scholarly journals Pluronic micelles encapsulated curcumin manifests apoptotic cell death and inhibits pro-inflammatory cytokines in human breast adenocarcinoma cells

2018 ◽  
Vol 2 (1) ◽  
pp. e1133 ◽  
Author(s):  
Foram U. Vaidya ◽  
Rakesh Sharma ◽  
Sofiya Shaikh ◽  
Debes Ray ◽  
Vinod K. Aswal ◽  
...  
Keyword(s):  
Cell Death ◽  
Inflammatory Cytokines ◽  
Apoptotic Cell ◽  
Apoptotic Cell Death ◽  
Breast Adenocarcinoma ◽  
Human Breast ◽  
Human Breast Adenocarcinoma ◽  
Adenocarcinoma Cells ◽  
Pro Inflammatory Cytokines

Sulindac induces apoptotic cell death in susceptible human breast cancer cells through, at least in part, inhibition of IKKβ

APOPTOSIS ◽  
2009 ◽  
Vol 14 (7) ◽  
pp. 913-922 ◽  
Author(s):  
A-Mi Seo ◽  
Seung-Woo Hong ◽  
Jae-Sik Shin ◽  
In-Chul Park ◽  
Nam-Joo Hong ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Death ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Apoptotic Cell ◽  
Apoptotic Cell Death ◽  
Human Breast Cancer Cells ◽  
Human Breast

W1954 Sulforaphane, An Antioxidant Derived from Broccoli, Induces Apoptotic Cell Death in Barrett's Esophageal Adenocarcinoma Cells

2008 ◽  
Vol 134 (4) ◽  
pp. A-741
Author(s):  
Masood A. Shammas ◽  
Christopher S. Bryant ◽  
Sanjeev Kumar ◽  
Madhu Prasad ◽  
Christopher P. Steffes ◽  
...  
Keyword(s):  
Cell Death ◽  
Esophageal Adenocarcinoma ◽  
Apoptotic Cell ◽  
Apoptotic Cell Death ◽  
Adenocarcinoma Cells ◽  
Barrett’S Esophageal Adenocarcinoma

scholarly journals Change in the Expression of BAK، FAS، BAX، TNF-A، BCL-2 and Survivin Apoptosis Genes of the Human Breast Adenocarcinoma Cells (MCF-7) by Staphylococcal Enterotoxin B

2019 ◽  
Author(s):  
Sara Afzali ◽  
Abbas Doosti ◽  
Mansour Heidari ◽  
Nahid Babaei ◽  
Parvaneh Keshavarz
Keyword(s):  
Staphylococcal Enterotoxin ◽  
Breast Adenocarcinoma ◽  
Control Group ◽  
Staphylococcal Enterotoxin B ◽  
Type B ◽  
Human Breast ◽  
Human Breast Adenocarcinoma ◽  
Adenocarcinoma Cells ◽  
Enterotoxin B ◽  
Mcf 7

Introduction: Breast cancer is one of the most prevalent malignancies among women. Patients whose suffering from this condition, as a result of the use of conventional therapies often have a poor response to treatment and the relapse among them is frequent. In this study, the effects of staphylococcal enterotoxin type B on BAK، FAS، BAX، TNF-a، BCL-2 و Survivin genes expression in human breast adenocarcinoma cells (MCF-7) was examined. Staphylococcal enterotoxin B is a powerful member of the Staphylococcus aureus toxins family, which is known as an anticancer agent with potential for killing cancer cells. Methods: The experimental study was carried out at the Biotechnology Research Center of Islamic Azad University, Shahrekord Branch. By using Lipofectamine 2000 reagent, MCF-7  cells transfected with the pcDNA3.1(+)-seb (recombinant) and  pcDNA3.1(+) (non-recombinant)  plasmids and were selected by culturing in a selective medium of RPMI- 1640 containing 600 μg / mL antibiotic G418. Then, the expression of BAK, FAS, BAX, TNF-a, BCL-2, and Survivin genes in transfected cells were analyzed by real time PCR. Student's t-test, SPSS Inc., Chicago, IL; Version 16 and also Excel program for statistical analysis were used. Results: The results of this study indicated that staphylococcal enterotoxin type B (SEB) remarkably changes the expression of apoptotic related genes in MCF-7 cell line. It was observed a significant increase in the expression of BAK, FAS, BAX, and TNF-a genes, the expression of BCL-2 and Survivin genes significantly decreased compared to the control group (P=0/032). Conclusion: Staphylococcal enterotoxin type B has an inhibitory effect on the growth, proliferation and invasion of breast adenocarcinoma cells through altering the expression of the genes involved in the apoptosis process. Therefore, it seems that there is a good research field for the use of this toxin in the control and treatment of human breast adenocarcinoma.

Ultrastructural Assessment of 2-(acridin-9-ylmethylene)-N-phenylhydrazinecarbothioamide activity on human breast adenocarcinoma cells

Micron ◽  
2016 ◽  
Vol 90 ◽  
pp. 114-122 ◽  
Author(s):  
Sinara Mônica Vitalino de Almeida ◽  
Lúcia Patrícia Bezerra Gomes da Silva ◽  
Luiza Rayanna Amorim de Lima ◽  
Giovanna Barbarini Longato ◽  
Rafael José Ribeiro Padilha ◽  
...  
Keyword(s):  
Breast Adenocarcinoma ◽  
Human Breast ◽  
Human Breast Adenocarcinoma ◽  
Adenocarcinoma Cells

Enhancement of docetaxel-treated MCF-7 cell death by 900-MHz radiation

2013 ◽  
Vol 8 (4) ◽  
pp. 357-365
Author(s):  
Marianna Trebuňová ◽  
Galina Laputková ◽  
Imrich Géci ◽  
Igor Andrašina ◽  
Ján Sabo
Keyword(s):  
Cell Culture ◽  
Cell Death ◽  
Electromagnetic Field ◽  
High Frequency ◽  
Input Power ◽  
Breast Adenocarcinoma ◽  
Human Breast ◽  
Human Breast Adenocarcinoma ◽  
High Frequency Electromagnetic Field ◽  
Mcf 7

AbstractThe aim of the study was to investigate the effect of high-frequency electromagnetic field of 900 MHz at 8 W input power on metabolic activity of human breast adenocarcinoma MCF-7 cells. With the aid of the colorimetric MTT assay, it was shown that there is significant change in cell culture survival exposed to docetaxel in field-free conditions in comparison with cells treated with docetaxel simultaneously exposed to high-frequency electromagnetic field.

Uranium Stimulates Estrogen-Responsive Gene Expression in Stably Transfected T47D Human Breast Adenocarcinoma Cells.

2008 ◽  
Vol 78 (Suppl_1) ◽  
pp. 96-96
Author(s):  
Michael J. Hendrix ◽  
Kevin D. Sullivan ◽  
Jeff W. Henrikson ◽  
Samantha K. Kemper ◽  
Stefanie Raymond-Whish ◽  
...  
Keyword(s):  
Gene Expression ◽  
Breast Adenocarcinoma ◽  
Human Breast ◽  
Human Breast Adenocarcinoma ◽  
Adenocarcinoma Cells ◽  
Estrogen Responsive Gene ◽  
Responsive Gene
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