Circular Dichroism Studies on Intermolecular Interactions of Amphotericin B in Ionic Liquid-Rich Environments

Chirality ◽  
2013 ◽  
Vol 25 (7) ◽  
pp. 427-432 ◽  
Author(s):  
Laramie P. Jameson ◽  
Sergei V. Dzyuba
Keyword(s):  
Ionic Liquid ◽  
Circular Dichroism ◽  
Amphotericin B ◽  
Intermolecular Interactions ◽  
Circular Dichroïsm

scholarly journals Effect of imidazolium room-temperature ionic liquids on aggregation of amphotericin B: a circular dichroism study

RSC Advances ◽  
2015 ◽  
Vol 5 (98) ◽  
pp. 80325-80329 ◽  
Author(s):  
Laramie P. Jameson ◽  
Sergei V. Dzyuba
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Circular Dichroism ◽  
Amphotericin B ◽  
Room Temperature ◽  
Room Temperature Ionic Liquid ◽  
Room Temperature Ionic Liquids ◽  
Circular Dichroïsm

The aggregate–monomer equilibrium of amphotericin B could be controlled by the structure of the room-temperature ionic liquid.

Glucose in dry and moist ionic liquid: vibrational circular dichroism, IR, and possible mechanisms

2020 ◽  
Vol 22 (19) ◽  
pp. 10726-10737 ◽  
Author(s):  
Jan Blasius ◽  
Roman Elfgen ◽  
Oldamur Hollóczki ◽  
Barbara Kirchner
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Circular Dichroism ◽  
Molecular Level ◽  
Vibrational Circular Dichroism ◽  
Circular Dichroïsm

The molecular level specification of glucose monomers in ionic liquids and their mixtures with water helps understanding cellulose processing in these liquids.

Intermolecular Interactions of Polypeptides and Lipids in the Thylakoid Membrane

1976 ◽  
Vol 31 (7-8) ◽  
pp. 436-444 ◽  
Author(s):  
Wilhelm Menke ◽  
Alfons Radunz ◽  
Georg H. Schmid ◽  
Koenig Friederike ◽  
Rolf-Dieter Hirtz
Keyword(s):  
Circular Dichroism ◽  
Intermolecular Interactions ◽  
Ph Dependence ◽  
Covalent Binding ◽  
Average Molecular Weight ◽  
Sodium Dodecyl ◽  
Light Reaction ◽  
Dodecyl Sulfate ◽  
Ph Range ◽  
Circular Dichroïsm

Abstract Intermolecular interactions between chloroplast lipids and a polypeptide fraction from thylakoids were investigated by far ultraviolet circular dichroism. The polypeptide fraction was isolated from dodecyl sulfate-containing buffers. It exhibits an average molecular weight of 24 000. The circular dichroism of this polypeptide fraction measured as mean residue ellipticity is greater in the presence of sodium dodecyl sulfate than in the absence of this detergent. This effect is reversible. Addition of sulfoquinovosyl diglyceride to the dodecyl sulfate-free solution of the polypeptide also causes an increase of the circular dichroism. This increase was only observed in the pH-range between 6.9 and 7.4. The effect of dodecyl sulfate or sulfolipid on the circular dichroism is interpreted to indicate an increase of α-helix content. Monogalactosyl diglyceride, digalactosyl di­glyceride and phosphatidyl glycerol gave no reaction. The attempt to obtain a conformational analysis of the polypeptide in the different states did not yield an entirely satisfactory result. Antisera to sulfolipid inhibit photosynthetic electron transport of stroma-freed chloroplasts in the region of light reaction I. This inhibition is restricted to the same pH-range as the non-covalent binding of sulfolipid to the polypeptides. It appears that in the cell membrane-bound metabolic processes are regulated by this pH-dependence of the sulfolipid-polypetide interactions.

On the existence of an amphotericin B – sterol complex in lipid vesicles and in propanol–water systems

1987 ◽  
Vol 65 (3) ◽  
pp. 234-238 ◽  
Author(s):  
Ilona Gruda ◽  
Jacques Bolard
Keyword(s):  
Circular Dichroism ◽  
Amphotericin B ◽  
Lipid Bilayer ◽  
Binary Mixtures ◽  
Lipid Vesicles ◽  
Water Systems ◽  
Phospholipid Vesicles ◽  
Positive Cooperativity ◽  
Circular Dichroïsm

The amphotericin B (AmB) – ergosterol complex, formed by interaction of the antibiotic with ergosterol-containing phospholipid vesicles, is associated with the lipid bilayer. It has been shown by circular dichroism studies that the AmB–ergosterol complex formed in water–propanol binary mixtures has a similar structure to that observed in phospholipid vesicles. A positive cooperativity is found for the interaction of AmB with ergosterol. The similar AmB–cholesterol complex is much less stable and rearranges rapidly to a different conformation.

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