ChemInform Abstract: Synthesis and Antioxidant Activity of a New Class of Bis and Tris Heterocycles.

ChemInform ◽  
2012 ◽  
Vol 43 (52) ◽  
pp. no-no
Author(s):  
Venkatapuram Padmavathi ◽  
Bhumireddy C. Venkatesh ◽  
Akkarapalli Muralikrishna ◽  
Adivireddy Padmaja
Keyword(s):  
Antioxidant Activity ◽  
New Class

scholarly journals Significantly enhanced antioxidant activity of chitosan through chemical modification with coumarins

2019 ◽  
Vol 10 (12) ◽  
pp. 1480-1488 ◽  
Author(s):  
Qing Li ◽  
Lijie Wei ◽  
Jingjing Zhang ◽  
Guodong Gu ◽  
Zhanyong Guo
Keyword(s):  
Antioxidant Activity ◽  
Chemical Modification ◽  
Chitosan Derivatives ◽  
New Class

A new class of chitosan derivatives possessing coumarins was synthesized to improve the antioxidant activity of chitosan.

scholarly journals A New Class of Synthetic Flavonolignan-Like Dimers: Still Few Molecules, but with Attractive Properties

Molecules ◽  
2018 ◽  
Vol 24 (1) ◽  
pp. 108 ◽  
Author(s):  
Valeria Romanucci ◽  
Giovanni Di Fabio ◽  
Armando Zarrelli
Keyword(s):  
Antioxidant Activity ◽  
Medicinal Chemistry ◽  
Biological Response ◽  
Milk Thistle ◽  
Silybum Marianum ◽  
New Class ◽  
Therapeutic Value ◽  
Recent Developments

In recent years, there has been increasing interest in dimeric molecules due to reports of their promising therapeutic value in the treatment of numerous diseases (such as cancer, HIV, Alzheimer’s and, malaria). Many reports in the literature have highlighted the ability of these molecules to interact not only with specific biologic receptors but also to induce a biological response that more than doubles the results of the corresponding monomeric counterpart. In this regard, flavonolignan dimers or simply bi-flavonolignans are an emerging class of dimeric compounds that unlike bi-flavonoids, which are very widespread in nature, consist of synthetic dimers of some flavonolignans isolated from the milk thistle Silybum marianum [L. Gaertn. (Asteraceae)]. This mini-review will discuss recent developments in the synthesis, characterization and antioxidant activity of new families of flavonolignan dimers, in light of emerging medicinal chemistry strategies.

Synthesis and Antioxidant Activity of a New Class of Bis and Tris Heterocycles

2012 ◽  
Vol 345 (9) ◽  
pp. 745-752 ◽  
Author(s):  
Venkatapuram Padmavathi ◽  
Bhumireddy Chinnachennaiahgari Venkatesh ◽  
Akkarapalli Muralikrishna ◽  
Adivireddy Padmaja
Keyword(s):  
Antioxidant Activity ◽  
New Class

Synthesis and antioxidant activity of a new class of pyrazolyl indoles, thiazolyl pyrazolyl indoles

2017 ◽  
Vol 26 (7) ◽  
pp. 1574-1584 ◽  
Author(s):  
Nagarjuna Ummadi ◽  
Sravya Gundala ◽  
Padmavathi Venkatapuram ◽  
Padmaja Adivireddy
Keyword(s):  
Antioxidant Activity ◽  
New Class

scholarly journals Ceria nanoparticles with rhodamine B as a powerful theranostic agent against intracellular oxidative stress

RSC Advances ◽  
2015 ◽  
Vol 5 (97) ◽  
pp. 79423-79432 ◽  
Author(s):  
Nadezda Apostolova ◽  
Susana Rovira-Llopis ◽  
Herme G. Baldoví ◽  
Sergio Navalon ◽  
Abdullah M. Asiri ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Rhodamine B ◽  
Human Cells ◽  
Ceria Nanoparticles ◽  
New Class ◽  
Theranostic Agent ◽  
Intracellular Oxidative Stress

Ceria nanoparticles with rhodamine B (RhB-CeNPs) are a new class of biocompatible nanomaterial with antioxidant activity and sensor capacity against oxidant species both in solution and in human cells.

scholarly journals Isatin Derivatives as a New Class of Aldose Reductase Inhibitors With Antioxidant Activity

2021 ◽  
Author(s):  
Wenchao Liu ◽  
Huan Chen ◽  
Xiaonan Zhang ◽  
Xin Zhang ◽  
Long Xu ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Acetic Acid ◽  
Aldose Reductase ◽  
Acid Group ◽  
Docking Studies ◽  
Side Chain ◽  
New Class ◽  
Aldose Reductase Inhibitors ◽  
Reductase Inhibitors ◽  
Isatin Derivatives

Abstract In this work, isatin was employed as the scaffold to design aldose reductase inhibitors with antioxidant activity. Most of the isatin derivatives were proved to be excellent in the inhibition of aldose reductase (ALR2) with IC 50 values at submicromolar level, and (E)-2-(5-(4-methoxystyryl)-2,3-dioxoindolin-1-yl) acetic acid (9g) was identified as the most effective with an IC 50 value of 0.015 μM. Moreover, compounds 9a-h with styryl side chains at the C5 position of isatin showed potent antioxidant activity. Particularly, the phenolic compound 9h demonstrated similar antioxidant activity with the well-known antioxidant Trolox. Structure-activity relationship and molecular docking studies showed that the acetic acid group at N1 and C5 p-hydroxystyryl side chain were the key structures to increase the aldose reductase inhibitory activity and antioxidant activity.

Antioxidant activity evaluation of alkyl hydroxytyrosyl ethers, a new class of hydroxytyrosol derivatives

2009 ◽  
Vol 115 (1) ◽  
pp. 86-91 ◽  
Author(s):  
Gema Pereira-Caro ◽  
Andrés Madrona ◽  
Laura Bravo ◽  
José Luis Espartero ◽  
Felipe Alcudia ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
New Class ◽  
Activity Evaluation

Heteroring Annulated Benzimidazolinone Condensed Azepinone Derivatives: A New Class of Highly Potent Antioxidants

2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Neha Garg ◽  
Priyanka Jain ◽  
D. Kishore
Keyword(s):  
Antioxidant Activity ◽  
New Class ◽  
Antioxidant Agents ◽  
Dpph Method

A new class of benzimidazolinone condensed azepinone derivatives annulated on its face “d” with pyrazole, isoxazole, pyrimidine, benzodiazepine, and benzothiazepine nucleus in 3–8, respectively, have been evaluated for their antioxidant activity by DPPH method. Results indicate these to belong to a novel class of highly potent antioxidant agents.

Synthesis and antioxidant activity of a new class of sulfone/sulfonamide-linked bis(oxadiazoles), bis(thiadiazoles), and bis(triazoles)

2014 ◽  
Vol 24 (5) ◽  
pp. 2011-2020 ◽  
Author(s):  
Adivireddy Padmaja ◽  
Devanaboina Pedamalakondaiah ◽  
Gundala Sravya ◽  
Guda Mallikarjuna Reddy ◽  
Malaka Venkateshwarulu Jyothi Kumar
Keyword(s):  
Antioxidant Activity ◽  
New Class
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