Chiral Borate Esters in Asymmetric Synthesis. Part 5. Chiral Spiroborate Esters Catalyzed Highly Enantioselective Direct Aldol Reaction.

ChemInform ◽  
2006 ◽  
Vol 37 (43) ◽  
Author(s):  
Yan Zhou ◽  
Zixing Shan
Keyword(s):  
Asymmetric Synthesis ◽  
Aldol Reaction ◽  
Direct Aldol Reaction ◽  
Borate Esters

scholarly journals Catalytic asymmetric synthesis of CF3-substituted tertiary propargylic alcohols via direct aldol reaction of α-N3amide

2017 ◽  
Vol 8 (4) ◽  
pp. 3260-3269 ◽  
Author(s):  
Hidetoshi Noda ◽  
Fuyuki Amemiya ◽  
Karin Weidner ◽  
Naoya Kumagai ◽  
Masakatsu Shibasaki
Keyword(s):  
Asymmetric Synthesis ◽  
Hydroxamic Acid ◽  
Aldol Reaction ◽  
Propargylic Alcohols ◽  
Catalytic Asymmetric Synthesis ◽  
Direct Aldol Reaction ◽  
Catalytic Asymmetric

The catalyst comprising Cu(ii)/chiral hydroxamic acid was found to play a bifunctional role in the direct aldol reaction of α-N3amide to alkynyl CF3ketones.

Sign in / Sign up

Export Citation Format

Share Document