Abstract:
β-Amino-α,β-enones or β-enamino carbonyl compounds are versatile synthons intermediates for the construction of various bio-active heterocyclic compounds and have been established as multipurpose synthetic precursors in organic syntheses and in pharmaceutical developments. In this work, we will discuss the different synthetic routes to obtain β-Amino-α,β-enones or β-enamino carbonyl compounds, their reactions, and their utility in the construction of organic frameworks and heterocyclic ring systems. Structurally, β-amino-α,β-enones are attractive intermediates that syndicate the ambident behaviours of nucleophilicity and electrophilicity of enones simultaneously. β-amino-α,β-enones have been known as acceptors in both 1,2- and 1,4- additions, which make them good intermediate compounds for annulation to different heterocycles.
Recent advances in carbon nanospheres: synthetic routes and applications