scholarly journals Solution Structure of Mannobioses Unravelled by Means of Raman Optical Activity

ChemPhysChem ◽  
2019 ◽  
Vol 20 (5) ◽  
pp. 695-705 ◽  
Author(s):  
Robert Pendrill ◽  
Shaun T. Mutter ◽  
Carl Mensch ◽  
Laurence D. Barron ◽  
Ewan W. Blanch ◽  
...  
Keyword(s):  
Optical Activity ◽  
Solution Structure ◽  
Raman Optical Activity

scholarly journals The effect of protein backbone hydration on the amide vibrations in Raman and Raman optical activity spectra

2019 ◽  
Vol 21 (4) ◽  
pp. 1988-2005 ◽  
Author(s):  
Carl Mensch ◽  
Patrick Bultinck ◽  
Christian Johannessen
Keyword(s):  
Optical Activity ◽  
Solution Structure ◽  
Protein Backbone ◽  
Raman Optical Activity

Raman and specifically Raman optical activity (ROA) spectroscopy are very sensitive to the solution structure and conformation of biomolecules.

Solution structure of native proteins with irregular folds from Raman optical activity

Biopolymers ◽  
2000 ◽  
Vol 58 (2) ◽  
pp. 138-151 ◽  
Author(s):  
Edward Smyth ◽  
Christopher D. Syme ◽  
Ewan W. Blanch ◽  
Lutz Hecht ◽  
Milan Va?�k ◽  
...  
Keyword(s):  
Optical Activity ◽  
Solution Structure ◽  
Native Proteins ◽  
Raman Optical Activity

Recent Developments in Raman Optical Activity of Biopolymers

1996 ◽  
Vol 50 (5) ◽  
pp. 619-629 ◽  
Author(s):  
L. D. Barron ◽  
L. Hecht ◽  
A. F. Bell ◽  
G. Wilson
Keyword(s):  
Secondary Structure ◽  
Nucleic Acids ◽  
Optical Activity ◽  
Solution Structure ◽  
Tertiary Structure ◽  
Molten Globule ◽  
Raman Optical Activity ◽  
Recent Developments ◽  
Different Temperatures ◽  
Carbohydrate Components

Recent advances in Raman optical activity (ROA) instrumentation are outlined which have enhanced significantly the quality of vibrational ROA spectra of biopolymers in aqueous solution. Peptides, proteins, carbohydrates, glycoproteins, and nucleic acids now provide excellent ROA spectra which contain detailed information about solution structure. ROA spectra can be measured just as easily in D2O as in H2O solution, and, as illustrated for bovine serum albumin and concanavalin A, a comparison of the two can be highly informative. In addition to signatures of extended secondary structure, protein ROA spectra also contain signatures related to loops and turns which are valuable for studying tertiary structure and dynamics, exemplified here by a comparison of the ROA spectra of reduced lysozyme and unordered poly-L-lysine, by the ROA spectra of acid molten globule α-lactalbumin at different temperatures, which reveal a native-like tertiary fold, and by changes in the ROA spectrum of native lysozyme on binding to a saccharide inhibitor. Carbohydrate ROA spectra contain signatures of all the central features of their stereochemistry and, as shown by a comparison of laminaribiose with laminarin, can also probe extended secondary structure in polysaccharides. Results on a glycoprotein, orosomucoid, suggest that ROA can provide information about both the protein and the carbohydrate components. Preliminary results on nucleic acids are outlined with the ROA spectra of Poly(rA)·Poly(rU) and Poly(rI)·Poly(rC) shown as examples.

Structural characterization of proteins and viruses using Raman optical activity

2004 ◽  
Vol 35 (1-2) ◽  
pp. 87-92 ◽  
Author(s):  
Ewan W Blanch ◽  
Iain H McColl ◽  
Lutz Hecht ◽  
Kurt Nielsen ◽  
Laurence D Barron
Keyword(s):  
Optical Activity ◽  
Structural Characterization ◽  
Raman Optical Activity

scholarly journals Recognition of the true and false resonance Raman optical activity

2021 ◽  
Author(s):  
Malgorzata Baranska ◽  
Ewa Machalska ◽  
Grzegorz Zajac ◽  
Aleksandra J. Wierzba ◽  
Josef Kapitán ◽  
...  
Keyword(s):  
Optical Activity ◽  
Resonance Raman ◽  
Raman Optical Activity

scholarly journals Recognition of the true and false resonance Raman optical activity

2021 ◽  
Author(s):  
Malgorzata Baranska ◽  
Ewa Machalska ◽  
Grzegorz Zajac ◽  
Aleksandra J. Wierzba ◽  
Josef Kapitán ◽  
...  
Keyword(s):  
Optical Activity ◽  
Resonance Raman ◽  
Raman Optical Activity
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