scholarly journals Randomized controlled trial of irinotecan drug-eluting beads with simultaneous FOLFOX and bevacizumab for patients with unresectable colorectal liver-limited metastasis

Cancer ◽  
2015 ◽  
Vol 121 (20) ◽  
pp. 3649-3658 ◽  
Author(s):  
Robert C. G. Martin ◽  
Charles R. Scoggins ◽  
Marshall Schreeder ◽  
William S. Rilling ◽  
Christopher J. Laing ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Drug Eluting Beads ◽  
Drug Eluting ◽  
Limited Metastasis

A prospective randomized controlled trial of selective transarterial chemoembolization using drug-eluting beads loaded with epirubicin versus selective conventional transarterial chemoembolization using epirubicin-lipiodol for hepatocellular carcinoma: The JIVROSG-1302 PRESIDENT study.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. 4518-4518 ◽  
Author(s):  
Masafumi Ikeda ◽  
Yoshitaka Inaba ◽  
Toshihiro Tanaka ◽  
Shunsuke Sugawara ◽  
Yoshihisa Kodama ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Adverse Events ◽  
Transarterial Chemoembolization ◽  
Controlled Trial ◽  
Tumor Control ◽  
Serum Total Bilirubin ◽  
Randomized Controlled ◽  
Tace Group ◽  
Drug Eluting Beads ◽  
Drug Eluting

4518 Background: Transarterial chemoembolization (TACE) with selective catheterization into the segmental or subsegmental hepatic arteries supplying HCC is often performed to achieve the complete local control of HCC in the patients with a limited number of small sized nodules. To clarify which of TACE with drug-eluting beads loaded with epirubicin (DEB-TACE) or conventional TACE with epirubicin-lipiodol (cTACE) can achieve the complete response (CR) more frequently, we performed a randomized controlled trial of DEB-TACE vs. cTACE. Methods: Between March 2016 and May 2019, unresectable HCC patients with Child-Pugh class A or B who were scheduled to receive selective TACE were randomly assigned 1:1 to the DEB-TACE group and the cTACE group. The primary endpoint was the CR rate at 3 months, and the secondary endpoints were the CR rate at 1 month and rate of adverse events (AEs). The response and AEs were assessed according to the modified RECIST by an independent review committee and the National Cancer Institute Common Terminology Criteria for Adverse Events, version 4.0., respectively. Results: A total of 200 patients (DEB-TACE, 99 patients; cTACE 101 patients) were enrolled from 22 Japanese institutions. The patient characteristics were well-balanced between the two groups. The median number of tumors was one in both groups and the median tumor size was 20.0 mm in the DEB-TACE group and 20.5 mm in the cTACE group. The table shows the CR rates and frequencies of AEs. The CR rates of cTACE at 3 and 1 months were significantly higher than those of DEB-TACE. The frequency of AEs (all grades), including pyrexia, malaise, increased serum total bilirubin (T-Bil) and increased serum alanine transaminase (ALT), was significantly higher in the cTACE group than in the DEB-TACE group. Conclusions: Selective cTACE appeared to have greater efficacy for local tumor control as compared to selective DEB-TACE, however, the frequencies of post-embolization syndromes were higher in the cTACE group than in the DEB-TACE group. Clinical trial information: UMIN000021250 . [Table: see text]

scholarly journals Randomized Controlled Trial of Acotec Drug-Eluting Balloon Versus Plain Balloon for Below-the-Knee Angioplasty

2020 ◽  
Vol 13 (19) ◽  
pp. 2277-2286 ◽  
Author(s):  
Francesco Liistro ◽  
Paolo Angioli ◽  
Giorgio Ventoruzzo ◽  
Kenneth Ducci ◽  
Matteo Rocco Reccia ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Below The Knee ◽  
Drug Eluting ◽  
Drug Eluting Balloon

Ethmoid Drug-Eluting Catheter for Nasosinusal Polyposis: Results after a Randomized Controlled Trial

2014 ◽  
Vol 151 (1_suppl) ◽  
pp. P119-P119
Author(s):  
Guillermo Plaza ◽  
Elizabeth A. Espitia ◽  
Estefanía Hernández-García ◽  
Gustavo Eisenberg ◽  
Victoria García-Peces ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Drug Eluting

scholarly journals XLIMus drug eluting stent: A randomIzed controlled Trial to assess endothelialization. The XLIMIT trial

2019 ◽  
Vol 23 ◽  
pp. 100363
Author(s):  
Luca Testa ◽  
Gaetano Pero ◽  
Mario Bollati ◽  
Matteo Casenghi ◽  
Antonio Popolo Rubbio ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Drug Eluting Stent ◽  
Randomized Controlled ◽  
Drug Eluting
Sign in / Sign up

Export Citation Format

Share Document