ChemInform Abstract: Malonate-Type Bis(oxazoline) Ligands with sp2Hybridized Bridge Carbon: Synthesis and Application in Friedel-Crafts Alkylation and Allylic Alkylation.

ChemInform ◽  
2012 ◽  
Vol 43 (15) ◽  
pp. no-no
Author(s):  
Hongliang Chen ◽  
Fengpei Du ◽  
Lei Liu ◽  
Jing Li ◽  
Qiuying Zhao ◽  
...  
Keyword(s):  
Allylic Alkylation ◽  
Oxazoline Ligands ◽  
Bridge Carbon

Malonate-type bis(oxazoline) ligands with sp2 hybridized bridge carbon: synthesis and application in Friedel–Crafts alkylation and allylic alkylation

Tetrahedron ◽  
2011 ◽  
Vol 67 (49) ◽  
pp. 9602-9608 ◽  
Author(s):  
Hongliang Chen ◽  
Fengpei Du ◽  
Lei Liu ◽  
Jing Li ◽  
Qiuying Zhao ◽  
...  
Keyword(s):  
Allylic Alkylation ◽  
Oxazoline Ligands ◽  
Bridge Carbon

Chiral tetrathiafulvalene based phosphine- and thiomethyl-oxazoline ligands. Evaluation in palladium catalysed asymmetric allylic alkylation

Tetrahedron ◽  
2006 ◽  
Vol 62 (51) ◽  
pp. 11942-11947 ◽  
Author(s):  
Céline Réthoré ◽  
Isabelle Suisse ◽  
Francine Agbossou-Niedercorn ◽  
Eva Guillamón ◽  
Rosa Llusar ◽  
...  
Keyword(s):  
Allylic Alkylation ◽  
Asymmetric Allylic Alkylation ◽  
Oxazoline Ligands

Chiral Phosphaalkene−Oxazoline Ligands for the Palladium-Catalyzed Asymmetric Allylic Alkylation

2010 ◽  
Vol 12 (20) ◽  
pp. 4667-4669 ◽  
Author(s):  
Julien Dugal-Tessier ◽  
Gregory R. Dake ◽  
Derek P. Gates
Keyword(s):  
Allylic Alkylation ◽  
Asymmetric Allylic Alkylation ◽  
Palladium Catalyzed ◽  
Oxazoline Ligands

scholarly journals Spiro Indane-Based Phosphine-Oxazolines as Highly Efficient P,N Ligands for Enantioselective Pd-Catalyzed Allylic Alkylation of Indoles and Allylic Etherification

Molecules ◽  
2019 ◽  
Vol 24 (8) ◽  
pp. 1575 ◽  
Author(s):  
Zhongxuan Qiu ◽  
Rui Sun ◽  
Kun Yang ◽  
Dawei Teng
Keyword(s):  
Aliphatic Alcohols ◽  
Allylic Alkylation ◽  
Indole Derivatives ◽  
Broad Scope ◽  
Palladium Catalyzed ◽  
Allylic Etherification ◽  
High Yields ◽  
Stereogenic Center ◽  
Optimized Conditions ◽  
Oxazoline Ligands

A series of indane-based phosphine-oxazoline ligands with a spirocarbon stereogenic center were examined for palladium-catalyzed asymmetric allylic alkylation of indoles. Under optimized conditions, high yields (up to 98%) and enantioselectivities (up to 98% ee) were obtained with a broad scope of indole derivatives. The ligand was determined to be the most efficient P,N-ligand for this reaction. Moreover, the ligand was also efficient for Pd-catalyzed asymmetric allylic etherification with hard aliphatic alcohols as nucleophiles.

Synthesis of highly rigid phosphine–oxazoline ligands for palladium-catalyzed asymmetric allylic alkylation

2018 ◽  
Vol 16 (41) ◽  
pp. 7717-7724 ◽  
Author(s):  
Zhongxuan Qiu ◽  
Rui Sun ◽  
Dawei Teng
Keyword(s):  
Catalytic Performance ◽  
Allylic Alkylation ◽  
Asymmetric Allylic Alkylation ◽  
Palladium Catalyzed ◽  
Alkylation Reactions ◽  
Stereogenic Center ◽  
Oxazoline Ligands ◽  
Excellent Catalytic Performance

Rigid phosphine–oxazoline ligands with a spirocarbon stereogenic center were developed, which exhibited excellent catalytic performance for Pd-catalyzed allylic alkylation reactions.

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