ChemInform Abstract: Cellular and Molecular Actions of Methylene Blue in the Nervous System

ChemInform ◽  
2011 ◽  
Vol 42 (16) ◽  
pp. no-no ◽  
Author(s):  
Murat Oz ◽  
Dietrich E. Lorke ◽  
Mohammed Hasan ◽  
George A. Petroianu
Keyword(s):  
Methylene Blue ◽  
Nervous System

scholarly journals Unna's Polychrome Methylene Blue Method

1899 ◽  
Vol 45 (190) ◽  
pp. 466-468
Author(s):  
T. Aldous Clinch
Keyword(s):  
Central Nervous System ◽  
Methylene Blue ◽  
Nervous System ◽  
The Central Nervous System

In the Neurologisches Centralblatt for July 15th, 1898, Drs. Luithleu and Sorgo describe a method of staining the central nervous system, which at that time I believed to be new. However, Dr. Wright, in the summer number of Brain for the same year, and therefore about the same time, referred to, without describing the same method, so that it is obvious that it had already claimed some attention from neurologists.

On the Nervous Control of the Velar Cilia of the Nudibranch Veliger

1926 ◽  
Vol 4 (1) ◽  
pp. 1-26 ◽  
Author(s):  
G. S. CARTER
Keyword(s):  
Methylene Blue ◽  
Nervous System ◽  
Recent Work ◽  
Acid Medium ◽  
Alkaline Medium ◽  
Outer Surface ◽  
Ciliated Cell ◽  
Nerve Endings ◽  
Nerve Tissue ◽  
Nervous Control

(1) The beat of the velar cilia of the Nudibranch veliger is intermittent and appears to be under the control of the organism. (2) Fibres lying between the cells which bear the velar cilia are described. They end near the outer surface of these cells in fibrils which resemble those of the muscle-plate in structure. They stain with specific nerve-stains and were shown to be in all probability continuous with nerves lying deeper in the tissues. It is concluded that these are nerve-fibrils. (3) Within the ciliated cell at the level of the terminal fibrils of these fibres there is a layer of granules which stain with methylene blue. (4) The cilia of cells which have been separated from the tissues beat actively but the beat is continuous and not intermittent. (5) In the presence of various narcotics the intermissions are inhibited more quickly than the beat of the cilia is affected and at a lower concentration of the drug. (6) Some drugs which are not known to act as narcotics were used and with certain exceptions, which are discussed, did not have this effect. (7) In an acid medium the beat is slower but the intermissions continue so long as the cilia beat. (8) In an alkaline medium the intermissions are inhibited before the beat is affected. This is discussed and it is suggested that it is in accordance with recent work on the effect of changes in the reaction of the medium on nerve-tissue. (9) It is concluded that the nerve-endings found among these cells are regulatory and are concerned in the causation of the intermissions. The beat of the cilia is therefore under the control of the nervous system of the animal.

scholarly journals IV. Some points in the histology of the nervous system of the embryonic lobster

1894 ◽  
Vol 55 (331-335) ◽  
pp. 407-414 ◽  
Keyword(s):  
Methylene Blue ◽  
Nervous System ◽  
Present Communication ◽  
Thoracic Ganglia ◽  
The Common

The following observations have been made on late embryos of the common lobster ( Homarus vulgaris ) by means of Ehrlich’s methylene blue method, as modified by Biedermann and Apáthy. The results to be recorded in the present communication apply chiefly to the thoracic ganglia, which in the embryo are fused into one mass. The nerve elements, which have stained, may be divided into three main groups:— I. Elements of which both the cell and the fibre lie entirely in the ganglionic chain, and which must be supposed to serve the purpose of co-ordinating the action of its various parts.

scholarly journals HEME OXYGENASE-2 NEURONS BRAIN AND SPINAL CORD OF HUMAN

2012 ◽  
Vol 67 (6) ◽  
pp. 36-41 ◽  
Author(s):  
V. M. Chertok ◽  
A. E. Kotsyuba ◽  
E. P. Kotsyuba
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Methylene Blue ◽  
Nervous System ◽  
Brain Stem ◽  
Heme Oxygenase ◽  
Enzyme Reaction ◽  
Brain And Spinal Cord ◽  
The Brain ◽  
Number Of Cells

