ChemInform Abstract: Discovery and Application of Iminotriphenylphosphorane as a Formal Aromatic Primary Amine Protecting Group.

ChemInform ◽  
2013 ◽  
Vol 44 (3) ◽  
pp. no-no
Author(s):  
Benedicte Delouvrie ◽  
Herve Germain ◽  
Craig S. Harris ◽  
Maryannick Lamorlette ◽  
Honorine Lebraud ◽  
...  
Keyword(s):  
Primary Amine ◽  
Protecting Group ◽  
Aromatic Primary Amine

Discovery and application of iminotriphenylphosphorane as a formal aromatic primary amine protecting group

2012 ◽  
Vol 53 (40) ◽  
pp. 5380-5384 ◽  
Author(s):  
Bénédicte Delouvrié ◽  
Hervé Germain ◽  
Craig S. Harris ◽  
Maryannick Lamorlette ◽  
Honorine Lebraud ◽  
...  
Keyword(s):  
Primary Amine ◽  
Protecting Group ◽  
Aromatic Primary Amine

Silicon in synthesis: stabase adducts - a new primary amine protecting group: alkylation of ethyl glycinate

1981 ◽  
Vol 22 (19) ◽  
pp. 1787-1790 ◽  
Author(s):  
Stevan Djuric ◽  
John Venit ◽  
Philip Magnus
Keyword(s):  
Primary Amine ◽  
Protecting Group

Synthesis, Characterization and Antimicrobial Activities of some Novel 3-(4-Bromobenzyl)-5-(Thiophen-2-yl)-4H-1,2,4-Triazol Derivatives

2016 ◽  
Vol 68 ◽  
pp. 10-17 ◽  
Author(s):  
Ankur A. Kaneria ◽  
Nilesh M. Thumar ◽  
Kartik D. Ladva ◽  
Milan S. Vadodaria
Keyword(s):  
Antimicrobial Activity ◽  
Mass Spectroscopy ◽  
Primary Amine ◽  
Antimicrobial Activities ◽  
Alkyl Aryl ◽  
H Nmr ◽  
Aromatic Primary Amine ◽  
Bacteria And Fungi

A convenient and promising synthesis of 4-(alkyl/aryl)- 3-(4-bromobenzyl)-5-(thiophen-2-yl)-4H-1,2,4-triazol was carried out by the reaction of 2-(4-bromobenzyl)-5-(thiophen-2-yl)-1,3,4-oxadiazole with different aliphatic/aromatic primary amine without any solvent. The newly synthesized compound were characterized by1H NMR, IR and Mass spectroscopy and also screened for their antimicrobial activity against various strains of bacteria and fungi.

scholarly journals 5-Methyl-3,8-di-(2-amino-4-bromophenyl)-4,9-dioxa-1,2,6,7-tetraaza-5λ5-phosphaspiro[4.4]nona-2,7-diene – Synthesis and Preliminary Cytotoxic Screning

2017 ◽  
Author(s):  
Sławomir Kasperowicz ◽  
Jolanta Czerwińska ◽  
Bartosz Majchrzak ◽  
Barbara Tudek ◽  
Adam Mieczkowski
Keyword(s):  
Primary Amine ◽  
Condensation Reaction ◽  
Biological Screening ◽  
Structural Modifications ◽  
Aromatic Primary Amine ◽  
Amine Groups

5-Methyl-3,8-di-(2-amino-4-bromophenyl)-4,9-dioxa-1,2,6,7-tetraaza-5λ5-phosphaspiro[4.4]nona-2,7-diene was obtained in a condensation reaction of 2-amino-5-bromobenzohydrazide and methylphosphonyl dichloride in the presence of triethylamine. An initial biological screening was performed for the obtained product. The synthesized compound possesses two aromatic primary amine groups and two bromine atoms within the structure, which are suitable for further structural modifications.

Regio-, Stereo- and Enantioselective α-Addition of Carbonyl Nucleo-philes to Allenamides Catalyzed by a Synergistic Copper/Enamine System

2020 ◽  
Author(s):  
Rémi Blieck ◽  
Sebastien Lemouzy ◽  
Marc Taillefer ◽  
Florian Monnier
Keyword(s):  
Catalytic System ◽  
Secondary Amine ◽  
Primary Amine ◽  
Synergistic Catalysis ◽  
Enantioselective Addition ◽  
Amine Catalysts

A dual copper/enamine catalytic system is found to enable an intermolecular enantioselective α-addition of various carbonyl nucleophiles to allenamides. Secondary amine catalysts allowed the highly enantioselective addition of aldehydes, while using primary amine catalysts led to the enantioselective addition of ketoester nucleophiles. The process was found to be highly regio-, stereo- and enantio-selective and represented the first allene hydrofunctionalization using an synergistic catalysis involving copper

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