Interaction between (1,1′-Binaphthalene)-2,2′-diol and Lecithin Liposome

2010 ◽  
Vol 28 (2) ◽  
pp. 193-198 ◽  
Author(s):  
Liuhua Chen ◽  
Lihua Gan ◽  
Shenjing An ◽  
Dazhang Zhu ◽  
Zijie Xu ◽  
...  
Keyword(s):  
Lecithin Liposome

Calcium Fortification of Soy Milk with Calcium-Lecithin Liposome System

1984 ◽  
Vol 49 (4) ◽  
pp. 1111-1112 ◽  
Author(s):  
MOTOHIKO HIROTSUKA ◽  
HITOSHI TANIGUCHI ◽  
HIROSHI NARITA ◽  
MAKOTO KITO
Keyword(s):  
Soy Milk ◽  
Liposome System ◽  
Lecithin Liposome

Protective Effect of Amphiphilic Ammonium Salts on the Oxidation of Lecithin Liposomes

1995 ◽  
Vol 50 (11-12) ◽  
pp. 840-844
Author(s):  
J Gabrielska ◽  
H Kleszczyriska ◽  
S Przestalski
Keyword(s):  
Chain Length ◽  
Alkyl Chain ◽  
Uv Light ◽  
Alkyl Chain Length ◽  
Ammonium Salts ◽  
Ferrous Ions ◽  
Liposome Membrane ◽  
Similar Dependence ◽  
Substituted Ammonium Salts ◽  
Lecithin Liposome

Abstract The inhibition effect of selected amphiphilic quaternary alkyl-substituted ammonium salts on oxidation of the lecithin liposome membrane was studied, induced by ultraviolet light and Fe2+ ions with ascorbic acid added. The salts differed in alkyl chain length Ri having the following alkyl substitutents: R1 = C9H19; R2 = C10H21; R3 = C12H25; R4 = CH2OC14H29; R5 = CH2OC16H33. It was found that all the salts used induced inhibition in oxidation of the liposome membrane, both that induced by UV light and ferrous ions. The antioxidant activity of the salts studied, dependent on the chain length and concentration, can be represented by the relation R1 < R2< R3 < R4 < R5. A similar dependence was obtained when the hemolytic activity of compounds was studied. Activity of salts increase with alkyl chain length.

Lipid microspheres incorporated by U937 cells via their specific receptors

2001 ◽  
Vol 79 (2) ◽  
pp. 177-182
Author(s):  
Kimihiro Suzuki ◽  
Toshihiko Hidaka ◽  
Tadashi Shinohara ◽  
Kouji Kataharada ◽  
Makoto Okada ◽  
...  
Keyword(s):  
Membrane Fraction ◽  
Lipid Emulsion ◽  
Drug Carriers ◽  
U937 Cells ◽  
Serum Free Medium ◽  
Free Medium ◽  
Serum Free ◽  
Specific Receptors ◽  
Single Binding Site ◽  
Lecithin Liposome

Lipid microspheres (LM), currently in clinical use as drug carriers, mainly consist of soybean oil as a core and lecithin as a surfactant. The purpose of our study wass to determine whether or not LM incorporation is receptor-mediated. U937 cells resuspended in a serum-free medium abundantly took up unmodulated LM. A binding study showed that U937 cells had a single binding site for LM (410 sites/cell at 24°C; 100 sites/cell at 4°C). Inhibition assays revealed that lecithin liposome, lysophosphatidylcholines, activated α2-macroglobulin, and HDL did not affect the binding of LM to U937 cells. VLDL strongly, and LDL and AcLDL moderately, inhibited the binding of LM to U937 cells. Ligand blotting analysis revealed that unmodulated LM in an apoprotein-free buffer directly bound to a 40 kDa protein in the cell membrane fraction. These results suggest that LM that is not modulated by any protein is incorporated by specific cells via receptor-mediated processes.Key words: lipid emulsion, drug delivery system, monocyte, free fatty acids.

Organometallics and Quaternary Ammonium Salts Affect Calcium Ion Desorption from Lecithin Liposome Membranes

2001 ◽  
Vol 56 (5-6) ◽  
pp. 395-401
Author(s):  
Teresa E. Krai ◽  
Janina Kuczera ◽  
Stanisław Przestalski
Keyword(s):  
Heavy Metals ◽  
Quaternary Ammonium ◽  
Calcium Ion ◽  
Organometallic Compounds ◽  
Quaternary Ammonium Salts ◽  
Biologically Active ◽  
Ammonium Salts ◽  
Ion Desorption ◽  
Synergism And Antagonism ◽  
Lecithin Liposome

The objective of the present work was to compare the effects of groups of tin and lead organometallic compounds and their mixtures with amphiphilic quaternary ammonium salts (QAS) on the process of calcium ion desorption from lecithin liposome membranes, as dependent on the properties of the hydrophilic and hydrophobic parts of QAS. In the investigations the method of radioactive labels was applied. Synergism and antagonism in the action of both groups of compounds were found. The effectiveness of the cooperation depended more on chain length of QAS compounds than on the size and polarity of their hydrophobic parts. The most effective of all compounds studied was a the mixture of benzyldimethylammonium chloride in a mixture with tripropyltin. Since the rate of calcium desorption proved to be a good measure of efficacy of biologically active surfactants, it seems that the conclusions reached in this paper may be useful for choosing compounds which are able to decontaminate the environment polluted with heavy metals.

Antioxidant activity of grape extracts in a lecithin liposome system

1997 ◽  
Vol 74 (10) ◽  
pp. 1301-1307 ◽  
Author(s):  
Ock-Sook Yi ◽  
Anne S. Meyer ◽  
Edwin N. Frankel
Keyword(s):  
Antioxidant Activity ◽  
Liposome System ◽  
Lecithin Liposome

The inducing effect of lecithin liposome organic template on the nucleation and crystal growth of calcium carbonate

2009 ◽  
Vol 29 (1) ◽  
pp. 222-227 ◽  
Author(s):  
Peng Wan ◽  
Yu Zhao ◽  
Hua Tong ◽  
Ziying Yang ◽  
Zhihong Zhu ◽  
...  
Keyword(s):  
Crystal Growth ◽  
Calcium Carbonate ◽  
Organic Template ◽  
Lecithin Liposome
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