ChemInform Abstract: Iridium-Catalyzed Coupling Reaction of Primary Alcohols with 2-Alkynes Leading to Hydroacylation Products.

ChemInform ◽  
2010 ◽  
Vol 41 (24) ◽  
pp. no-no
Author(s):  
Shintaro Hatanaka ◽  
Yasushi Obora ◽  
Yasutaka Ishii
Keyword(s):  
Coupling Reaction ◽  
Primary Alcohols

Iridium-Catalyzed Coupling Reaction of Primary Alcohols with 2-Alkynes Leading to Hydroacylation Products

2010 ◽  
Vol 16 (6) ◽  
pp. 1883-1888 ◽  
Author(s):  
Shintaro Hatanaka ◽  
Yasushi Obora ◽  
Yasutaka Ishii
Keyword(s):  
Coupling Reaction ◽  
Primary Alcohols

scholarly journals Carboxylated Chitosan Nanocrystals: Novel Synthetic Route and Application as Superior Support for Gold-Catalyzed Reactions

2020 ◽  
Author(s):  
Tony Jin ◽  
Davis Kurdyla ◽  
Sabahudin Hrapovic ◽  
Alfred Leung ◽  
Sophie Régnier ◽  
...  
Keyword(s):  
Imaging Techniques ◽  
Coupling Reaction ◽  
Primary Alcohols ◽  
X Ray Diffraction ◽  
Catalytic Activities ◽  
Glycosidic Bonds ◽  
Carboxylate Groups ◽  
Transmission Electron ◽  
Nitrophenol Reduction ◽  
Catalyzed Reactions

<p>Chitin nanocrystals (ChNCs) were prepared by partial cleavage of glycosidic bonds in chitin with concurrent oxidation of chitin C6 primary alcohols to produce carboxylate groups on the surface of the ChNCs. Following alkaline deacetylation of the ChNCs in the presence of NaBH<sub>4</sub> to inhibit “end-peeling” afforded chitosan nanocrystals (ChsNCs) with a degree of deacetylation (DDA) >80%. Transmission electron microscopy (TEM), X-ray diffraction (XRD) and Fourier-transform Infrared (FTIR) spectroscopy were used to determine the morphology and composition of these carboxylated ChNCs and ChsNCs. Subsequently, two methods were used to deposit Au onto the nanocrystals, and the catalytic activities of the resulting biomass-based nanocatalysts were tested for the 4-nitrophenol reduction and the aldehyde-amine-alkyne (A<sup>3</sup>) coupling reaction. In particular, Au nanoparticles over ChsNCs featured the highest turnover frequency value for the 4-nitrophenol reduction reported to date. Spectroscopic and imaging techniques confirmed the importance of controlling precisely the redox state of Au as it is being deposited to afford highly disperse active site on the bio-nano-support. </p>

scholarly journals Acetals from primary alcohols with the use of tridentate proton responsive phosphinepyridonate iridium catalysts

RSC Advances ◽  
2016 ◽  
Vol 6 (102) ◽  
pp. 100554-100558 ◽  
Author(s):  
A. R. Sahoo ◽  
F. Jiang ◽  
C. Bruneau ◽  
G. V. M. Sharma ◽  
S. Suresh ◽  
...  
Keyword(s):  
Coupling Reaction ◽  
Primary Alcohols ◽  
Iridium Catalysts ◽  
Metallic Precursor ◽  
Dehydrogenative Coupling

The association of the new phosphinepyridonate ligands along with an iridium metallic precursor resulted in the selective acetalization of various primary alcohols via a formal dehydrogenative coupling reaction.

