ChemInform Abstract: A New Strategy for Facile Synthesis of Tetrasubstituted Pyridine Derivatives.

ChemInform ◽  
2013 ◽  
Vol 45 (2) ◽  
pp. no-no
Author(s):  
Jun Chen ◽  
Hangcheng Ni ◽  
Wenteng Chen ◽  
Guolin Zhang ◽  
Yongping Yu
Keyword(s):  
Pyridine Derivatives ◽  
Facile Synthesis ◽  
New Strategy

A new strategy for facile synthesis of tetrasubstituted pyridine derivatives

Tetrahedron ◽  
2013 ◽  
Vol 69 (37) ◽  
pp. 8069-8073 ◽  
Author(s):  
Jun Chen ◽  
Hangcheng Ni ◽  
Wenteng Chen ◽  
Guolin Zhang ◽  
Yongping Yu
Keyword(s):  
Pyridine Derivatives ◽  
Facile Synthesis ◽  
New Strategy

A FACILE SYNTHESIS AND REACTIONS OF AMINO SELENOLO[2,3-b]PYRIDINE CARBOXYLATE

2015 ◽  
Vol 12 (1) ◽  
pp. 3910-3918 ◽  
Author(s):  
Dr Remon M Zaki ◽  
Prof Adel M. Kamal El-Dean ◽  
Dr Nermin A Marzouk ◽  
Prof Jehan A Micky ◽  
Mrs Rasha H Ahmed
Keyword(s):  
Biological Activity ◽  
Carbonyl Compounds ◽  
Mass Spectra ◽  
The Other ◽  
Pyridine Derivatives ◽  
Facile Synthesis ◽  
High Biological Activity ◽  
Basic Hydrolysis ◽  
Pyridine Carboxylate ◽  
Hydrolysis Of

 Incorporating selenium metal bonded to the pyridine nucleus was achieved by the reaction of selenium metal with 2-chloropyridine carbonitrile 1 in the presence of sodium borohydride as reducing agent. The resulting non isolated selanyl sodium salt was subjected to react with various α-halogenated carbonyl compounds to afford the selenyl pyridine derivatives 3a-f  which compounds 3a-d underwent Thorpe-Ziegler cyclization to give 1-amino-2-substitutedselenolo[2,3-b]pyridine compounds 4a-d, while the other compounds 3e,f failed to be cyclized. Basic hydrolysis of amino selenolo[2,3-b]pyridine carboxylate 4a followed by decarboxylation furnished the corresponding amino selenolopyridine compound 6 which was used as a versatile precursor for synthesis of other heterocyclic compound 7-16. All the newly synthesized compounds were established by elemental and spectral analysis (IR, 1H NMR) in addition to mass spectra for some of them hoping these compounds afforded high biological activity.

Synthetic Studies Using α,β-Unsaturated Nitriles: Facile Synthesis of Pyridine Derivatives

Synthesis ◽  
1981 ◽  
Vol 1981 (07) ◽  
pp. 531-533 ◽  
Author(s):  
Satoshi Kambe ◽  
Koji Saito ◽  
Akio Sakurai ◽  
Hiroshi Midorikawa
Keyword(s):  
Pyridine Derivatives ◽  
Facile Synthesis ◽  
Synthetic Studies

A facile synthesis of new 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxamido-3-carboxythieno[2,3-c]pyridine derivatives as potential endothelin receptors ligands

Il Farmaco ◽  
2005 ◽  
Vol 60 (9) ◽  
pp. 711-720 ◽  
Author(s):  
Valeria Pittalà ◽  
Maria Modica ◽  
Giuseppe Romeo ◽  
Luisa Materia ◽  
Loredana Salerno ◽  
...  
Keyword(s):  
Endothelin Receptors ◽  
Pyridine Derivatives ◽  
Facile Synthesis

scholarly journals Efficient and Facile Synthesis of Chromenopyrano[2,3-b] pyridine Derivatives Catalyzed by Sodium Carbonate

2021 ◽  
Vol 68 (2) ◽  
pp. 332-340
Author(s):  
Raziyeh Keshavarz ◽  
Mahnaz Farahi ◽  
Bahador Karami
Keyword(s):  
Sodium Carbonate ◽  
Aromatic Aldehydes ◽  
Dimethyl Acetylenedicarboxylate ◽  
Pyridine Derivatives ◽  
Facile Synthesis ◽  
Bioactive Heterocycles ◽  
High Yields ◽  
Silica Sodium Carbonate

In this research, a number of new and known chromenopyrano[2,3-b]pyridine derivatives have been prepared. Initially, according to the reported procedure, pyrano[2,3-c]chromene derivatives were synthesized by the reaction between 4-hydroxycoumarin, aromatic aldehydes and malononitrile using silica sodium carbonate (SSC) as the catalyst. Next, the prepared pyrano[2,3-c]chromenes were reacted by dimethyl acetylenedicarboxylate (DMAD) or cyclohexanone in the presence of sodium carbonate to produce chromenopyrano[2,3-b]pyridine derivatives. The presented protocol avoids the use of expensive catalysts and gives useful potentially bioactive heterocycles in excellent to high yields.

scholarly journals Facile synthesis and exploration of excited state assisted two-photon absorption properties of D–A–D type thiophene–pyridine derivatives

2020 ◽  
Vol 19 (5) ◽  
pp. 726-736
Author(s):  
Viprabha Kakekochi ◽  
Sathish Chatnahalli Gangadharappa ◽  
Nikhil P. P. ◽  
Chandrasekharan Keloth ◽  
Ezequiel Wolcan ◽  
...  
Keyword(s):  
Excited State ◽  
Conjugated Polymer ◽  
Photon Absorption ◽  
Pyridine Derivatives ◽  
Facile Synthesis ◽  
Absorption Properties ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Donor Acceptor ◽  
Limiting Threshold

Diagrammatic representation of excited state assisted two-photon absorption (2PA) behavior of a donor–acceptor type conjugated polymer (P2TPy) exhibiting an extremely low optical limiting threshold.

Facile Synthesis of 3-(Succinimid-3-yl)-2-oxo-2,3-dihydroimidazo[1,2-a]pyridine Derivatives by Sequential Intra- and Intermolecular Michael Reactions between 2-Aminopyridines and Maleimides

Heterocycles ◽  
2011 ◽  
Vol 83 (1) ◽  
pp. 47 ◽  
Author(s):  
Tetsuro Shimo ◽  
Tomoko Itoh ◽  
Yasutaka Araki ◽  
Tetsuo Iwanaga ◽  
Teruo Shinmyozu ◽  
...  
Keyword(s):  
Pyridine Derivatives ◽  
Facile Synthesis ◽  
Michael Reactions
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