ChemInform Abstract: An Efficient and Scalable Ritter Reaction for the Synthesis of tert-Butyl Amides.

ChemInform ◽  
2009 ◽  
Vol 40 (29) ◽  
Author(s):  
Jean C. Baum ◽  
Jacqueline E. Milne ◽  
Jerry A. Murry ◽  
Oliver R. Thiel
Keyword(s):  
2012 ◽  
Vol 16 (12) ◽  
pp. 2058-2063 ◽  
Author(s):  
Scott W. Roberts ◽  
Stephen M. Shaw ◽  
Jacqueline E. Milne ◽  
Dawn E. Cohen ◽  
Justin T. Tvetan ◽  
...  

2020 ◽  
Vol 44 (9-10) ◽  
pp. 602-608
Author(s):  
Wanfeng Yang ◽  
Chengliang Feng ◽  
Yuqi Tang ◽  
Min Ji ◽  
Junqing Chen

The utility of Cu(OTf)2 as the catalyst for the synthesis of a series of N- tert-butyl amides in excellent isolated yields via the reaction of nitriles (alkyl, aryl, benzyl, and furyl nitriles) with di- tert-butyl dicarbonate is described. Cu(OTf)2 is a highly stable and efficient catalyst for the present Ritter reaction under solvent-free conditions at room temperature.


2018 ◽  
Vol 3 (29) ◽  
pp. 8501-8504 ◽  
Author(s):  
Chengliang Feng ◽  
Bin Yan ◽  
Wenjin Yao ◽  
Junqing Chen ◽  
Min Ji

ChemInform ◽  
2011 ◽  
Vol 42 (47) ◽  
pp. no-no
Author(s):  
Pankaj Dawar ◽  
M. Bhagavan Raju ◽  
Ramesha A. Ramakrishna

Synlett ◽  
2018 ◽  
Vol 29 (17) ◽  
pp. 2257-2264 ◽  
Author(s):  
Min Ji ◽  
Chengliang Feng ◽  
Bin Yan ◽  
Guibo Yin ◽  
Junqing Chen

An efficient and inexpensive synthesis of N-substituted amides from the Ritter reaction of nitriles with esters catalyzed by Fe(ClO4)3·H2O is described. Fe(ClO4)3·H2O is an economically efficient catalyst for the Ritter reaction under solvent-free conditions. Reactions of a range of esters (benzyl, sec-alkyl, and tert-butyl esters) with nitriles (primary, secondary, tertiary, and aryl nitriles) were performed to provide the corresponding amides in high to excellent yields.


2011 ◽  
Vol 52 (33) ◽  
pp. 4262-4265 ◽  
Author(s):  
Pankaj Dawar ◽  
M. Bhagavan Raju ◽  
Ramesha A. Ramakrishna

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