scholarly journals Prostate cancer and the added burden of COVID‐19 in sub‐Saharan Africa: Rethinking regional priorities for responsive and data‐driven cancer control programs

Cancer ◽  
2021 ◽  
Author(s):  
Elochukwu F. Ezenwankwo ◽  
Chukwudi A. Nnaji
Keyword(s):  
Prostate Cancer ◽  
Cancer Control ◽  
Sub Saharan Africa ◽  
Data Driven ◽  
Control Programs ◽  
Sub Saharan

The big three versus NTDs - finding common purpose.

2021 ◽  
pp. 92-102
Author(s):  
Alan Fenwick ◽  
Wendie Norris ◽  
Becky McCall
Keyword(s):  
Sub Saharan Africa ◽  
Control Programs ◽  
Humanitarian Response ◽  
Common Purpose ◽  
Sub Saharan ◽  
First Time ◽  
National Control ◽  
Leprosy Control ◽  
Onchocerciasis Control

Abstract Even so, no country in sub-Saharan Africa before 2000 had national control programs for any of the seven programs, with the exception of cervical cancer. Onchocerciasis is the target of the Africa Program for Onchocerciasis Control (APOC) with the help of many NGOs organisation using the drug mectizan (ivermectin). The use of drug financing at APOC is revolutionary. They had, for the first time, established as a viable concept with leprosy control programs, and now, with APOC, demonstrated that pharmaceutical companies can and will reuse a drug and treat it as part of a humanitarian response. This book chapter focused on repurposing drugs against schistosomiasis.

scholarly journals Management of Advanced and Metastatic Prostate Cancer: A Need for a Sub-Saharan Guideline

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Ayun Cassell ◽  
Bashir Yunusa ◽  
Mohamed Jalloh ◽  
Medina Ndoye ◽  
Mouhamadou M. Mbodji ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Deprivation Therapy ◽  
Metastatic Prostate Cancer ◽  
Cost Effective ◽  
Androgen Deprivation ◽  
Sub Saharan Africa ◽  
International Agency ◽  
Castrate Resistant Prostate Cancer ◽  
Sub Saharan ◽  
Castrate Resistant

The estimated incidence rate of prostate cancer in Africa was 22.0/100,000 in 2016. The International Agency for Research on Cancer (IARC) has cited prostate cancer as a growing health threat in Africa with approximated 28,006 deaths in 2010 and estimated 57,048 deaths in 2030. The exact incidence of advanced and metastatic prostate cancer is not known in sub-Saharan Africa. Hospital-based reports from the region have shown a rising trend with most patients presenting with advanced or metastatic disease. The management of advanced and metastatic prostate cancer is challenging. The available international guidelines may not be cost-effective for an African population. The most efficient approach in the region has been surgical castration by bilateral orchidectomy or pulpectomy. Medical androgen deprivation therapy is expensive and may not be available. Patients with metastatic castrate-resistant prostate cancer tend to be palliated due to the absence or cost of chemotherapy or second-line androgen deprivation therapy in most of Africa. A cost-effective guideline for developing nations to address the rising burden of advanced prostate cancer is warranted at this moment.

Abstract 2410: Development of a custom genotyping platform and genetic prediction of prostate cancer risks in sub-Saharan Africa

2019 ◽  
Author(s):  
Joseph Lachance ◽  
Maxine Harlemon ◽  
Paidamoyo Kachambwa ◽  
Olabode Ajayi ◽  
Michelle Kim ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Sub Saharan Africa ◽  
Cancer Risks ◽  
Genetic Prediction ◽  
Genotyping Platform ◽  
Sub Saharan

Abstract 2410: Development of a custom genotyping platform and genetic prediction of prostate cancer risks in sub-Saharan Africa

2019 ◽  
Author(s):  
Joseph Lachance ◽  
Maxine Harlemon ◽  
Paidamoyo Kachambwa ◽  
Olabode Ajayi ◽  
Michelle Kim ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Sub Saharan Africa ◽  
Cancer Risks ◽  
Genetic Prediction ◽  
Genotyping Platform ◽  
Sub Saharan

scholarly journals Schistosomiasis and cancer: Experience from a zonal hospital in Tanzania and opportunities for prevention

2020 ◽  
Vol 2020 (5) ◽  
Author(s):  
Jay Lodhia ◽  
Alex Mremi ◽  
Jeremia J Pyuza ◽  
Nicholas Bartholomeo ◽  
Ayesiga M Herman
Keyword(s):  
Case Series ◽  
Cancer Control ◽  
Public Health Problem ◽  
African Countries ◽  
Control Programs ◽  
Treatment Services ◽  
Resource Setting ◽  
Low Resource Setting ◽  
Sub Saharan ◽  
Cancer Experience

Abstract Schistosomiasis infection is endemic in many parts of Tanzania. The morbidity due to Schistosomiasis and its association with cancer remains to be of great concern and poses greater challenge that needs to be assessed. Cancer is an increasing public health problem in most sub-Saharan African countries, and yet, cancer control programs and the provision of early detection and treatment services are limited despite this increasing burden. This article aims to discuss case series of patients diagnosed with urinary bladder, prostate and colorectal cancer together with Schistosoma infection. We further highlight the opportunities for combating new Schistosomiasis infection, a potential to reduce its oncological complications particularly in low-resource setting.

scholarly journals Presentation, patterns of care, and outcomes of patients with prostate cancer in sub‐Saharan Africa: A population‐based registry study

Cancer ◽  
2021 ◽  
Author(s):  
Tobias Paul Seraphin ◽  
Walburga Yvonne Joko‐Fru ◽  
Lucia Hämmerl ◽  
Mirko Griesel ◽  
Nikolaus Christian Simon Mezger ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Population Based ◽  
Patterns Of Care ◽  
Sub Saharan Africa ◽  
Registry Study ◽  
Sub Saharan ◽  
Population Based Registry

scholarly journals Infectious disease, development, and climate change: a scenario analysis

2007 ◽  
Vol 12 (5) ◽  
pp. 687-706 ◽  
Author(s):  
RICHARD S.J. TOL ◽  
KRISTIE L. EBI ◽  
GARY W. YOHE
Keyword(s):  
Climate Change ◽  
Infectious Disease ◽  
Infant Mortality ◽  
Infectious Diseases ◽  
Sub Saharan Africa ◽  
Absolute Poverty ◽  
Control Programs ◽  
Short Run ◽  
Sub Saharan

We study the effects of development and climate change on infectious diseases in Sub-Saharan Africa. Infant mortality and infectious disease are closely related, but there are better data for the former. In an international cross-section, per capita income, literacy, and absolute poverty significantly affect infant mortality. We use scenarios of these three determinants and of climate change to project the future incidence of malaria, assuming it to change proportionally to infant mortality. Malaria deaths will first increase, because of population growth and climate change, but then fall, because of development. This pattern is robust to the choice of scenario, parameters, and starting conditions; and it holds for diarrhoea, schistosomiasis, and dengue fever as well. However, the timing and level of the mortality peak is very sensitive to assumptions. Climate change is important in the medium term, but dominated in the long term by development. As climate can only be changed with a substantial delay, development is the preferred strategy to reduce infectious diseases even if they are exacerbated by climate change. Development can, in particular, support the needed strengthening of disease control programs in the short run and thereby increase the capacity to cope with projected increases in infectious diseases over the medium to long term. This conclusion must, however, be viewed with caution, because development, even of the sort envisioned in the underlying socio-economic scenarios, is by no means certain.

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