Efficient Synthesis of 3-Substituted 2,3-Dihydroquinolin-4-ones Using a One-Pot Sequential Multi-Catalytic Process: Pd-Catalyzed Allylic Amination—Thiazolium Salt-Catalyzed Stetter Reaction Cascade.

ChemInform ◽  
2006 ◽  
Vol 37 (40) ◽  
Author(s):  
Tetsuhiro Nemoto ◽  
Tomoaki Fukuda ◽  
Yasumasa Hamada
2017 ◽  
Vol 13 ◽  
pp. 1425-1429 ◽  
Author(s):  
Lina Jia ◽  
Fuzhong Han

Background: Phthalides are privileged constituents of numerous pharmaceuticals, natural products and agrochemicals and exhibit several biological and therapeutic activities. Therefore, the development of new, facile, and sustainable strategies for the construction of these moieties is highly desired. Results: A broad substrate scope for β-keto acids was found to be strongly compatible with this catalytic process, affording a wide variety of 3-substituted phthalides in good to excellent yields. Conclusion: A concise and efficient synthesis strategy of 3-substituted phthalides from 2-formylbenzoic acid and β-keto acids via a catalytic one-pot cascade reaction in glycerol has been accomplished.


2013 ◽  
Vol 16 (10) ◽  
pp. 788-790
Author(s):  
Zinatossadat Hossaini ◽  
Samereh Seyfi ◽  
Faramarz Rostami-Charati ◽  
Mehdi Ghambarian

Fuel ◽  
2021 ◽  
pp. 121060
Author(s):  
Chuhua Jia ◽  
Cheng Zhang ◽  
Shaoqu Xie ◽  
Wanli Zhang ◽  
Ziling Wang ◽  
...  

Synlett ◽  
2017 ◽  
Vol 28 (17) ◽  
pp. 2295-2298
Author(s):  
Kommula Dileep ◽  
M. Murty

A simple and efficient synthetic protocol has been developed involving a one-pot three-component reaction of a 2-chlorobenzazole, piperazine, and an arenesulfonyl chloride under aqueous conditions at room temperature in the absence of a catalyst, ligand, or base. By using this protocol, a variety of 2-[4-(arylsulfonyl)piperazin-1-yl]-1,3-benzothiazole, -1H-benzimidazole, and -1,3-benzoxazole derivatives were synthesized in excellent yields.


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