ChemInform Abstract: Unprecedented C-2 Arylation of Indole with Diazonium Salts: Syntheses of 2,3-Disubstituted Indoles and their Antimicrobial Activity.

ChemInform ◽  
2011 ◽  
Vol 43 (2) ◽  
pp. no-no
Author(s):  
Igor V. Magedov ◽  
et al. et al.
Keyword(s):  
Antimicrobial Activity ◽  
Diazonium Salts

scholarly journals Unprecedented C-2 arylation of indole with diazonium salts: Syntheses of 2,3-disubstituted indoles and their antimicrobial activity

2011 ◽  
Vol 21 (16) ◽  
pp. 4720-4723 ◽  
Author(s):  
Seth Daly ◽  
Kathryn Hayden ◽  
Indranil Malik ◽  
Nikki Porch ◽  
Hong Tang ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Diazonium Salts

scholarly journals Synthesis and Antimicrobial Activity of Newer Quinazolinones

2006 ◽  
Vol 3 (2) ◽  
pp. 97-102 ◽  
Author(s):  
J. A. Patel ◽  
B. D. Mistry ◽  
K. R. Desai
Keyword(s):  
Antimicrobial Activity ◽  
Diazonium Salts ◽  
Alkyl Aryl

2–alkyl–6–bromo–3,1–benzoxazine–4–one (2) is synthesized by treatingp–Bromoanthranilic acid and Acetylechoride or Benzoylchloride. Reaction of 2–alkyl–6–bromo–3,1–benzoxazine–4–one (2). with hydrazinehydrate furnish the corresponding 3–Amino–2–methyl–6–bromoquinazoline–4(3H)–one (3) which on reaction with benzaldehyde affordN,N– arylidene derivative (4). Reaction of 4 with various diazonium salts yields 6–bromo–2–alkyl/aryl–3{[phenyl(phenyldiazenyl)methylene]amino}quinazolin–4(3H)–one .

scholarly journals Design, Synthesis, and Antimicrobial Evaluation of Novel Pyrazoles and Pyrazolyl 1,3,4-Thiadiazine Derivatives

Molecules ◽  
2018 ◽  
Vol 23 (9) ◽  
pp. 2092 ◽  
Author(s):  
Ibrahim Radini
Keyword(s):  
Antimicrobial Activity ◽  
Minimum Inhibitory Concentration ◽  
Elemental Analysis ◽  
Inhibitory Concentration ◽  
Diazonium Salts ◽  
Design Synthesis ◽  
Antifungal Activities ◽  
Antibacterial And Antifungal Activities ◽  
Antimicrobial Evaluation ◽  
Antibacterial And Antifungal

A novel series of pyrazolyl 1,3,4-thiadiazines 5a–c, 8a–c, 12, 15a–c, 17a–c, and 20 was prepared from the reaction of pyrazole-1-carbothiohydrazide 1a,b with 2-oxo-N′-arylpropanehydrazonoyl chloride, 2-chloro-2-(2-arylhydrazono)acetate, and 3-bromoacetylcoumarin. Moreover, the regioselective reaction of 5-pyrazolone-1-carbothiohydrazide 1a with 4-substituted diazonium salts and 4-(dimethylamino)benzaldehyde gave the corresponding hydrazones 21a–c and 22. The newly prepared compounds were characterized by spectroscopy and elemental analysis. Many new synthesized compounds showed considerable antimicrobial activity against tested microorganisms. Hydrazones 21a–c and 22 showed remarkable antibacterial and antifungal activities. 4-(2-(p-tolyl)hydrazineylidene)-pyrazole-1-carbothiohydrazide 21a displayed the highest antibacterial and antifungal activities with minimum inhibitory concentration (MIC) values lower than standard drugs chloramphenicol and clotrimazole, in the range of 62.5–125 and 2.9–7.8 µg/mL, respectively.

Synthesis and Antimicrobial Activity of Thiocyanatoarylation Products of Acrylamide and Methacrylamide by Diphenyl- and Phenylene-Bis-Diazonium Salts

2016 ◽  
Vol 50 (8) ◽  
pp. 534-536 ◽  
Author(s):  
B. D. Grishchuk ◽  
V. N. Yatsyuk ◽  
V. S. Baranovskii ◽  
E. V. Pokryshko ◽  
S. I. Klimnyuk
Keyword(s):  
Antimicrobial Activity ◽  
Diazonium Salts

scholarly journals Synthesis and antimicrobial activity of 4-(5-ARYL-2-FUROYL)morpholines and 4-[(5-ARYL-2-FURYL)carbonothioyl] morpholines

Pharmacia ◽  
2021 ◽  
Vol 68 (1) ◽  
pp. 175-179
Author(s):  
Yuliia Matiichuk ◽  
Yuri Gorak ◽  
Roman Martyak ◽  
Taras Chaban ◽  
Volodymyr Ogurtsov ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Nmr Spectroscopy ◽  
High Activity ◽  
Carboxylic Acids ◽  
Elemental Analysis ◽  
Spectroscopic Data ◽  
Antimicrobial Activities ◽  
Diazonium Salts ◽  
H Nmr ◽  
New Compounds

By the reaction of furan-2-carboxylic acids and furfural with diazonium salts 1a-j the arylfuran-2-carboxylic acids 4a-e and 5-arylfuran-2-carbaldehydes 5a-f were synthesized. Acids 4a-e were transformed into appropriated acylchlorides 6a-e and were used for preparation of 4-(5-aryl-2-furoyl)morpholines 7a-e. 4-[(5-Aryl-2-furyl)carbonothioyl]morpholines 8a-f were prepared from aldehydes 5a-f by using Willgerodt-Kindler reaction. The structures of the obtained compounds were confirmed by 1H NMR spectroscopy and elemental analysis. All these new compounds gave spectroscopic data in accordance with the proposed structures. The antimicrobial activities of synthesized compounds 7a-e and 8a-f were investigated and the compounds with high activity against C. neoformans ATCC 208821 were identified.

Antimicrobial activity of withanolides from the leaves of Withania aristata

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
L Araujo ◽  
N Padilla ◽  
GG Llanos ◽  
IL Bazzocchi ◽  
L Moujir
Keyword(s):  
Antimicrobial Activity

Antimicrobial activity of Eurycoma longifolia and Momordica charantia

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
R Łos ◽  
K Skalicka-Wozniak ◽  
J Widelski ◽  
A Malm ◽  
K Głowniak
Keyword(s):  
Antimicrobial Activity ◽  
Momordica Charantia ◽  
Eurycoma Longifolia

Antioxidant and antimicrobial activity of willow herb (Epilobium angustifolium L.)

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
I Kosalec ◽  
M Zovko ◽  
K Sankovic ◽  
D Kremer ◽  
S Pepeljnjak
Keyword(s):  
Antimicrobial Activity ◽  
Epilobium Angustifolium ◽  
Antioxidant And Antimicrobial Activity
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