ChemInform Abstract: Carbamoyl Anion-Initiated Cascade Reaction for Stereoselective Synthesis of Substituted α-Hydroxy-β-Amino Amides.

ChemInform ◽  
2016 ◽  
Vol 47 (20) ◽  
Author(s):  
Chao-Yang Lin ◽  
Peng-Ju Ma ◽  
Zhao Sun ◽  
Chong-Dao Lu ◽  
Yan-Jun Xu
2016 ◽  
Vol 52 (5) ◽  
pp. 912-915 ◽  
Author(s):  
Chao-Yang Lin ◽  
Peng-Ju Ma ◽  
Zhao Sun ◽  
Chong-Dao Lu ◽  
Yan-Jun Xu

A carbamoyl anion-initiated cascade reaction with acylsilanes and imines allows rapid construction of substituted α-hydroxy-β-amino amides in high yields with excellent diastereoselectivities.


2020 ◽  
Vol 2020 (11) ◽  
pp. 1700-1707
Author(s):  
Akio Kamimura ◽  
Tomoyuki Itaya ◽  
Tatsuro Yoshinaga ◽  
Ryo Nozawa ◽  
Takuji Kawamoto ◽  
...  

2018 ◽  
Vol 20 (23) ◽  
pp. 7585-7589 ◽  
Author(s):  
Nicholas P. Massaro ◽  
Joseph C. Stevens ◽  
Aayushi Chatterji ◽  
Indrajeet Sharma

2019 ◽  
Vol 9 (15) ◽  
pp. 4083-4090 ◽  
Author(s):  
Ángela Mourelle-Insua ◽  
Daniel Méndez-Sánchez ◽  
James L. Galman ◽  
Iustina Slabu ◽  
Nicholas J. Turner ◽  
...  

A transaminase-catalyzed dynamic kinetic resolution is described for the stereoselective synthesis of a series of α-alkyl-β-amino amides.


Author(s):  
Shuai-Jiang Liu ◽  
Qing Mao ◽  
Gu Zhan ◽  
Rui Qin ◽  
Ben-Hong Chen ◽  
...  

A series of newly prepared 3-((2,2,2-trifluoroethyl)amino)indolin-2-ones for the facile synthesis of chiral 3,2′-spirooxindole γ-lactam products containing trifluoroethyl groups have been developed.


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