Early motoneuron formation in the cervical spinal cord of the mouse: An electron microscopic, serial section analysis

1978 ◽  
Vol 177 (4) ◽  
pp. 611-633 ◽  
Author(s):  
Lee E. Wentworth ◽  
James W. Hinds
Keyword(s):  
Spinal Cord ◽  
Serial Section ◽  
Cervical Spinal Cord ◽  
Electron Microscopic ◽  
Section Analysis

Giant cell ependymoma of the spinal cord

2004 ◽  
Vol 100 (1) ◽  
pp. 75-79 ◽  
Author(s):  
Daryl R. Fourney ◽  
Abdolreza Siadati ◽  
Janet M. Bruner ◽  
Ziya L. Gokaslan ◽  
Laurence D. Rhines
Keyword(s):  
Spinal Cord ◽  
Giant Cell ◽  
Cervical Spinal Cord ◽  
Giant Cells ◽  
Electron Microscopic ◽  
Content Type ◽  
First Case ◽  
Microscopic Features ◽  
Cell Variant ◽  
Well Differentiated

✓ Several rare histological variants of ependymoma have been described. The authors report on a patient in whom cervical spinal cord astrocytoma was originally diagnosed after evaluation of a limited biopsy specimen. More abundant tissue obtained during gross-total resection included areas of well-differentiated ependymoma. The histological features of the tumor were extremely unusual, with a major component of pleomorphic giant cells. Its histological, immunohistochemical, and electron microscopic features, however, were consistent with ependymoma. Only two cases of terminal filum and two of supratentorial giant cell variant of ependymoma have been reported. To the authors' knowledge, this represents the first case of giant cell ependymoma of the spinal cord. The clinical significance is the potential for misdiagnosis with anaplastic (gemistocytic) astrocytoma, especially in cases in whom limited biopsy samples have been obtained.

scholarly journals Spontaneous Frenkelia Infection in a Laboratory-Reared Rat

1976 ◽  
Vol 13 (5) ◽  
pp. 337-342 ◽  
Author(s):  
D. W. Hayden ◽  
N. W. King ◽  
A. S. K. Murthy
Keyword(s):  
Spinal Cord ◽  
Mononuclear Cell ◽  
Cervical Spinal Cord ◽  
Wild Rodents ◽  
Electron Microscopic ◽  
Microscopic Features ◽  
Thin Walled ◽  
Mononuclear Cell Infiltrates ◽  
The Brain

Numerous, lobulated, thin-walled protozoan cysts were found in the brain and cervical spinal cord of a male Fischer rat with granulomatous encephalitis. The cysts were compartmented, 470–1000 μm in diameter, and packed with crescent-shaped organisms. Light- and electron-microscopic features of the organism were characteristic of the protozoan Frenkelia, a parasite usually found in the brain of wild rodents. Many cysts were replaced by granulomas, whereas others elicited no inflammation. Perivascular and meningeal mononuclear cell infiltrates and gliosis were common.

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