽  
Author(s):  
William G. Lawrence ◽  
Gyula Varadi ◽  
Gerald Entine ◽  
Edward Podniesinski ◽  
Paul K. Wallace
Keyword(s):  
Flow Cytometry ◽  
Near Infrared ◽  
Avalanche Photodiodes ◽  
Infrared Detection

Air-stable few-layer black phosphorus phototransistor for near-infrared detection

2017 ◽  
Vol 28 (8) ◽  
pp. 085201 ◽  
Author(s):  
Junhong Na ◽  
Kichul Park ◽  
Jin Tae Kim ◽  
Won Kook Choi ◽  
Yong-Won Song
Keyword(s):  
Near Infrared ◽  
Black Phosphorus ◽  
Infrared Detection

A 16-channel avalanche photodiode detector array for visible and near-infrared flow cytometry

2006 ◽  
Author(s):  
William G. Lawrence ◽  
Christopher Stapels ◽  
Richard Farrell ◽  
Joseph D. Tario, Jr. ◽  
Edward Podniesinski ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Near Infrared ◽  
Avalanche Photodiode ◽  
Detector Array

scholarly journals Temperature effects on characteristics and performance of near-infrared wide bandwidth for different avalanche photodiodes structures

2019 ◽  
Vol 14 ◽  
pp. 102399 ◽  
Author(s):  
I.S. Amiri ◽  
Fatma Mohammed Aref Mahmoud Houssien ◽  
Ahmed Nabih Zaki Rashed ◽  
Abd El-Naser A. Mohammed
Keyword(s):  
Temperature Effects ◽  
Near Infrared ◽  
Avalanche Photodiodes ◽  
Wide Bandwidth ◽  
And Performance

scholarly journals Imaging Cardiovascular and Lung Macrophages With the Positron Emission Tomography Sensor 64 Cu-Macrin in Mice, Rabbits, and Pigs

2020 ◽  
Vol 13 (10) ◽  
Author(s):  
Matthias Nahrendorf ◽  
Friedrich Felix Hoyer ◽  
Anu E. Meerwaldt ◽  
Mandy M.T. van Leent ◽  
Max L. Senders ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Flow Cytometry ◽  
Confocal Microscopy ◽  
Pet Imaging ◽  
Near Infrared ◽  
Emission Tomography ◽  
Imaging Biomarker ◽  
Positron Emission ◽  
Pulmonary Macrophages

Background: Macrophages, innate immune cells that reside in all organs, defend the host against infection and injury. In the heart and vasculature, inflammatory macrophages also enhance tissue damage and propel cardiovascular diseases. Methods: We here use in vivo positron emission tomography (PET) imaging, flow cytometry, and confocal microscopy to evaluate quantitative noninvasive assessment of cardiac, arterial, and pulmonary macrophages using the nanotracer 64 Cu-Macrin—a 20-nm spherical dextran nanoparticle assembled from nontoxic polyglucose. Results: PET imaging using 64 Cu-Macrin faithfully reported accumulation of macrophages in the heart and lung of mice with myocardial infarction, sepsis, or pneumonia. Flow cytometry and confocal microscopy detected the near-infrared fluorescent version of the nanoparticle ( VT680 Macrin) primarily in tissue macrophages. In 5-day-old mice, 64 Cu-Macrin PET imaging quantified physiologically more numerous cardiac macrophages. Upon intravenous administration of 64 Cu-Macrin in rabbits and pigs, we detected heightened macrophage numbers in the infarcted myocardium, inflamed lung regions, and atherosclerotic plaques using a clinical PET/magnetic resonance imaging scanner. Toxicity studies in rats and human dosimetry estimates suggest that 64 Cu-Macrin is safe for use in humans. Conclusions: Taken together, these results indicate 64 Cu-Macrin could serve as a facile PET nanotracer to survey spatiotemporal macrophage dynamics during various physiological and pathological conditions. 64 Cu-Macrin PET imaging could stage inflammatory cardiovascular disease activity, assist disease management, and serve as an imaging biomarker for emerging macrophage-targeted therapeutics.

scholarly journals Humanized Anti–Tumor-Associated Glycoprotein–72 for Submillimeter Near-Infrared Detection of Colon Cancer in Metastatic Mouse Models

2020 ◽  
Vol 252 ◽  
pp. 16-21 ◽  
Author(s):  
Hannah M. Hollandsworth ◽  
Siamak Amirfakhri ◽  
Filemoni Filemoni ◽  
Robert M. Hoffman ◽  
Justin Molnar ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Mouse Models ◽  
Near Infrared ◽  
Infrared Detection
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