Microwave-Assisted Direct Synthesis of 2-Substituted Benzoxazoles from Carboxylic Acids under Catalyst and Solvent-Free Conditions.

ChemInform ◽  
2005 ◽  
Vol 36 (41) ◽  
Author(s):  
Raj Kumar ◽  
C. Selvam ◽  
Gurmeet Kaur ◽  
Asit K. Chakraborti
Keyword(s):  
Carboxylic Acids ◽  
Direct Synthesis ◽  
Solvent Free ◽  
Microwave Assisted ◽  
Solvent Free Conditions

scholarly journals Microwave-Assisted Catalytic Method for a Green Synthesis of Amides Directly from Amines and Carboxylic Acids

Molecules ◽  
2020 ◽  
Vol 25 (8) ◽  
pp. 1761 ◽  
Author(s):  
Adam P. Zarecki ◽  
Jacek L. Kolanowski ◽  
Wojciech T. Markiewicz
Keyword(s):  
Carboxylic Acids ◽  
Direct Synthesis ◽  
Solvent Free ◽  
Amide Bond ◽  
Ceric Ammonium Nitrate ◽  
Secondary Amines ◽  
Primary Amines ◽  
Catalytic Method ◽  
Effective Manner ◽  
Solvent Free Conditions

Amide bonds are among the most interesting and abundant molecules of life and products of the chemical pharmaceutical industry. In this work, we describe a method of the direct synthesis of amides from carboxylic acids and amines under solvent-free conditions using minute quantities of ceric ammonium nitrate (CAN) as a catalyst. The reactions are carried out in an open microwave reactor and allow the corresponding amides to be obtained in a fast and effective manner when compared to other procedures of the direct synthesis of amides from acids and amines reported so far in the literature. The amide product isolation procedure is simple, environmentally friendly, and is performed with no need for chromatographic purification of secondary amides due to high yields. In this report, primary amines were used in most examples. However, the developed procedure seems to be applicable for secondary amines as well. The methodology produces a limited amount of wastes, and a catalyst can be easily separated. This highly efficient, robust, rapid, solvent-free, and additional reagent-free method provides a major advancement in the development of an ideal green protocol for amide bond formation.

Microwave-Assisted Efficient, One-Pot, Three-Component Synthesis of 3,5-Disubstituted 1,2,4-Oxadiazoles under Solvent-Free Conditions.

ChemInform ◽  
2006 ◽  
Vol 37 (32) ◽  
Author(s):  
Mehdi Adib ◽  
Amin Haghighat Jahromi ◽  
Narjes Tavoosi ◽  
Mohammad Mahdavi ◽  
Hamid Reza Bijanzadeh
Keyword(s):  
Solvent Free ◽  
One Pot ◽  
Microwave Assisted ◽  
Solvent Free Conditions

Solvent-free, l -Leucine-Catalyzed Direct Dehydrative Esterification of Carboxylic Acids with Alcohols: Direct Synthesis of 3-Alkoxy 1(3 H )-isobenzofuranone

2017 ◽  
Vol 7 (1) ◽  
pp. 227-231 ◽  
Author(s):  
Manoranjan Kumar ◽  
Krishna Thakur ◽  
Sushila Sharma ◽  
Onkar S. Nayal ◽  
Neeraj Kumar ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Direct Synthesis ◽  
Solvent Free

Solid-state regioselective nitration of activated hydroxyaromatics and hydroxycoumarins with cerium (IV) ammonium nitrate

2005 ◽  
Vol 2005 (11) ◽  
pp. 733-735 ◽  
Author(s):  
Nemai C. Ganguly ◽  
Sanjoy Dutta ◽  
Mrityunjoy Datta ◽  
Prithwiraj De
Keyword(s):  
Solid State ◽  
Ammonium Nitrate ◽  
High Efficiency ◽  
Solvent Free ◽  
High Melting ◽  
Microwave Assisted ◽  
Solvent Free Conditions ◽  
High Yields ◽  
Regioselective Nitration ◽  
Cerium Iv Ammonium Nitrate

Predominant ortho-selective mononitration of low-melting and liquid phenols and hydroxycoumarins in moderate to high yields has been accomplished upon grinding with solid cerium (IV) ammonium nitrate (CAN). Microwave-assisted expeditious CAN-mediated nitration of relatively high melting phenols and hydroxycoumarins with high efficiency and selectively under solvent-free conditions has been also developed to address the problems of sluggishness and low yield for these reluctant substrates.

Microwave-assisted synthesis of quinolones and 4H-1,4-benzo thiazine 1,1-dioxides

2005 ◽  
Vol 2005 (1) ◽  
pp. 27-28 ◽  
Author(s):  
Jaime Charris ◽  
Arthur Barazarte ◽  
José Domínguez ◽  
Neira Gamboa
Keyword(s):  
Microwave Irradiation ◽  
Rapid Method ◽  
Solvent Free ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted ◽  
Solvent Free Conditions

A rapid method for the preparation of N-aryl-2-methylthio-4-oxo-1,4-dihydro quinoline-3-carbonitriles (2a–e) and N-aryl-3-methylthio-4H-1,4-benzothiazine-2-carbonitrile 1,1-dioxides (2f–o) is reported. The cyclization is accelerated by microwave irradiation under solvent free conditions in the presence of K2CO3.

scholarly journals Microwave-assisted synthesis under solvent-free conditions of (E)-2-(Benzo[d]thiazol-2-yl)-3-arylacrylonitriles

2011 ◽  
Vol 22 (12) ◽  
pp. 2396-2402 ◽  
Author(s):  
Jorge E. Trilleras ◽  
Kelly J. Velasquez ◽  
Dency J. Pacheco ◽  
Jairo Quiroga ◽  
Alejandro Ortíz
Keyword(s):  
Solvent Free ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted ◽  
Solvent Free Conditions
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