scholarly journals A feasibility study: association between gut microbiota enterotype and antibody response to seasonal trivalent influenza vaccine in adults

2018 ◽  
Vol 7 (3) ◽  
pp. e1013
Author(s):  
Nick Shortt ◽  
Hazel Poyntz ◽  
Wayne Young ◽  
Angela Jones ◽  
Aurélie Gestin ◽  
...  
2015 ◽  
Vol 11 (2) ◽  
pp. 386-390 ◽  
Author(s):  
Satoshi Hiroi ◽  
Saeko Morikawa ◽  
Keiko Nakata ◽  
Akiko Maeda ◽  
Tsuneji Kanno ◽  
...  

1986 ◽  
Vol 96 (3) ◽  
pp. 513-522 ◽  
Author(s):  
Walter E. P. Beyer ◽  
Jos T. M. Van Der Logt ◽  
Ruud van Beek ◽  
Nic Masurel

SUMMARYFifty volunteers, treated with an inactivated trivalent influenza vaccine containing A/Bangkok/1/79 (H3N2), A/Brazil/11/78 (H1N1) and B/Singapore/222/79 virus, were subdivided according to the estimated first exposure to influenza in their lifetime (priming) and the presence of antibodies against the vaccine components in the pre-vaccination sera. The isotypic antibody response (IgG, IgA, IgM) was determined by means of an antibody capture haemadsorption immunosorbent technique. For all three vaccine components, previously seropositive subjects produced antibodies of the IgG- and IgA-class more frequently than previously seronegative persons. Subjects primed to one of the influenza A subtypes showed more IgG and IgA responses in comparison with those unprimed (prime-effect). In contrast, IgM antibodies occurred in only 19 and 11% of primed, but in 59 and 54% of unprimed subjects, for A (H3N2) and A (HlNl), respectively. The incidence of IgM titre rises was not influenced by the prevaccination state. However, the mean magnitude of anti-A(H1N1)-IgM titre rises was greater in those previously seronegative. The concepts of primary and reinfection and of ‘original antigenic sin’ are discussed, and it is suggested that age and, if possible, serological state prior to antigen-exposure should be taken into account when studying isotypic antibody responses after influenza infection or vaccination.


Vaccine ◽  
2012 ◽  
Vol 30 (2) ◽  
pp. 436-441 ◽  
Author(s):  
Ema Sacadura-Leite ◽  
Antonio Sousa-Uva ◽  
Helena Rebelo-de-Andrade

Vaccine ◽  
2020 ◽  
Vol 38 (33) ◽  
pp. 5171-5177
Author(s):  
Krissy K. Moehling ◽  
Richard K. Zimmerman ◽  
Mary Patricia Nowalk ◽  
Chyongchiou Jeng Lin ◽  
Judith M. Martin ◽  
...  

2010 ◽  
Vol 54 (5) ◽  
pp. 716-720 ◽  
Author(s):  
Elham Shahgholi ◽  
Mohammad Ali Ehsani ◽  
Payman Salamati ◽  
Alipasha Maysamie ◽  
Kambiz Sotoudeh ◽  
...  

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