Characterization and optimization of hydrothermal extraction of quercetin from Quercus leaves using response surface methodology

2021 ◽  
Author(s):  
Haoling Shen ◽  
Jiaojiao Zhang ◽  
Chensi Guo ◽  
Xiangyu Gao ◽  
Junying Chen ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Hydrothermal Extraction

scholarly journals Optimization of Extraction Conditions for Antioxidant Activity of Acer tegmentosum Using Response Surface Methodology

2021 ◽  
Vol 11 (3) ◽  
pp. 1134
Author(s):  
Inyong Kim ◽  
Jung-Heun Ha ◽  
Yoonhwa Jeong
Keyword(s):  
Hydrogen Peroxide ◽  
Response Surface Methodology ◽  
Response Surface ◽  
Hepg2 Cells ◽  
Extraction Methods ◽  
Total Phenolic ◽  
Extraction Temperature ◽  
Freeze Dried ◽  
Hydrothermal Extraction

Extraction from edible plants is a highly important process that has various biological functions. To maximize biological activity, extraction methods should facilitate optimal extraction of functional phytochemicals. In this study, the optimal hydrothermal extraction conditions of Acer tegmentosum were determined using response surface methodology (RSM), and HepG2 cells were treated with optimized extract and hydrogen peroxide. In a central composition design, the independent variables were extraction temperature (X1: 70–90 °C), extraction time (X2: 2–6 h), and solvent-to-solid ratio (X3: 50–150). The maximum total phenolic contents (276.70 ± 10.11 mg GAE/g) and DPPH (2,2-diphenyl-1-pictylhydrazyl) activity (33.45 ± 2.20%) of A. tegmentosum were estimated at optimized extraction conditions, as follows: X1: 89.34 °C, X2: 7.36 h, X3: 184.09. Using the calculated extraction conditions, functional phytochemicals were extracted by hydrothermal extraction and freeze-dried. A. tegmentosum treatment (>10 μg/mL) of HepG2 cells remarkably attenuated hydrogen-peroxide-inducible hepatic cellular death and reactive oxygen species production in vitro.

Adsorption of Cu(II) Ions on Areca Catechu Stem-Based Activated Carbon: Optimization Using Response Surface Methodology

2019 ◽  
Vol 12 (2) ◽  
pp. 123
Author(s):  
Abrar Muslim ◽  
Marwan Marwan ◽  
Ramli Saifullah ◽  
Muhammad Yahya Azwar ◽  
Darmadi Darmadi ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Activated Carbon ◽  
Response Surface ◽  
Areca Catechu
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