ChemInform Abstract: Asymmetric Synthesis of α-Amino Acids via Homologation of Ni(II) Complexes of Glycine Schiff Bases. Part 2. Aldol, Mannich Addition Reactions, Deracemization and (S) to (R) Interconversion of α-Amino Acids

ChemInform ◽  
2013 ◽  
Vol 44 (51) ◽  
pp. no-no
Author(s):  
Alexander E. Sorochinsky ◽  
Jose Luis Acena ◽  
Hiroki Moriwaki ◽  
Tatsunori Sato ◽  
Vadim Soloshonok
Keyword(s):  
Amino Acids ◽  
Asymmetric Synthesis ◽  
Schiff Bases ◽  
Addition Reactions

ChemInform Abstract: Asymmetric Synthesis of α-Amino Acids via Homologation of Ni(II) Complexes of Glycine Schiff Bases. Part 1. Alkyl Halide Alkylations

ChemInform ◽  
2013 ◽  
Vol 44 (46) ◽  
pp. no-no
Author(s):  
Alexander E. Sorochinsky ◽  
Jose Luis Acena ◽  
Hiroki Moriwaki ◽  
Tatsunori Sato ◽  
Vadim A. Soloshonok
Keyword(s):  
Amino Acids ◽  
Asymmetric Synthesis ◽  
Schiff Bases ◽  
Alkyl Halide

Asymmetric synthesis of threonine and retroracemization of amino acids using Ni(II) complexes of Schiff bases with S-2-n-(N?-benzylprolyl)aminobenzaldehyde

1984 ◽  
Vol 33 (4) ◽  
pp. 738-746 ◽  
Author(s):  
Yu. N. Belokon' ◽  
N. I. Chernoglazova ◽  
K. A. Kochetkov ◽  
N. S. Garbalinskaya ◽  
M. G. Ryzhov ◽  
...  
Keyword(s):  
Amino Acids ◽  
Asymmetric Synthesis ◽  
Schiff Bases

scholarly journals Asymmetric Synthesis of Tailor-Made Amino Acids Using Chiral Ni(II) Complexes of Schiff Bases. An Update of the Recent Literature

Molecules ◽  
2020 ◽  
Vol 25 (12) ◽  
pp. 2739 ◽  
Author(s):  
Yupiao Zou ◽  
Jianlin Han ◽  
Ashot S. Saghyan ◽  
Anna F. Mkrtchyan ◽  
Hiroyuki Konno ◽  
...  
Keyword(s):  
Amino Acids ◽  
Asymmetric Synthesis ◽  
Schiff Bases ◽  
Recent Literature ◽  
Review Article ◽  
Structural Components ◽  
Research Activity ◽  
Tridentate Ligands ◽  
Structural Types ◽  
Controlled Preparation

Tailor-made amino acids are indispensable structural components of modern medicinal chemistry and drug design. Consequently, stereo-controlled preparation of amino acids is the area of high research activity. Over last decade, application of Ni(II) complexes of Schiff bases derived from glycine and chiral tridentate ligands has emerged as a leading methodology for the synthesis of various structural types of amino acids. This review article summarizes examples of asymmetric synthesis of tailor-made α-amino acids via the corresponding Ni(II) complexes, reported in the literature over the last four years. A general overview of this methodology is provided, with the emphasis given to practicality, scalability, cost-structure and recyclability of the chiral tridentate ligands.

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