Long-term regional control and survival in patients with “low-risk,” early stage oral tongue cancer managed by partial glossectomy and neck dissection without postoperative radiation

Cancer ◽  
2012 ◽  
Vol 119 (6) ◽  
pp. 1168-1176 ◽  
Author(s):  
Ian Ganly ◽  
David Goldstein ◽  
Diane L. Carlson ◽  
Snehal G. Patel ◽  
Brian O'Sullivan ◽  
...  
Keyword(s):  
Neck Dissection ◽  
Tongue Cancer ◽  
Early Stage ◽  
Low Risk ◽  
Postoperative Radiation ◽  
Oral Tongue ◽  
Regional Control ◽  
Oral Tongue Cancer ◽  
Partial Glossectomy

scholarly journals Improving Risk Stratification of Early Oral Tongue Cancer with TNM-Immune (TNM-I) Staging System

Cancers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 3235
Author(s):  
Alhadi Almangush ◽  
Ibrahim O. Bello ◽  
Ilkka Heikkinen ◽  
Jaana Hagström ◽  
Caj Haglund ◽  
...  
Keyword(s):  
Overall Survival ◽  
Tongue Cancer ◽  
Early Stage ◽  
Disease Free Survival ◽  
Tumor Infiltrating Lymphocytes ◽  
Staging System ◽  
Oral Tongue ◽  
Oral Tongue Cancer ◽  
Important Player ◽  
Infiltrating Lymphocytes

Although patients with early-stage oral tongue squamous cell carcinoma (OTSCC) show better survival than those with advanced disease, there is still a number of early-stage cases who will suffer from recurrence, cancer-related mortality and worse overall survival. Incorporation of an immune descriptive factor in the staging system can aid in improving risk assessment of early OTSCC. A total of 290 cases of early-stage OTSCC re-classified according to the American Joint Committee on Cancer (AJCC 8) staging were included in this study. Scores of tumor-infiltrating lymphocytes (TILs) were divided as low or high and incorporated in TNM AJCC 8 to form our proposed TNM-Immune system. Using AJCC 8, there were no significant differences in survival between T1 and T2 tumors (p > 0.05). Our proposed TNM-Immune staging system allowed for significant discrimination in risk between tumors of T1N0M0-Immune vs. T2N0M0-Immune. The latter associated with a worse overall survival with hazard ratio (HR) of 2.87 (95% CI 1.92–4.28; p < 0.001); HR of 2.41 (95% CI 1.26–4.60; p = 0.008) for disease-specific survival; and HR of 1.97 (95% CI 1.13–3.43; p = 0.017) for disease-free survival. The TNM-Immune staging system showed a powerful ability to identify cases with worse survival. The immune response is an important player which can be assessed by evaluating TILs, and it can be implemented in the staging criteria of early OTSCC. TNM-Immune staging forms a step towards a more personalized classification of early OTSCC.

scholarly journals Depth of invasion, tumor budding, and worst pattern of invasion: Prognostic indicators in early‐stage oral tongue cancer

Head & Neck ◽  
2013 ◽  
Vol 36 (6) ◽  
pp. 811-818 ◽  
Author(s):  
Alhadi Almangush ◽  
Ibrahim O. Bello ◽  
Harri Keski–Säntti ◽  
Laura K. Mäkinen ◽  
Joonas H. Kauppila ◽  
...  
Keyword(s):  
Tongue Cancer ◽  
Early Stage ◽  
Tumor Budding ◽  
Prognostic Indicators ◽  
Depth Of Invasion ◽  
Oral Tongue ◽  
Oral Tongue Cancer ◽  
Pattern Of Invasion ◽  
Worst Pattern Of Invasion

A novel tumor: Specimen index for assessing adequacy of resection in early stage oral tongue cancer

Oral Oncology ◽  
2014 ◽  
Vol 50 (3) ◽  
pp. 213-220 ◽  
Author(s):  
Pablo H. Montero ◽  
Frank L. Palmer ◽  
Andrew G. Shuman ◽  
Purvi D. Patel ◽  
Jay O. Boyle ◽  
...  
Keyword(s):  
Tongue Cancer ◽  
Early Stage ◽  
Oral Tongue ◽  
Tumor Specimen ◽  
Oral Tongue Cancer

Robot-Assisted Selective Neck Dissection via Modified Face-lift Approach for Early Oral Tongue Cancer: A Video Demonstration

2011 ◽  
Vol 19 (4) ◽  
pp. 1334-1335 ◽  
Author(s):  
Yoon Woo Koh ◽  
Woong Youn Chung ◽  
Hyun Jun Hong ◽  
So-Yoon Lee ◽  
Won Shik Kim ◽  
...  
Keyword(s):  
Neck Dissection ◽  
Tongue Cancer ◽  
Selective Neck Dissection ◽  
Oral Tongue ◽  
Robot Assisted ◽  
Face Lift ◽  
Oral Tongue Cancer ◽  
Video Demonstration

A simple novel prognostic model for early stage oral tongue cancer

2015 ◽  
Vol 44 (2) ◽  
pp. 143-150 ◽  
Author(s):  
A. Almangush ◽  
R.D. Coletta ◽  
I.O. Bello ◽  
C. Bitu ◽  
H. Keski-Säntti ◽  
...  
Keyword(s):  
Prognostic Model ◽  
Tongue Cancer ◽  
Early Stage ◽  
Oral Tongue ◽  
Oral Tongue Cancer

scholarly journals Long-term disease-free survival in surgically-resected oral tongue cancer: a 10-year retrospective study

2019 ◽  
Vol 39 (2) ◽  
pp. 84-91 ◽  
Author(s):  
A. Marra ◽  
M. Violati ◽  
F. Broggio ◽  
C. Codecà ◽  
M. Blasi ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Tongue Cancer ◽  
Disease Free Survival ◽  
Oral Tongue ◽  
Free Survival ◽  
Oral Tongue Cancer ◽  
Disease Free

SU-E-T-887: Cyberknife Treatment for Early Stage Oral Tongue Cancer - Feasibility Study

2011 ◽  
Vol 38 (6Part24) ◽  
pp. 3695-3696
Author(s):  
J Fan ◽  
E Fourka ◽  
S Hayes ◽  
L Jin ◽  
L Wang ◽  
...  
Keyword(s):  
Feasibility Study ◽  
Tongue Cancer ◽  
Early Stage ◽  
Oral Tongue ◽  
Oral Tongue Cancer
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