Discovery of Novel Muscarinic Receptor Modulators by Integrating a Natural Product Framework and a Bioactive Molecule

ChemMedChem ◽  
2018 ◽  
Vol 13 (4) ◽  
pp. 384-395 ◽  
Author(s):  
Rajesh Varkhedkar ◽  
Shalini Dogra ◽  
Divya Tiwari ◽  
Yusuf Hussain ◽  
Prem Narayan Yadav ◽  
...  
Keyword(s):  
Natural Product ◽  
Muscarinic Receptor ◽  
Bioactive Molecule ◽  
Receptor Modulators

Effects of muscarinic receptor modulators on ocular biometry of guinea pigs

2014 ◽  
Vol 35 (1) ◽  
pp. 60-69 ◽  
Author(s):  
Fang Fang ◽  
Furong Huang ◽  
Ruozhong Xie ◽  
Cheng Li ◽  
Yin Liu ◽  
...  
Keyword(s):  
Muscarinic Receptor ◽  
Guinea Pigs ◽  
Ocular Biometry ◽  
Receptor Modulators

Influence of muscarinic receptor modulators on interacerebroventricular injection of arachydonylcyclopropylamide induced antinociception in mice

2015 ◽  
Vol 138 ◽  
pp. 273-278 ◽  
Author(s):  
Mohammad R. Jafari ◽  
Samaneh Onsori ◽  
Fatemeh Fekrmandi ◽  
Pouria Tabrizian ◽  
Mohsen Alipour ◽  
...  
Keyword(s):  
Muscarinic Receptor ◽  
Receptor Modulators

The Effect of Muscarinic Receptor Modulators on the Antinociception Induced by CB2 Receptor Agonist, JWH133 in Mice

Drug Research ◽  
2016 ◽  
Vol 66 (11) ◽  
pp. 597-602
Author(s):  
M. Alipour ◽  
F. Fekrmandi ◽  
S. Onsori ◽  
P. Tabrizian ◽  
M. Jafari
Keyword(s):  
Muscarinic Receptor ◽  
Receptor Agonist ◽  
Cb2 Receptor ◽  
Receptor Modulators

scholarly journals Quinolizidinone Carboxylic Acids as CNS Penetrant, Selective M1 Allosteric Muscarinic Receptor Modulators

2010 ◽  
Vol 1 (6) ◽  
pp. 263-267 ◽  
Author(s):  
Scott D. Kuduk ◽  
Ronald K. Chang ◽  
Christina N. Di Marco ◽  
William J. Ray ◽  
Lei Ma ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Muscarinic Receptor ◽  
Receptor Modulators

scholarly journals Effect of Muscarinic Receptor Modulators in the Hypothalamic Supraoptic Nucleus of the Rat

1994 ◽  
Vol 66 (4) ◽  
pp. 413-419 ◽  
Author(s):  
Mayumi Mori ◽  
Hiromi Tsushima ◽  
Toshio Kamiya ◽  
Tomohiro Matsuda
Keyword(s):  
Muscarinic Receptor ◽  
Supraoptic Nucleus ◽  
Receptor Modulators ◽  
Hypothalamic Supraoptic Nucleus

Synthetic studies toward inducamide C

2021 ◽  
Author(s):  
Ardalan A. Nabi ◽  
Lydia M. Scott ◽  
Daniel P. Furkert ◽  
Jonathan Sperry
Keyword(s):  
Natural Product ◽  
Structural Revision ◽  
Synthetic Studies

The rare benzoxazepine ring in the alkaloid inducamide C is unstable and prone to rearrangement, indicating that structural revision of the natural product may be necessary.

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