The early development of the motor cells and columns in the spinal cord of the sheep

1943 ◽  
Vol 78 (1) ◽  
pp. 1-27 ◽  
Author(s):  
Donald H. Barron
Keyword(s):  
Spinal Cord ◽  
Early Development ◽  
Motor Cells

Mouse Cdx-1 expression during gastrulation

Development ◽  
1993 ◽  
Vol 117 (1) ◽  
pp. 191-203 ◽  
Author(s):  
B.I. Meyer ◽  
P. Gruss
Keyword(s):  
Spinal Cord ◽  
Expression Pattern ◽  
Early Development ◽  
Primitive Streak ◽  
Embryonic Axes ◽  
Specific Expression ◽  
Limb Buds ◽  
Process Formation ◽  
Spinal Cord Level ◽  
Anterior Posterior

We describe the expression pattern of the mouse Cdx-1 gene during early development, examined by both RNA and protein analyses. Cdx-1 expression began with the onset of the head process formation (day 7.5) in ectodermal and mesodermal cells of the primitive streak. Expression extended initially to the middle of the prospective hindbrain and subsequently regressed caudad to the spinal cord level by day 9.5. The mesoderm-specific expression was detected in the first somites and could be followed during their differentiation to the myotome of the dorsal somitic edge by day 12. The developing limb buds and the mesonephros exhibited expression up to day 12. No signal could be detected in notochordal cells and cells of the definitive endoderm. Thus, Cdx-1 is expressed during gastrulation when anterior-posterior positional values are established along the embryonic axes. Furthermore, the expression correlates with the formation of segmented tissue in the posterior hindbrain, the spinal cord and structures like the mesonephros.

scholarly journals Dr. med. V. Dzerzhinskiy. Clinical observation in the field of neuropathology. Moscow. 1912 V. I.

1912 ◽  
Vol XIX (3) ◽  
pp. 663-664
Author(s):  
A. Favorskii
Keyword(s):  
Spinal Cord ◽  
Lumbar Puncture ◽  
Special Interest ◽  
Clinical Observation ◽  
Short Form ◽  
Short History ◽  
Scientific Thought ◽  
Lower Back ◽  
History Of ◽  
Motor Cells

In view of giving clinical material for the study of various forms of chorea, poliomyelitis and polyoncephalitis, the author used for this purpose the clinical histories of diseases of the Moscow Clinic of Nervous Diseases (director - prof. V. K. Rot). The entire work is divided into 7 chapters and contains in a short form 35 histories of diseases. In each chapter, the literature of the corresponding painful form is first given, and then its cases are described. Among them there are such not often encountered cases, such as syphilitic poliomyelitis and poliomyelitis on the soil of smallpox. In general, the work is of a lot of special interest for a neuropathologist and, together with it, introduces the direction of scientific thought, which has a place in the Moscow Nervous Clinic. With all the merits of the published work, one cannot remain silent about some of its shortcomings, in our opinion, one can reproach the author for his desire to give a short history of illness. In the study of clinical forms, brevity can quickly interfere with the understanding of the process underlying a particular nosological unit. For example, we will point to the observations of the XI and XV-e. It is not clear to the reader whether the attention of the study was drawn to the existence of pain in patients with pressure on the nerve trunks or nerves, but between the two this in our eyes may have a meaning for the purity of the diagnosis. It is unclear, further, why the author does not provide data on lumbar puncture and Wassermann's reaction in the cases where this could have been done (obs. XV). In the cases cited from the literature, the same excessive brevity is visible. So on p. 183 it says about anesthesia I and II in n. trigemini, but which side? Further, it is hardly advisable to use such expressions: (p. 58) degeneration of the posterior pillars from the lower back (?) To the cerebellum, or (p. 89): with tabes, not only the motor cells of the spinal cord, but also in the legs brain ". It would be desirable to avoid the term so-called. muscle sensitivity where there is a rumor about "muscle feelings".

Microtubule-associated protein 1a is involved in the early development of the rat spinal cord

1998 ◽  
Vol 246 (2) ◽  
pp. 81-84 ◽  
Author(s):  
M. Oudega ◽  
F. Touri ◽  
M.G.M. Deenen ◽  
B.M. Riederer ◽  
E. Marani
Keyword(s):  
Spinal Cord ◽  
Early Development ◽  
Rat Spinal Cord

scholarly journals Early development of glycine- and GABA-mediated synapses in rat spinal cord

1992 ◽  
Vol 12 (10) ◽  
pp. 3935-3945 ◽  
Author(s):  
WL Wu ◽  
L Ziskind-Conhaim ◽  
MA Sweet
Keyword(s):  
Spinal Cord ◽  
Early Development ◽  
Rat Spinal Cord

scholarly journals A comparative study of the grey and white matter of the motor cell groups, and of the spinal accessory nerve, in the spinal cord of the porpoise ( Phocœna communis )

1903 ◽  
Vol 71 (467-476) ◽  
pp. 444-445
Keyword(s):  
Spinal Cord ◽  
White Matter ◽  
Comparative Study ◽  
Human Subject ◽  
Comparative Method ◽  
Spinal Accessory Nerve ◽  
Accessory Nerve ◽  
Spinal Accessory ◽  
Cell Groups ◽  
Motor Cells

Recent advances in our knowledge of the arrangement of the motor cells in the anterior cornua of the spinal cord of man have been made almost entirely by the study of the changes produced in these cells by the division or removal of limbs or parts of limbs in the human subject, and very little has, as yet, been done to elucidate this subject by the comparative method of investigation.

Segmental pattern of development of the hindbrain and spinal cord of the zebrafish embryo

Development ◽  
1988 ◽  
Vol 103 (1) ◽  
pp. 49-58 ◽  
Author(s):  
E. Hanneman ◽  
B. Trevarrow ◽  
W.K. Metcalfe ◽  
C.B. Kimmel ◽  
M. Westerfield
Keyword(s):  
Spinal Cord ◽  
Monoclonal Antibody ◽  
Early Development ◽  
Zebrafish Embryo ◽  
Single Cells ◽  
Acetylcholinesterase Activity ◽  
Zebrafish Embryos ◽  
Small Clusters ◽  
Spinal Motoneurones

In the ventral hindbrain and spinal cord of zebrafish embryos, the first neurones that can be identified appear as single cells or small clusters of cells, distributed periodically at intervals equal to the length of a somite. In the hindbrain, a series of neuromeres of corresponding length is present, and the earliest neurones are located in the centres of each neuromere. Young neurones within both the hindbrain and spinal cord were identified in live embryos using Nomarski optics, and histochemically by labelling for acetylcholinesterase activity and expression of an antigen recognized by the monoclonal antibody zn-1. Among them are individually identified hindbrain reticulospinal neurones and spinal motoneurones. These observations suggest that early development in these regions of the CNS reflects a common segmental pattern. Subsequently, as more neurones differentiate, the initially similar patterning of the cells in these two regions diverges. A continuous longitudinal column of developing neurones appears in the spinal cord, whereas an alternating series of large and small clusters of neurones is present in the hindbrain.

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