Laboratory Automation with Parallel Synthesis: A Solid Phase Supported Access to New Biogenic Amine Receptor Ligands

ChemInform ◽  
2007 ◽  
Vol 38 (47) ◽  
Author(s):  
Peter Gmeiner
Keyword(s):  
Biogenic Amine ◽  
Solid Phase ◽  
Parallel Synthesis ◽  
Laboratory Automation ◽  
Receptor Ligands ◽  
Biogenic Amine Receptor

A solid phase parallel synthesis of diverse amides as dopamine D3 receptor ligands

2008 ◽  
Vol 23 (5) ◽  
pp. 588-592 ◽  
Author(s):  
Mickaël Jean ◽  
Jacques Renault ◽  
Jean-Claude Camelin ◽  
Nicolas Levoin ◽  
Denis Danvy ◽  
...  
Keyword(s):  
Solid Phase ◽  
Parallel Synthesis ◽  
Dopamine D3 Receptor ◽  
D3 Receptor ◽  
Receptor Ligands ◽  
Dopamine D3

scholarly journals Fluorous methods for synthesis and separation of organic molecules

2000 ◽  
Vol 72 (9) ◽  
pp. 1649-1653 ◽  
Author(s):  
Dennis P. Curran
Keyword(s):  
Organic Molecules ◽  
Solid Phase ◽  
Liquid Extraction ◽  
Parallel Synthesis ◽  
Solution Phase ◽  
Phase Extraction ◽  
Organic Reaction ◽  
Reverse Phase ◽  
Liquid Liquid Extraction ◽  
Fluorous Tag

Fluorous molecules partition out of an organic phase and into a fluorous (highly fluorinated) phase in a liquid-liquid extraction. New fluorous techniques allow simple yet substantive separations of organic reaction mixtures based on the presence or absence of a fluorous tag. Fluorous-tagged molecules can also be separated from nontagged molecules by solid phase extraction over fluorous reverse-phase silica gel. This technique is ideal for solution-phase parallel synthesis because it allows simple yet substantive separations of organic reaction mixtures.

scholarly journals A Traceless Approach for the Solid-Phase Parallel Synthesis of Trisubstituted Oxindoles

2008 ◽  
Vol 10 (5) ◽  
pp. 752-752 ◽  
Author(s):  
Jinwen Xie ◽  
Jing Sun ◽  
Guolin Zhang ◽  
Richard A. Houghten ◽  
Yongping Yu
Keyword(s):  
Solid Phase ◽  
Parallel Synthesis
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