ChemInform Abstract: Iron/Acetic Acid Mediated Carbon Degradation: A Facile Route for the Synthesis of Quinoline Derivatives.

ChemInform ◽  
2010 ◽  
Vol 42 (3) ◽  
pp. no-no
Author(s):  
Chintakunta Ramesh ◽  
Veerababurao Kavala ◽  
Chun-Wei Kuo ◽  
Ching-Fa Yao
2010 ◽  
Vol 51 (40) ◽  
pp. 5234-5237 ◽  
Author(s):  
Chintakunta Ramesh ◽  
Veerababurao Kavala ◽  
Chun-Wei Kuo ◽  
Ching-Fa Yao

ACS Omega ◽  
2018 ◽  
Vol 3 (1) ◽  
pp. 1126-1136 ◽  
Author(s):  
Liang Chen ◽  
Rong Huang ◽  
Ling-Bin Kong ◽  
Jun Lin ◽  
Sheng-Jiao Yan

Synthesis ◽  
2017 ◽  
Vol 50 (06) ◽  
pp. 1350-1358 ◽  
Author(s):  
Cunde Wang ◽  
Xushun Qing ◽  
Ting Wang ◽  
Chenlu Dai ◽  
Zhenjie Su

An efficient iron/acetic acid system-mediated reductive cyclization reaction of substituted 2-aryl-3-nitro-2H-chromenes with substituted 2-nitrobenzaldehydes for the synthesis of 6-aryl-6H-chromeno[3,4-b]quinolines was developed. This reaction involves the sequential reduction, hydrolysis, aldol condensation, intramolecular addition, and the nucleophilic addition of substituted 2-aryl-3-nitro-2H-chromenes with substituted 2-nitrobenzaldehydes to give the corresponding 6H-chromeno[3,4-b]quinolines. This transformation provides a straightforward synthetic protocol for constructing substituted 6H-chromeno[3,4-b]quinoline derivatives. The structures of three typical products were confirmed by X-ray crystallography.


ChemInform ◽  
2005 ◽  
Vol 36 (8) ◽  
Author(s):  
A. A. Avetisyan ◽  
I. L. Aleksanyan ◽  
A. A. Pivazyan

Tetrahedron ◽  
2011 ◽  
Vol 67 (6) ◽  
pp. 1187-1192 ◽  
Author(s):  
Chintakunta Ramesh ◽  
B. Rama Raju ◽  
Veerababurao Kavala ◽  
Chun-Wei Kuo ◽  
Ching-Fa Yao

1984 ◽  
Vol 49 (11) ◽  
pp. 2628-2634 ◽  
Author(s):  
Jan Slouka ◽  
Vojtěch Bekárek ◽  
Karel Nálepa ◽  
Antonín Lyčka

o-Nitrophenylpyruvic acid thiosemicarbazone (I) has been cyclized to 2-thio-5-(o-nitrobenzyl)-6-azauracil (II) which has been transformed in 5-(o-nitrobenzyl)-6-azauracil (III) by both oxidation, and methylation and hydrolysis of the 3-methylmercapto-6-(o-nitrobenzyl)-2,5-dihydro-1,2,4-triazin-5-one (V) formed. Reduction of derivative III with iron(II) hydroxide and cyclization of the amino derivative IV formed gives 2,3,4,10-tetrahydro-1,2,4-triazino[5,6-b]quinolin-3-one (VI). Compound VI is transformed in acid medium to 1-amino-1,2-dihydroimidazo[4,5-b]quinolin-2-one (VIII) via the tautomer VII, and in boiling acetic acid it gives the acetylamino derivative IX. The N-amino derivative VIII reacts with carbonyl compounds to give the corresponding hydrazones X - XII, and its nitrosation gives 1,2-dihydroimidazo[4,5-b]quinolin-2-one (XIII).


Tetrahedron ◽  
2005 ◽  
Vol 61 (16) ◽  
pp. 4035-4041 ◽  
Author(s):  
Pascal Marchand ◽  
Alain Puget ◽  
Guillaume Le Baut ◽  
Peter Emig ◽  
Michael Czech ◽  
...  

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