Citridones, New Potentiators of Antifungal Miconazole Activity, Produced by Penicillium sp. FKI-1938. Part 1. Taxonomy, Fermentation, Isolation and Biological Properties.

ChemInform ◽  
2005 ◽  
Vol 36 (47) ◽  
Author(s):  
Takashi Fukuda ◽  
Yuichi Yamaguchi ◽  
Rokuro Masuma ◽  
Hiroshi Tomoda ◽  
Satoshi Omura
2000 ◽  
Vol 53 (11) ◽  
pp. 1247-1251 ◽  
Author(s):  
NORIHIRO KAKINUMA ◽  
HIROKI IWAI ◽  
SENJI TAKAHASHI ◽  
KUNIKATSU HAMANO ◽  
TADASHI YANAGISAWA ◽  
...  

1988 ◽  
Vol 41 (12) ◽  
pp. 1769-1773 ◽  
Author(s):  
SATOSHI OMURA ◽  
HIROSHI TOMODA ◽  
KEIKO KIMURA ◽  
D.-Z. ZHENT ◽  
HIDETOSHI KUMAGAI ◽  
...  

1993 ◽  
Vol 46 (12) ◽  
pp. 1849-1853 ◽  
Author(s):  
NORIKO TABATA ◽  
HIROSHI TOMODA ◽  
ROKURO MASUMA ◽  
KATSUJI HANEDA ◽  
YUZURU IWAI ◽  
...  

Author(s):  
David A. Agard ◽  
Yasushi Hiraoka ◽  
John W. Sedat

In an effort to understand the complex relationship between structure and biological function within the nucleus, we have embarked on a program to examine the three-dimensional structure and organization of Drosophila melanogaster embryonic chromosomes. Our overall goal is to determine how DNA and proteins are organized into complex and highly dynamic structures (chromosomes) and how these chromosomes are arranged in three dimensional space within the cell nucleus. Futher, we hope to be able to correlate structual data with such fundamental biological properties as stage in the mitotic cell cycle, developmental state and transcription at specific gene loci.Towards this end, we have been developing methodologies for the three-dimensional analysis of non-crystalline biological specimens using optical and electron microscopy. We feel that the combination of these two complementary techniques allows an unprecedented look at the structural organization of cellular components ranging in size from 100A to 100 microns.


2015 ◽  
Vol 57 ◽  
pp. 177-187 ◽  
Author(s):  
Jennifer N. Byrum ◽  
William Rodgers

Since the inception of the fluid mosaic model, cell membranes have come to be recognized as heterogeneous structures composed of discrete protein and lipid domains of various dimensions and biological functions. The structural and biological properties of membrane domains are represented by CDM (cholesterol-dependent membrane) domains, frequently referred to as membrane ‘rafts’. Biological functions attributed to CDMs include signal transduction. In T-cells, CDMs function in the regulation of the Src family kinase Lck (p56lck) by sequestering Lck from its activator CD45. Despite evidence of discrete CDM domains with specific functions, the mechanism by which they form and are maintained within a fluid and dynamic lipid bilayer is not completely understood. In the present chapter, we discuss recent advances showing that the actomyosin cytoskeleton has an integral role in the formation of CDM domains. Using Lck as a model, we also discuss recent findings regarding cytoskeleton-dependent CDM domain functions in protein regulation.


Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
A Aly ◽  
R Edrada-Ebel ◽  
V Wray ◽  
P Proksch
Keyword(s):  

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