scholarly journals Helicobacter pyloriinduces promoter methylation of E-cadherin via interleukin-1β activation of nitric oxide production in gastric cancer cells

Cancer ◽  
2012 ◽  
Vol 118 (20) ◽  
pp. 4969-4980 ◽  
Author(s):  
Fung-Yu Huang ◽  
Annie On-On Chan ◽  
Asif Rashid ◽  
Danny Ka-Ho Wong ◽  
Chi-Hin Cho ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Gastric Cancer ◽  
Cancer Cells ◽  
Promoter Methylation ◽  
Interleukin 1Β ◽  
Nitric Oxide Production ◽  
Gastric Cancer Cells ◽  
Oxide Production ◽  
E Cadherin

scholarly journals Quercetin Attenuates Nuclear Factor-κB Activation and Nitric Oxide Production in Interleukin-1β–Activated Rat Hepatocytes

2005 ◽  
Vol 135 (6) ◽  
pp. 1359-1365 ◽  
Author(s):  
Susana Martínez-Flórez ◽  
Belén Gutiérrez-Fernández ◽  
Sonia Sánchez-Campos ◽  
Javier González-Gallego ◽  
María J. Tuñón
Keyword(s):  
Nitric Oxide ◽  
Rat Hepatocytes ◽  
Nuclear Factor Κb ◽  
Interleukin 1Β ◽  
Nitric Oxide Production ◽  
Nuclear Factor ◽  
Oxide Production

Interleukin 10 inhibits insulin release from and nitric oxide production in rat pancreatic islets

1996 ◽  
Vol 135 (3) ◽  
pp. 374-378 ◽  
Author(s):  
Renato Laffranchi ◽  
Giatgen A Spinas
Keyword(s):  
Nitric Oxide ◽  
Pancreatic Islets ◽  
Insulin Release ◽  
Interleukin 10 ◽  
Interleukin 1Β ◽  
Nitric Oxide Production ◽  
Β Cell ◽  
Cell Dysfunction ◽  
Rat Pancreatic Islets ◽  
Oxide Production

Laffranchi R, Spinas GA. Interleukin 10 inhibits insulin release from and nitric oxide production in rat pancreatic islets. Eur J Endocrinol 1996;135:374–8. ISSN 0804–4643 Interleukin 10 was found to prevent cytokine-induced nitric oxide production in murine macrophages. Because, in rat islets, interleukin 1β induces β-cell dysfunction, mainly due to overproduction of nitric oxide, we studied if this effect could be counteracted by interleukin 10. Rat pancreatic islets were cultured for 24 h in the presence or absence of 0.02–20 ng/ml recombinant human interleukin 10. Interleukin 10 dose-dependently inhibited insulin secretion with maximal inhibition (27 ±4%, p < 0.05) at 2 ng/ml without impairment of islet cell viability. However, incubation of pancreatic islets with interleukin 10 resulted in a 61.5% decrease of nitric oxide production. Co-incubation of islets with interleukin 10 (2 ng/ml) and recombinant human interleukin 1β (0.15 ng/ml) resulted in a more pronounced suppression of basal insulin release than with interleukin 1β alone (55 ± 3.6% vs 44 ± 3.6% with interleukin 1β alone, p < 0.05) but did not reduce interleukin 1β-stimulated NO production or reverse the effect of interleukin 1β on cell viability. Thus, in pancreatic islets interleukin 10 is not capable of counteracting the interleukin 1β-induced β-cell dysfunction, but rather enhances the inhibitory effect of interleukin 1β by a different mechanism. Renato Laffranchi, Division of Endocrinology and Metabolism, Department of Internal Medicine, University Hospital, Rämistrasse 100, CH-8091 Zürich, Switzerland

microRNA-203 suppresses invasion of gastric cancer cells by targeting ERK1/2/Slug/ E-cadherin signaling

2017 ◽  
Vol 19 (1) ◽  
pp. 11-20 ◽  
Author(s):  
Peng Gao ◽  
Shijie Wang ◽  
Fuchun Jing ◽  
Jiang Zhan ◽  
Yunhui Wang
Keyword(s):  
Gastric Cancer ◽  
Cancer Cells ◽  
Gastric Cancer Cells ◽  
E Cadherin

Lignans from guaiac resin decrease nitric oxide production in interleukin 1β-treated hepatocytes

2016 ◽  
Vol 71 (1) ◽  
pp. 190-197 ◽  
Author(s):  
Yuki Nakano ◽  
Masaaki Nasu ◽  
Mana Kano ◽  
Hiroshi Kameoka ◽  
Tetsuya Okuyama ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Interleukin 1Β ◽  
Nitric Oxide Production ◽  
Oxide Production
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