ChemInform Abstract: Synthetic Studies on Natural Products. Part 74. Stereoselective Total Synthesis of psiAβ - A Sporogenic Psi Factor from Aspergillus nidulans.

ChemInform ◽  
2014 ◽  
Vol 45 (46) ◽  
pp. no-no
Author(s):  
Parigi Raghavendar Reddy ◽  
Maram Lingaiah ◽  
Biswanath Das
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Aspergillus Nidulans ◽  
Synthetic Studies

scholarly journals Total synthesis and structural elucidation of natural products: (–)-Delactonmycin, (+)-plumerinine, and (–)-parvistemoamide

2005 ◽  
Vol 77 (7) ◽  
pp. 1153-1160 ◽  
Author(s):  
Ronaldo A. Pilli ◽  
Ivan R. Corrêa ◽  
Adriano O. Maldaner ◽  
Giovanni B. Rosso
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Inhibitory Activity ◽  
Structural Elucidation ◽  
Relative Configuration ◽  
Synthetic Studies ◽  
Hiv 1 ◽  
Rev Protein

Synthetic studies that established the relative configuration of (–)-delactonmycin, a polyketide with inhibitory activity against HIV-1 Rev protein, and our efforts toward the structural elucidation of the alkaloids (+)-plumerinine, isolated from P. rubra, and (–)-parvistemoamide, isolated from S. parviflora, are discussed.

Synthetic Studies in the Veratrum Alkaloid Series. II. The Total Synthesis of Verarine, Veratramine, Jervine, and Veratrobasine

1975 ◽  
Vol 53 (12) ◽  
pp. 1796-1817 ◽  
Author(s):  
James P. Kutney ◽  
John Cable ◽  
William A. F. Gladstone ◽  
Harald W. Hanssen ◽  
G. Vijay Nair ◽  
...  
Keyword(s):  
Natural Products ◽  
Double Bond ◽  
Total Synthesis ◽  
Similar Sequence ◽  
Synthetic Studies ◽  
Subsequent Introduction ◽  
Methyl Pyridine

Coupling of 3β-acetoxy-5α-etiojerv-12(13)-en-17-one (1) with the lithio derivative of 2-ethyl-5-methylpyridine provides the crucial intermediate (3) for the subsequent elaboration to verarine. Aromatization of 3 to 4 and reduction of the latter provides a mixture from which N-acetyl-5α,6-dihydroverarine (11) was isolated. Subsequent introduction of the 5,6-double bond in the latter and removal of the N-acetate function completed the synthesis of verarine (31). In a similar sequence of reactions employing 1 and the lithio derivative of 2-ethyl-3-methoxy-5-methyl-pyridine, the resultant intermediate (54), was elaborated to 5α,6-dihydroveratramine (56). Due to known conversions of the latter to veratramine (14), jervine (32), veratrobasine (33), and 11-deoxojervine (34), the formal total synthesis of these natural products is complete.

Isolation, biological activity, biosynthesis and synthetic studies towards the rubromycin family of natural products

2015 ◽  
Vol 32 (6) ◽  
pp. 811-840 ◽  
Author(s):  
Darcy J. Atkinson ◽  
Margaret A. Brimble
Keyword(s):  
Natural Products ◽  
Biological Activity ◽  
Total Synthesis ◽  
Synthetic Studies

The rubromycins are a unique family of natural products. This review covers their isolation, biological activity, biosynthesis and a detailed discussion of the diverse chemistry employed for total synthesis.

ChemInform Abstract: Synthetic Studies on Natural Products. Part 39. Total Synthesis of Racemic and (R)- and (S)-4-Methoxyalkanoic Acids and Their Antifungal Activity.

ChemInform ◽  
2011 ◽  
Vol 42 (41) ◽  
pp. no-no
Author(s):  
Biswanath Das ◽  
Digambar Balaji Shinde ◽  
Boddu Shashi Kanth ◽  
Avijeet Kamle ◽  
C. Ganesh Kumar
Keyword(s):  
Natural Products ◽  
Antifungal Activity ◽  
Total Synthesis ◽  
Synthetic Studies

scholarly journals Recent Chemical Methodology Advances in the Total Synthesis of Meroterpenoids

2021 ◽  
Vol 68 (2) ◽  
pp. 247-267
Author(s):  
Jan Petrovčič ◽  
Chad Nicholas Ungarean ◽  
David Sarlah
Keyword(s):  
Organic Chemistry ◽  
Natural Products ◽  
Total Synthesis ◽  
Feature Article ◽  
Total Syntheses ◽  
Synthetic Organic Chemistry ◽  
Synthetic Studies

Heterogeneity of meroterpenoids arising from their dual biosynthetic origins is constantly provoking synthetic chemists to utilize their ingenuity and revise their retrosynthetic logic. By studying recent publications on meroterpenoid synthesis,tremendous advances in the field of synthetic organic chemistry can be witnessed. This feature article covers some of the most intriguing total syntheses and synthetic studies towards the meroterpenoid class of natural products from the last five years.

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