Determination of enantiomeric excess for 2,3-dihydroxy-3-phenylpropionate compounds by capillary electrophoresis using hydroxypropyl-β-cyclodextrin as chiral selector

Chirality ◽  
2007 ◽  
Vol 19 (5) ◽  
pp. 380-385 ◽  
Author(s):  
Yan Zhao ◽  
Xing-Bin Yang ◽  
Qiao-Feng Wang ◽  
Peng-Juan Nan ◽  
Ying Jin ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Enantiomeric Excess ◽  
Chiral Selector

scholarly journals Enantioseparation and Determination of Mephedrone and Its Metabolites by Capillary Electrophoresis Using Cyclodextrins as Chiral Selectors

Molecules ◽  
2020 ◽  
Vol 25 (12) ◽  
pp. 2879
Author(s):  
Pavel Řezanka ◽  
Denisa Macková ◽  
Radek Jurok ◽  
Michal Himl ◽  
Martin Kuchař
Keyword(s):  
Capillary Electrophoresis ◽  
Chiral Separation ◽  
Simplex Method ◽  
Background Electrolyte ◽  
Detection Limits ◽  
Chiral Selector ◽  
Designer Drug ◽  
Optimal Composition ◽  
Linear Calibration

Mephedrone, a psychoactive compound derived from cathinone, is widely used as a designer drug. The determination of mephedrone and its metabolites is important for understanding its possible use in medicine. In this work, a method of capillary electrophoresis for the chiral separation of mephedrone and its metabolites was developed. Carboxymethylated β-cyclodextrin was selected as the most effective chiral selector from seven tested cyclodextrin derivates. Based on the simplex method, the optimal composition of the background electrolyte was determined: at pH 2.75 and 7.5 mmol·L−1 carboxymethylated β-cyclodextrin the highest total resolution of a mixture of analytes was achieved. For mephedrone and its metabolites, calibration curves were constructed in a calibration range from 0.2 to 5 mmol·L−1; limits of detection, limits of quantification, precision, and repeatability were calculated, and according to Mandel’s fitting test, the linear calibration ranges were determined.

Separation and determination of ephedrine enantiomers by capillary electrophoresis usingl-leucine as chiral selector

2002 ◽  
Vol 56 (9-10) ◽  
pp. 637-639 ◽  
Author(s):  
Nengsheng Ye ◽  
Xuexin Gu ◽  
Hong Zou ◽  
Ruohua Zhu
Keyword(s):  
Capillary Electrophoresis ◽  
Chiral Selector

Determination of terbutaline enantiomers in human urine by capillary electrophoresis using hydroxypropyl-β-cyclodextrin as a chiral selector

2003 ◽  
Vol 26 (2) ◽  
pp. 120-123 ◽  
Author(s):  
Kim Kyeong Ho ◽  
Seo Sang Hun ◽  
Kim Hyun Ju ◽  
Jeun Eun Young ◽  
Kang Jong-Seong ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Human Urine ◽  
Chiral Selector

An approach to the determination of the enantiomeric excess at the extreme case by capillary electrophoresis

2015 ◽  
Vol 1408 ◽  
pp. 250-254 ◽  
Author(s):  
Hongting Xiao ◽  
Xia Fu ◽  
Shuang Liang ◽  
Youxin Li ◽  
James J. Bao ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Enantiomeric Excess ◽  
Extreme Case

Determination of Enantiomeric Excess of Aromatic 1,2-Diols with HP-β-Cyclodextrin as Chiral Selector by CE

2007 ◽  
Vol 66 (7-8) ◽  
pp. 601-605 ◽  
Author(s):  
Y. Zhao ◽  
X. B. Yang ◽  
Q. F. Wang ◽  
X. L. Sun ◽  
R. Jiang ◽  
...  
Keyword(s):  
Enantiomeric Excess ◽  
Chiral Selector
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