Effect of a standard breakfast on digoxin absorption in normal subjects

1978 ◽  
Vol 23 (3) ◽  
pp. 315-319 ◽  
Author(s):  
B. F. Johnson ◽  
J. O'Grady ◽  
G. A. Sabey ◽  
Carole Bye
Keyword(s):  
Normal Subjects ◽  
Digoxin Absorption ◽  
Standard Breakfast

Measurement of acetate in human blood by gas chromatography: effects of sample preparation, feeding, and various diseases.

1979 ◽  
Vol 25 (10) ◽  
pp. 1787-1790 ◽  
Author(s):  
C D Tollinger ◽  
H J Vreman ◽  
M W Weiner
Keyword(s):  
Gas Chromatography ◽  
Whole Blood ◽  
Normal Subjects ◽  
Acetate Concentration ◽  
Disease States ◽  
Severe Liver Disease ◽  
Arterial Plasma ◽  
Standard Breakfast ◽  
Hydrolysis Of ◽  
Venous Plasma

Abstract We measured acetate concentrations in whole blood, serum, and plasma by a modification of a previously described method involving vacuum distillation and gas chromatography. The mean acetate concentration of fresh venous plasma from 27 normal subjects was 51 +/- 5 mumol/L (95% confidence limits ranged from 0 to 103 mumol/L). The acetate concentrations of serum and plasma incubated for 2 h at either 4 degrees C or 27 degrees C were the same. The acetate concentration of whole blood incubated at 27 degrees C was significantly greater than that of blood incubated at 4 degrees C. This change may have resulted from the production of acetate by erythrocytes or from the hydrolysis of acetate esters. Storage of plasma at -20 degrees C for 24 h significantly increased acetate concentrations from 26 +/- 6 mumol/L to 63 +/- 4 mumol/L. After the subjects consumed a standard breakfast, venous plasma acetate concentrations increased from 58 to 97 mumol/L at 30 min. Acetate concentrations in arterial plasma exceeded those in venous plasma. Plasma acetate concentrations were not significantly altered in patients with malignancy or diabetes mellitus, but severe liver disease and severe acidosis were both associated with increased acetate concentrations. These preliminary observations suggest that plasma acetate concentrations may be altered in several disease states.

Auditory Selective Attention in Cerebral-Palsied Individuals

1985 ◽  
Vol 16 (4) ◽  
pp. 260-266 ◽  
Author(s):  
Lee Ann Laraway
Keyword(s):  
Selective Attention ◽  
White Noise ◽  
Normal Subjects ◽  
Auditory Selective Attention ◽  
Normal Individuals ◽  
Significant Difference

The purpose of this study was to determine whether there is a statistically significant difference between the auditory selective attention abilities of normal and cerebral-palsied individuals. Twenty-three cerebral-palsied and 23 normal subjects between the ages of 5 and 21 were asked to repeat a series of 30 items consisting of from 2 to 4 digits in the presence of intermittent white noise. Results of the study indicate that cerebral-palsied individuals perform significantly poorer than normal individuals when the stimulus is accompanied by noise. Noise was not a significant factor in the performance of the normal subjects regardless of age.

The Effect of Stapedectomy on the Loudness of One’s Own Voice

1965 ◽  
Vol 8 (3) ◽  
pp. 223-234 ◽  
Author(s):  
William Melnick
Keyword(s):  
Middle Ear ◽  
Normal Subjects ◽  
Sound Energy ◽  
Loudness Function ◽  
Before And After ◽  
Increased Sensitivity

Five subjects with normal middle ear mechanisms, and otosclerotic patients, before and after stapedectomy, matched the loudness of their voices to the loudness of a 125-cps-sawtooth noise. The results showed loudness matching functions with gradual slopes, less than 1.00, for the normal subjects and the patients prior to stapedectomy. Post-surgically, the loudness function for the patients increased in steepness to considerably more than 1.00. These results are explained, most logically, in terms of increased sensitivity of the altered middle ear to sound energy generated by the listener’s own voice.

Delayed Auditory Feedback with Different Delay Times at Each Ear

1964 ◽  
Vol 7 (4) ◽  
pp. 369-371
Author(s):  
Samuel Fillenbaum
Keyword(s):  
Delay Interval ◽  
Auditory Feedback ◽  
Normal Subjects ◽  
Delayed Auditory Feedback ◽  
Delay Times

Binaurally asynchronous delayed auditory feedback (DAF) was compared with synchronous DAF in 80 normal subjects. Asynchronous DAF (0.10 sec difference) did not yield results different from those obtained under synchronous DAF with a 0.20 sec delay interval, an interval characteristically resulting in maximum disruptions in speech.

Object Transformations in the Play of Language-Impaired Children

1988 ◽  
Vol 53 (4) ◽  
pp. 459-466 ◽  
Author(s):  
Brenda Y. Terrell ◽  
Richard G. Schwartz
Keyword(s):  
Normal Subjects ◽  
Play Behavior ◽  
Chronological Age ◽  
Standard Group ◽  
Language Impaired ◽  
Normal Language ◽  
Mean Length Of Utterance ◽  
Impaired Children

The play behavior of 10 language-impaired children was observed. Their performances in play were compared to those of 10 normal-language children matched for chronological age as well as to those of 10 normal-language children matched for mean length of utterance. The children were observed as they played spontaneously with a standard group of toys and as they played with objects that required object transformations for successful play. The chronological age-matched normal subjects showed a trend toward performance of more object transformations in play than either the language-impaired or younger normal-language children. Additionally, although object transformations were observed in both segments, all children performed more object transformations with objects than with toys.

Mechanical characteristics of the EGJ after fundoplication compared to normal subjects and GERD patients

2001 ◽  
Vol 120 (5) ◽  
pp. A112-A112 ◽  
Author(s):  
J CURRY ◽  
G SHI ◽  
J PANDOLFINO ◽  
R JOEHL ◽  
J BRASSEUR ◽  
...  
Keyword(s):  
Mechanical Characteristics ◽  
Normal Subjects
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