Immune localization of heme oxygenase-2 in neurons of some nuclei of the spinal cord and brain stem in 6 men 18–44 years old who died from causes unrelated to injury of central nervous system was studied. Neurons with positive reaction are determined for all studied regions of the brain where their contents in various nuclei ranging from 0,5 to 16% of the total number of cells detected by methylene blue. In all the sensory nuclei there is a high proportion of small neurons with a high or moderate density of reaction produc deposits. Large cells of motor nuclei often exhibit negative or low intensive enzyme reaction. 

The Location of Penetration Barriers in the Ganglia of the American Cockroach, Periplaneta Americana (L.)

1968 ◽  
Vol 48 (2) ◽  
pp. 325-338
Author(s):  
M. E. ELDEFRAWI ◽  
A. TOPPOZADA ◽  
M. M. SALPETER ◽  
R. D. O'BRIEN
Keyword(s):  
Methylene Blue ◽  
Nervous System ◽  
Nerve Cord ◽  
Periplaneta Americana ◽  
Slow Component ◽  
Fast Component ◽  
American Cockroach ◽  
Fat Tissue ◽  
Special Protection ◽  
Nerve Cords

1. The nature and location of the barrier system which partially protects the nervous system in insects has been investigated in the American cockroach by studying the fluxes of 14C-butanol, 14C-butyrate, 14C-butylamine and 3H-butyltrimethylammonium. 2. Disruption of the sheath covering the ganglia has little effect on the influx of butanol and butyrate, but increased that of butylamine and butyltrimethylammonium. 3. 2,4-Dinitrophenol slowed the influx of only those compounds whose metabolism it blocks. 4. Effluxes show a fast and a slow component. Disruption of the sheath increases the amount but not the rate of the fast component; it raises the rate of the slow component for butanol, butyrate and butyltrimethylammonium, but not always. 5. Nerve cords stained with methylene blue and freeze-sectioned show dye concentrated in the fat tissue surrounding the nerve cord, then in the neural lamella; a little penetrated the cell bodies of glia and neurones, but the neuropile was unstained. 6. These findings suggest that the external sheath plays some part in restricting cation influx; apart from this the barrier system is a function of the whole ganglion, except that the neuropile may enjoy special protection.

Intravenous Methylene Blue: a New Method for Studying the Nervous System

Nature ◽  
1948 ◽  
Vol 161 (4087) ◽  
pp. 318-319 ◽  
Author(s):  
W. H. FEINDEL ◽  
D. C. SINCLAIR ◽  
G. WEDDELL
Keyword(s):  
Methylene Blue ◽  
Nervous System ◽  
New Method

Nerve Elements of the Embryonic Lobster

1894 ◽  
Vol 3 (3) ◽  
pp. 208-209
Author(s):  
Edgar J. Allen
Keyword(s):  
Methylene Blue ◽  
Nervous System ◽  
Dilute Solutions ◽  
Large Size ◽  
Decapod Crustacea ◽  
The Common ◽  
The Individual

After repeated trials with dilute solutions of methylene blue upon larvæ and embryos of a number of the smaller decapod Crustacea, a favourable object for the study of the nervous system was at last found in the embryo of the common lobster. The embryos of this animal are specially advantageous on account of their large size, which enables them to be readily manipulated without much damage being done to their tissues, and also on account of the large size of the individual nerve elements.

scholarly journals Cellular and molecular actions of Methylene Blue in the nervous system

2010 ◽  
Vol 31 (1) ◽  
pp. 93-117 ◽  
Author(s):  
Murat Oz ◽  
Dietrich E. Lorke ◽  
Mohammed Hasan ◽  
George A. Petroianu
Keyword(s):  
Methylene Blue ◽  
Nervous System
Sign in / Sign up

Export Citation Format

Share Document