Synthesis of 2-Hydroxymethyl Ketones by Ruthenium Hydride-Catalyzed Cross-Coupling Reaction of α,β-Unsaturated Aldehydes with Primary Alcohols

2010 ◽  
Vol 12 (1) ◽  
pp. 1-3 ◽  
Author(s):  
Aurélien Denichoux ◽  
Takahide Fukuyama ◽  
Takashi Doi ◽  
Jiro Horiguchi ◽  
Ilhyong Ryu
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Primary Alcohols ◽  
Ruthenium Hydride ◽  
Unsaturated Aldehydes ◽  
Cross Coupling Reaction

Iridium-Catalyzed Coupling Reaction of Primary Alcohols with 1-Aryl-1-propynes Leading to Secondary Homoallylic Alcohols

2009 ◽  
Vol 11 (15) ◽  
pp. 3510-3513 ◽  
Author(s):  
Yasushi Obora ◽  
Shintaro Hatanaka ◽  
Yasutaka Ishii
Keyword(s):  
Coupling Reaction ◽  
Primary Alcohols ◽  
Homoallylic Alcohols

scholarly journals Carboxylated Chitosan Nanocrystals: Novel Synthetic Route and Application as Superior Support for Gold-Catalyzed Reactions

2020 ◽  
Author(s):  
Tony Jin ◽  
Davis Kurdyla ◽  
Sabahudin Hrapovic ◽  
Alfred Leung ◽  
Sophie Régnier ◽  
...  
Keyword(s):  
Imaging Techniques ◽  
Coupling Reaction ◽  
Primary Alcohols ◽  
X Ray Diffraction ◽  
Catalytic Activities ◽  
Glycosidic Bonds ◽  
Carboxylate Groups ◽  
Transmission Electron ◽  
Nitrophenol Reduction ◽  
Catalyzed Reactions

<p>Chitin nanocrystals (ChNCs) were prepared by partial cleavage of glycosidic bonds in chitin with concurrent oxidation of chitin C6 primary alcohols to produce carboxylate groups on the surface of the ChNCs. Following alkaline deacetylation of the ChNCs in the presence of NaBH<sub>4</sub> to inhibit “end-peeling” afforded chitosan nanocrystals (ChsNCs) with a degree of deacetylation (DDA) >80%. Transmission electron microscopy (TEM), X-ray diffraction (XRD) and Fourier-transform Infrared (FTIR) spectroscopy were used to determine the morphology and composition of these carboxylated ChNCs and ChsNCs. Subsequently, two methods were used to deposit Au onto the nanocrystals, and the catalytic activities of the resulting biomass-based nanocatalysts were tested for the 4-nitrophenol reduction and the aldehyde-amine-alkyne (A<sup>3</sup>) coupling reaction. In particular, Au nanoparticles over ChsNCs featured the highest turnover frequency value for the 4-nitrophenol reduction reported to date. Spectroscopic and imaging techniques confirmed the importance of controlling precisely the redox state of Au as it is being deposited to afford highly disperse active site on the bio-nano-support. </p>

Simultaneous Spectrophotometric Determination of Salbutamol by Coupling with Diazotized 4-Aminobenzoic acid

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Hind Hadi ◽  
Gufran Salim
Keyword(s):  
Pharmaceutical Preparations ◽  
Coupling Reaction ◽  
Dosage Forms ◽  
Water Soluble ◽  
Trace Determination ◽  
Aminobenzoic Acid ◽  
Optimum Conditions ◽  
Colored Product ◽  
Versus Concentration

A simple, rapid and sensitive spectrophotmetric method for trace determination of salbutamol (SAL) in aqueous solution and in pharmaceutical preparations is described. The method is based on the diazotization coupling reaction of the intended compound with 4-amino benzoic acid (ABA) in alkaline medium to form an intense orange, water soluble dye that is stable and shows maximum absorption at 410 nm. A graph of absorbance versus concentration indicates that Beer’s law is obeyed over the concentration range of 0.5-30 ppm, with a molar absorbtivity 3.76×104 L.mol-1 .cm-1 depending on the concentration of SAL. The optimum conditions and stability of the colored product have been investigated and the method was applied successfully to the determination of SAL in dosage forms.

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