ChemInform Abstract: Multicomponent Reactions Stereo- and Regioselective Three-Component Reaction in Water: Synthesis of Triazole Substituted β-Lactams via Click Chemistry.

ChemInform ◽  
2011 ◽  
Vol 42 (34) ◽  
pp. no-no
Author(s):  
Ming Lei ◽  
Wang-Ze Song ◽  
Zu-Jin Zhan ◽  
Sun-Liang Cui ◽  
Fang-Rui Zhong
ChemInform ◽  
2005 ◽  
Vol 36 (52) ◽  
Author(s):  
Ze-Yi Yan ◽  
Ya-Bin Zhao ◽  
Ming-Jin Fan ◽  
Wei-Min Liu ◽  
Yong-Min Liang

Synthesis ◽  
2018 ◽  
Vol 50 (05) ◽  
pp. 1123-1132 ◽  
Author(s):  
Jürgen Martens ◽  
Torben Schlüter ◽  
Nils Frerichs ◽  
Marc Schmidtmann

This work describes the synthesis of compounds containing thiazolidine and propargylamidic motifs. Their preparation follows a synthetic route containing two multicomponent reactions. First, the Asinger four-component reaction is used to prepare 3-thiazolines and 3-oxazolines. Secondly, these heterocyclic imines are converted into propargylamides by a copper-catalyzed three-component reaction using acyl chlorides and terminal alkynes. The synthetic route is characterized by mild conditions and many functional groups are tolerated. The formation of an unexpected α-alkynoxyamide is also presented.


2012 ◽  
Vol 53 (52) ◽  
pp. 7088-7092 ◽  
Author(s):  
Mohammad Ali Rasouli ◽  
Mohammad Mahdavi ◽  
Parviz Rashidi Ranjbar ◽  
Mina Saeedi ◽  
Abbas Shafiee ◽  
...  

ChemInform ◽  
2013 ◽  
Vol 44 (14) ◽  
pp. no-no
Author(s):  
Mohammad Ali Rasouli ◽  
Mohammad Mahdavi ◽  
Parviz Rashidi Ranjbar ◽  
Mina Saeedi ◽  
Abbas Shafiee ◽  
...  

Author(s):  
Thi Thi Xuan Luu ◽  
Vinh Quang Pham

Multicomponent reactions (MCRs) play an important role to create the molecular complexity in a one-step process. Based on the mechanism and process of Mannich-type reactions in the synthesis of Grammin, arylthiomethylation reactions of indole were performed by using three components: indole, p-thiocresol and a solution of formaldehyde (36%) under two activation conditions, e.g. magnetic stirring and ultrasonic irradiation. The main product, 3-(p-tolylthiomethyl)-1H-indole, was obtained in a moderate yield (54%) under short irradiation (40 minutes) by probe sonicator.


RSC Advances ◽  
2014 ◽  
Vol 4 (29) ◽  
pp. 15319-15324 ◽  
Author(s):  
Shaik Karamthulla ◽  
Suman Pal ◽  
Tasneem Parvin ◽  
Lokman H. Choudhury

Three component reaction of 2-hydroxy 1,4-naphthoquinones, aldehydes, and aminopyrazoles in the presence of a catalytic amount ofl-proline has been described for the synthesis of a series of 2H-benzo[g]pyrazolo[3,4-b]quinoline-5,10(4H,11H)-dione derivatives.


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