Crystal Structure and Host-Guest Binding Ability of Three Types of Pillar[5]arenes

2015 ◽  
Vol 33 (3) ◽  
pp. 346-350 ◽  
Author(s):  
Luzhi Liu ◽  
Wengui Duan ◽  
Yuhui Kou ◽  
Lingyun Wang ◽  
Herbert Meier ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Binding Ability ◽  
Guest Binding

Dependence of guest-binding ability on cavity shape of deformed cyclodextrins

1996 ◽  
Vol 37 (11) ◽  
pp. 1825-1828 ◽  
Author(s):  
Kahee Fujita ◽  
Yuji Okabe ◽  
Kazuko Ohta ◽  
Hatsuo Yamamura ◽  
Tsutomu Tahara ◽  
...  
Keyword(s):  
Binding Ability ◽  
Cavity Shape ◽  
Guest Binding

Remote Impacts of Methyl Substituents on the Guest-Binding Ability of Self-Assembled Cages

2014 ◽  
Vol 9 (5) ◽  
pp. 1321-1328 ◽  
Author(s):  
Yu Fang ◽  
Takashi Murase ◽  
Makoto Fujita
Keyword(s):  
Binding Ability ◽  
Guest Binding ◽  
Self Assembled

Extremely Promoted Guest Binding Ability of γ-Cyclodextrin Bearing a Pyrene Derivative on the Secondary Hydroxyl Side

1992 ◽  
Vol 21 (10) ◽  
pp. 2005-2008 ◽  
Author(s):  
Iwao Suzuki ◽  
Yoshinobu Sakurai ◽  
Masahiro Ohkubo ◽  
Akihiko Ueno ◽  
Tetsuo Osa
Keyword(s):  
Binding Ability ◽  
Secondary Hydroxyl ◽  
Guest Binding

Conformational Studies of Triazole Based Flexible Molecules: A Comparative Analysis of Crystal Structure and Optimized Structure for DNA Binding Ability

2017 ◽  
Vol 2 (12) ◽  
pp. 3444-3451
Author(s):  
Ranjeet Kumar ◽  
Pratima Yadav ◽  
Shiv Pal ◽  
Krishnan R. Kumar ◽  
Balasubramanian Sridhar ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Comparative Analysis ◽  
Dna Binding ◽  
Binding Ability ◽  
Conformational Studies ◽  
Flexible Molecules

Synthesis of peptide dendrimers based on a β-cyclodextrin core with guest binding ability

2003 ◽  
Vol 44 (32) ◽  
pp. 6125-6128 ◽  
Author(s):  
Abdullah M.A. Muhanna ◽  
Emilia Ortiz-Salmerón ◽  
Luis Garcı́a-Fuentes ◽  
Juan J. Giménez-Martı́nez ◽  
Antonio Vargas-Berenguel
Keyword(s):  
Binding Ability ◽  
Peptide Dendrimers ◽  
Guest Binding

Crystal structure, DNA-binding ability and cytotoxic activity of platinum(II) 2,2′-dipyridylamine complexes

2004 ◽  
Vol 357 (1) ◽  
pp. 95-102 ◽  
Author(s):  
Chao Tu ◽  
Xuefeng Wu ◽  
Qin Liu ◽  
Xiaoyong Wang ◽  
Qiang Xu ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Dna Binding ◽  
Cytotoxic Activity ◽  
Binding Ability

scholarly journals Novel Structure and Unexpected RNA-Binding Ability of the C-Terminal Domain of Herpes Simplex Virus 1 Tegument Protein UL21

2016 ◽  
Vol 90 (12) ◽  
pp. 5759-5769 ◽  
Author(s):  
Claire M. Metrick ◽  
Ekaterina E. Heldwein
Keyword(s):  
Crystal Structure ◽  
Herpes Simplex ◽  
Rna Binding ◽  
Tegument Protein ◽  
Functional Importance ◽  
Binding Ability ◽  
Herpes Simplex Virus 1 ◽  
3 Dimensional ◽  
Terminal Domain ◽  
Simplex Virus

ABSTRACTProteins forming the tegument layers of herpesviral virions mediate many essential processes in the viral replication cycle, yet few have been characterized in detail. UL21 is one such multifunctional tegument protein and is conserved among alphaherpesviruses. While UL21 has been implicated in many processes in viral replication, ranging from nuclear egress to virion morphogenesis to cell-cell spread, its precise roles remain unclear. Here we report the 2.7-Å crystal structure of the C-terminal domain of herpes simplex virus 1 (HSV-1) UL21 (UL21C), which has a unique α-helical fold resembling a dragonfly. Analysis of evolutionary conservation patterns and surface electrostatics pinpointed four regions of potential functional importance on the surface of UL21C to be pursued by mutagenesis. In combination with the previously determined structure of the N-terminal domain of UL21, the structure of UL21C provides a 3-dimensional framework for targeted exploration of the multiple roles of UL21 in the replication and pathogenesis of alphaherpesviruses. Additionally, we describe an unanticipated ability of UL21 to bind RNA, which may hint at a yet unexplored function.IMPORTANCEDue to the limited genomic coding capacity of viruses, viral proteins are often multifunctional, which makes them attractive antiviral targets. Such multifunctionality, however, complicates their study, which often involves constructing and characterizing null mutant viruses. Systematic exploration of these multifunctional proteins requires detailed road maps in the form of 3-dimensional structures. In this work, we determined the crystal structure of the C-terminal domain of UL21, a multifunctional tegument protein that is conserved among alphaherpesviruses. Structural analysis pinpointed surface areas of potential functional importance that provide a starting point for mutagenesis. In addition, the unexpected RNA-binding ability of UL21 may expand its functional repertoire. The structure of UL21C and the observation of its RNA-binding ability are the latest additions to the navigational chart that can guide the exploration of the multiple functions of UL21.

Synthesis, characterization, crystal structure, DNA/BSA binding ability and antibacterial activity of asymmetric europium complex based on 1,10- phenanthroline

2017 ◽  
Vol 1137 ◽  
pp. 771-783 ◽  
Author(s):  
Nafiseh Alfi ◽  
Mozhgan Khorasani-Motlagh ◽  
Ali Reza Rezvani ◽  
Meissam Noroozifar ◽  
Krešimir Molčanov
Keyword(s):  
Crystal Structure ◽  
Antibacterial Activity ◽  
Europium Complex ◽  
Binding Ability ◽  
Bsa Binding
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