scholarly journals Socioeconomics, race, and ethnicity in childhood cancer survival: Accessing and addressing root causes of disparities

Cancer ◽  
2018 ◽  
Vol 124 (20) ◽  
pp. 3975-3978 ◽  
Author(s):  
Meryl D. Colton ◽  
Makenzie Hawkins ◽  
DeLayna Goulding ◽  
Myles Cockburn ◽  
Adam L. Green
Keyword(s):  
Childhood Cancer ◽  
Race And Ethnicity ◽  
Cancer Survival ◽  
Childhood Cancer Survival

Childhood cancer survival in Europe

2001 ◽  
Vol 37 (6) ◽  
pp. 810-816 ◽  
Author(s):  
B. Terracini ◽  
J.-W. Coebergh ◽  
G. Gatta ◽  
C. Magnani ◽  
C. Stiller ◽  
...  
Keyword(s):  
Childhood Cancer ◽  
Cancer Survival ◽  
Childhood Cancer Survival

scholarly journals Improvement in childhood cancer survival in Lithuania over three decades

2020 ◽  
Vol 27 (1) ◽  
pp. 1-9
Author(s):  
Jelena Rascon ◽  
Giedrė Smailytė
Keyword(s):  
Childhood Cancer ◽  
Cancer Survival ◽  
Survival Rates ◽  
Population Based ◽  
Early Years ◽  
University Hospital ◽  
Entire Cohort ◽  
Background Population ◽  
Childhood Cancer Survival

Background. Population-based EUROCARE-5 studies demonstrated that childhood cancer survival rates in Lithuania were 10–20% lower than the European mean. We aimed to analyse the change in the outcome of treatment of paediatric malignancies in Lithuania over 30 years. Methods. A single-centre retrospective analysis of children below 18 years of age treated for cancer at Vilnius University Hospital Santaros Klinikos between 1982 and 2011 was carried out. The minimal requirement of 5-year follow-up after diagnosis was specified for survival estimation. The vital status was assessed using data from the population-based Lithuanian Cancer Registry. To evaluate changes over time, the entire cohort was split into three groups according to the time of diagnosis: 1982–1991, 1992–2001, and 2002–2011. Results. A total of 1268 children met the inclusion criteria. The shortest median follow-up was 8.9 (IQR 6.4–11.5) years for patients treated in the third decade. The 5-year overall survival of the entire cohort increased from 37.3% (95% CI 30.2–44.3) in 1982–1991 to 70.7% (95% CI 66.4–74.1) in 2002–2011 (p < 0.0001). The same trend was evident when calculated separately for leukaemia (p < 0.0001), lymphoma (p < 0.0005), and solid tumours (p < 0.004). The percentage of cure rose from zero in the early years of the period analysed to 80% in 2010 and 2011. The improvement in the treatment outcome was attributable to the reduction of treatment-related mortality from 45.8% in 1982–1991 to 12.4% in 2002–2011 and disease recurrence from 30.4% to 19.6% for the same periods, respectively. Conclusions. Significant progress in the cure rate of children treated for cancer at our institution was observed over 30 years. Collaborative national and international clinical and research efforts are crucial to ensure further advances in care and cure.

scholarly journals Global childhood cancer survival estimates and priority-setting: a simulation-based analysis

2019 ◽  
Vol 20 (7) ◽  
pp. 972-983 ◽  
Author(s):  
Zachary J Ward ◽  
Jennifer M Yeh ◽  
Nickhill Bhakta ◽  
A Lindsay Frazier ◽  
Fabio Girardi ◽  
...  
Keyword(s):  
Childhood Cancer ◽  
Priority Setting ◽  
Cancer Survival ◽  
Simulation Based ◽  
Childhood Cancer Survival

scholarly journals Childhood cancer survival in Europe and the United States

Cancer ◽  
2002 ◽  
Vol 95 (8) ◽  
pp. 1767-1772 ◽  
Author(s):  
Gemma Gatta ◽  
Riccardo Capocaccia ◽  
Michel P. Coleman ◽  
Lynn A. Gloeckler Ries ◽  
Franco Berrino
Keyword(s):  
United States ◽  
Childhood Cancer ◽  
Cancer Survival ◽  
The United States ◽  
Childhood Cancer Survival

Racial/ethnic disparities in childhood cancer survival in the United States: Mediation effects of health insurance coverage and area-level social deprivation.

2019 ◽  
Vol 37 (27_suppl) ◽  
pp. 143-143
Author(s):  
Jingxuan Zhao ◽  
Xuesong Han ◽  
Zhiyuan Zheng ◽  
Leticia Maciel Nogueira ◽  
Paul C. Nathan ◽  
...  
Keyword(s):  
United States ◽  
Health Insurance ◽  
Childhood Cancer ◽  
Cancer Survival ◽  
Social Deprivation ◽  
Insurance Coverage ◽  
Ethnic Disparities ◽  
The United States ◽  
Childhood Cancer Survival ◽  
Racial Ethnic

143 Background: Childhood cancer survival varies by race/ethnicity in the United States. This study evaluated the impact of potentially modifiable characteristics - health insurance and area-level social deprivation - on racial/ethnic disparities in childhood cancer survival nationwide. Methods: We identified 65,113 childhood cancer patients aged < 18 years newly diagnosed with any of 10 common cancer types (e.g. central nervous system (CNS) neoplasms, acute lymphoblastic leukemia (ALL), Hodgkin lymphoma) from the 2004-2014 National Cancer Database. Cox proportional hazard models were used to compare survival probabilities by race and ethnicity (non-Hispanic white (NHW) vs non-Hispanic black (NHB), Hispanic, and non-Hispanic other (NH other)) for each cancer type. We conducted mediation analyses by the mma R package to evaluate the racial/ethnic survival disparities mediated by health insurance (private, Medicaid, and uninsured) and social deprivation index (SDI) quartile. SDI is a composite measure of deprivation based on seven characteristics (e.g. income, education, employment). Results: Compared to NHW, worse survival were observed for NHB (HR (hazard ratio): 1.4, 95% CI: 1.3-1.5), Hispanic (HR: 1.2, 95% CI: 1.1-1.2), and NH other (HR: 1.2, 95% CI: 1.1-1.3) for all cancer sites combined after adjusting for sociodemographic characteristics other than health insurance and SDI. Health insurance explained 20% of the survival disparities and SDI explained 19% of the disparity between NHB vs NHW; health insurance explained 48% of the survival disparities and SDI explained 45% of the disparity between Hispanic vs NHW. For ALL, health insurance significantly explained 15% and 18% of the survival disparities between NHB and Hispanic vs NHW, respectively. SDI significantly explained 19% and 31% of the disparities, respectively. Conclusions: Health insurance and SDI mediated racial/ethnic survival disparities for several childhood cancers. Expanding insurance coverage and improving healthcare access in disadvantaged areas may effectively reduce disparities for these cancer sites.

Childhood cancer survival in France, 2000–2008

2014 ◽  
Vol 23 (5) ◽  
pp. 449-457 ◽  
Author(s):  
Brigitte Lacour ◽  
Stéphanie Goujon ◽  
Sandra Guissou ◽  
Aurélie Guyot-Goubin ◽  
Solène Desmée ◽  
...  
Keyword(s):  
Childhood Cancer ◽  
Cancer Survival ◽  
Childhood Cancer Survival
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