Mechanistic Insights and Safety Evaluation of the Ritter Reaction Utilizing tert-Butyl Acetate as the tert-Butyl Cation Source

2012 ◽  
Vol 16 (12) ◽  
pp. 2058-2063 ◽  
Author(s):  
Scott W. Roberts ◽  
Stephen M. Shaw ◽  
Jacqueline E. Milne ◽  
Dawn E. Cohen ◽  
Justin T. Tvetan ◽  
...  
Synlett ◽  
2018 ◽  
Vol 29 (17) ◽  
pp. 2257-2264 ◽  
Author(s):  
Min Ji ◽  
Chengliang Feng ◽  
Bin Yan ◽  
Guibo Yin ◽  
Junqing Chen

An efficient and inexpensive synthesis of N-substituted amides from the Ritter reaction of nitriles with esters catalyzed by Fe(ClO4)3·H2O is described. Fe(ClO4)3·H2O is an economically efficient catalyst for the Ritter reaction under solvent-free conditions. Reactions of a range of esters (benzyl, sec-alkyl, and tert-butyl esters) with nitriles (primary, secondary, tertiary, and aryl nitriles) were performed to provide the corresponding amides in high to excellent yields.


2009 ◽  
Vol 82 (6) ◽  
pp. 1025-1028
Author(s):  
Yu. E. Klimko ◽  
S. D. Isaev ◽  
D. A. Pisanenko

1968 ◽  
Vol 21 (11) ◽  
pp. 2809 ◽  
Author(s):  
JW Ducker ◽  
MJ Gunter

ChemInform ◽  
2010 ◽  
Vol 30 (19) ◽  
pp. no-no
Author(s):  
Vladimir A. Glushkov ◽  
Yurii V. Shklyaev ◽  
Valentina I. Sokol ◽  
Vladimir S. Sergienko ◽  
Victor V. Davidov

Sign in / Sign up

Export Citation Format

Share Document