ChemInform Abstract: Synthetic Mononuclear Nonheme Iron-Oxygen Intermediates

ChemInform ◽  
2015 ◽  
Vol 46 (43) ◽  
pp. no-no
Author(s):  
Wonwoo Nam
Keyword(s):  
Nonheme Iron ◽  
Oxygen Intermediates

Dioxygen Activation by Mononuclear Nonheme Iron(II) Complexes Generates Iron−Oxygen Intermediates in the Presence of an NADH Analogue and Proton

2009 ◽  
Vol 131 (39) ◽  
pp. 13910-13911 ◽  
Author(s):  
Seungwoo Hong ◽  
Yong-Min Lee ◽  
Woonsup Shin ◽  
Shunichi Fukuzumi ◽  
Wonwoo Nam
Keyword(s):  
Nonheme Iron ◽  
Dioxygen Activation ◽  
Oxygen Intermediates

KIDNEY INJURY IN CANCER THERAPY

2018 ◽  
Vol 22 (5) ◽  
pp. 17-24 ◽  
Author(s):  
E. V. Burnasheva ◽  
Y. V. Shatokhin ◽  
I. V. Snezhko ◽  
A. A. Matsuga
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Cancer Therapy ◽  
Cancer Patients ◽  
Cytotoxic Effect ◽  
Tumor Lysis Syndrome ◽  
Kidney Injury ◽  
Chemotherapeutic Agents ◽  
Oxygen Intermediates ◽  
Circulating Blood Volume

Кidney injury is a frequent and significant complication of cancer and cancer therapy. The kidneys are susceptible to injury from malignant infiltration, damage by metabolites of malignant cells, glomerular  injury, nephrotoxic drugs including chemotherapeutic agents. Also  bone marrow transplantation complications, infections with immune  suppression (including septicemia), tumor lysis syndrome should be  taken into account. Chemotherapeutic agents are a common cause  of acute kidney injury but can potentially lead to chronic kidney  disease development in cancer patients. This article summarizes risk  factors of acute kidney injury in cancer patients. Risk factors are  divided into two groups. The systemic are decrease of total  circulating blood volume, infiltration of kidney tissue by tumor cells,  dysproteinemia, electrolyte disturbances. The local (renal) risk  factors are microcirculation disturbances, drugs biotransformation  with formation of reactive oxygen intermediates, high concentration of nephrotoxic agents in proximal tubules and its  sensitivity to ischemia. Drug-related risk factors include: drugs  combination with cytotoxic effect high doses long term use necessity, direct cytotoxic effect of not only chemotherapeutic agents but also its metabolites, mean solubility forming intratubular  precipitates. Early diagnosis, timely prevention and treatment of  these complications provide significantly improve nononcologic results of treatment.

Spectroscopic capture and reactivity of S = 1/2 nickel(iii)–oxygen intermediates in the reaction of a NiII-salt with mCPBA

2012 ◽  
Vol 48 (31) ◽  
pp. 3730 ◽  
Author(s):  
Florian Felix Pfaff ◽  
Florian Heims ◽  
Subrata Kundu ◽  
Stefan Mebs ◽  
Kallol Ray
Keyword(s):  
Oxygen Intermediates

pH Changes That Induce an Axial Ligand Effect on Nonheme Iron(IV) Oxo Complexes with an Appended Aminopropyl Functionality

2021 ◽  
Author(s):  
Reza Latifi ◽  
Taryn D. Palluccio ◽  
Wanhua Ye ◽  
Jennifer L. Minnick ◽  
Kwame S. Glinton ◽  
...  
Keyword(s):  
Axial Ligand ◽  
Nonheme Iron ◽  
Ligand Effect ◽  
Ph Changes ◽  
Oxo Complexes

scholarly journals Obesity-Related Hypoferremia Is Not Explained by Differences in Reported Intake of Heme and Nonheme Iron or Intake of Dietary Factors that Can Affect Iron Absorption

2008 ◽  
Vol 108 (1) ◽  
pp. 145-148 ◽  
Author(s):  
Carolyn M. Menzie ◽  
Lisa B. Yanoff ◽  
Blakeley I. Denkinger ◽  
Teresa McHugh ◽  
Nancy G. Sebring ◽  
...  
Keyword(s):  
Iron Absorption ◽  
Nonheme Iron ◽  
Dietary Factors
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