ChemInform Abstract: A Paal-Knorr Approach to 3,4-Diaryl-Substituted Pyrroles: Facile Synthesis of Lamellarins O and Q.

ChemInform ◽  
2013 ◽  
Vol 44 (7) ◽  
pp. no-no
Author(s):  
Armando Ramirez-Rodriguez ◽  
Jose M. Mendez ◽  
Cristina C. Jimenez ◽  
Fernando Leon ◽  
Alfredo Vazquez
2009 ◽  
Vol 50 (39) ◽  
pp. 5445-5448 ◽  
Author(s):  
Sonya Rivera ◽  
Debasish Bandyopadhyay ◽  
Bimal K. Banik

2012 ◽  
Vol 90 (2) ◽  
pp. 214-221 ◽  
Author(s):  
Wenteng Chen ◽  
Jiaan Shao ◽  
Zhi Li ◽  
Marc A. Giulianotti ◽  
Yongping Yu

A facile synthesis of polysubstituted pyrroles from tosylmethyl isocyanide (TOSMIC) and readily synthesized vinyl azides was developed. The reaction proceeded under mild conditions in the presence of base. 2-Tosyl-substituted pyrroles were obtained in moderate to good isolated yields. Additionally, a base-initiated one-pot pyrrole synthesis also was developed using carboxaldehydes, ethyl 2-azidoacetate, and TOSMIC.


ChemInform ◽  
2010 ◽  
Vol 26 (36) ◽  
pp. no-no
Author(s):  
Y. FANG ◽  
D. LEYSEN ◽  
H. C. J. OTTENHEIJM

1995 ◽  
Vol 25 (12) ◽  
pp. 1857-1861 ◽  
Author(s):  
Y. Fang ◽  
D. Leysen ◽  
H. C. J. Ottenheijm

Author(s):  
Tongyan Yu ◽  
Fei Ji ◽  
Daichuan Huang ◽  
Ya Gao ◽  
Zhaoping Shi ◽  
...  

Given the importance of pyrroles in pharmaceuticals, agrochemicals and functional materials, development of efficient strategies for their construction continues to be the hot area. Here, we present a novel BF3·Et2O...


Synthesis ◽  
2012 ◽  
Vol 44 (21) ◽  
pp. 3321-3326 ◽  
Author(s):  
Alfredo Vazquez ◽  
Armando Ramírez-Rodríguez ◽  
José Méndez ◽  
Cristina Jiménez ◽  
Fernando León

2019 ◽  
Vol 14 (8) ◽  
pp. 828-830 ◽  
Author(s):  
Weihua Meng ◽  
Weihong Wu ◽  
Weiwei Zhang ◽  
Luyao Cheng ◽  
Yunhong Jiao ◽  
...  

Synlett ◽  
1991 ◽  
Vol 1991 (09) ◽  
pp. 725-727 ◽  
Author(s):  
Takeshi Shimizu ◽  
Sayoko Hiranuma ◽  
Zhao-hui Qian ◽  
Hirosuke Yoshioka

2015 ◽  
Vol 12 (1) ◽  
pp. 3910-3918 ◽  
Author(s):  
Dr Remon M Zaki ◽  
Prof Adel M. Kamal El-Dean ◽  
Dr Nermin A Marzouk ◽  
Prof Jehan A Micky ◽  
Mrs Rasha H Ahmed

 Incorporating selenium metal bonded to the pyridine nucleus was achieved by the reaction of selenium metal with 2-chloropyridine carbonitrile 1 in the presence of sodium borohydride as reducing agent. The resulting non isolated selanyl sodium salt was subjected to react with various α-halogenated carbonyl compounds to afford the selenyl pyridine derivatives 3a-f  which compounds 3a-d underwent Thorpe-Ziegler cyclization to give 1-amino-2-substitutedselenolo[2,3-b]pyridine compounds 4a-d, while the other compounds 3e,f failed to be cyclized. Basic hydrolysis of amino selenolo[2,3-b]pyridine carboxylate 4a followed by decarboxylation furnished the corresponding amino selenolopyridine compound 6 which was used as a versatile precursor for synthesis of other heterocyclic compound 7-16. All the newly synthesized compounds were established by elemental and spectral analysis (IR, 1H NMR) in addition to mass spectra for some of them hoping these compounds afforded high biological activity.


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