Carbon Dioxide Promoted Palladium-Catalyzed Cyclotrimerization of Alkynes in Water.

ChemInform ◽  
2004 ◽  
Vol 35 (38) ◽  
Author(s):  
Jin-Heng Li ◽  
Ye-Xiang Xie
Keyword(s):  
Carbon Dioxide ◽  
Palladium Catalyzed

Carbon Dioxide-Driven Palladium-Catalyzed C–H Activation of Amines: A Unified Approach for the Arylation of Aliphatic and Aromatic Primary and Secondary Amines

Synlett ◽  
2019 ◽  
Vol 30 (05) ◽  
pp. 519-524 ◽  
Author(s):  
Michael Young ◽  
Mohit Kapoor ◽  
Pratibha Chand-Thakuri ◽  
Justin Maxwell ◽  
Daniel Liu ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Bond Activation ◽  
Secondary Amines ◽  
Activation Process ◽  
Unified Approach ◽  
Benzylic Amines ◽  
Palladium Catalyzed ◽  
Group A ◽  
Directing Group ◽  
Site Selective

Amines are an important class of compounds in organic chemistry and serve as an important motif in various industries, including pharmaceuticals, agrochemicals, and biotechnology. Several methods have been developed for the C–H functionalization of amines using various directing groups, but functionalization of free amines remains a challenge. Here, we discuss our recently developed carbon dioxide driven highly site-selective γ-arylation of alkyl- and benzylic amines via a palladium-catalyzed C–H bond-activation process. By using carbon dioxide as an inexpensive, sustainable, and transient directing group, a wide variety of amines were arylated at either γ-sp3 or sp2 carbon–hydrogen bonds with high selectivity based on substrate and conditions. This newly developed strategy provides straightforward access to important scaffolds in organic and medicinal chemistry without the need for any expensive directing groups.1 Introduction2 C(sp3)–H Arylation of Aliphatic Amines3 C(sp2)–H Arylation of Benzylamines4 Mechanistic Questions5 Future Outlook

Palladium-catalyzed synthesis of symmetrical urea derivatives by oxidative carbonylation of primary amines in carbon dioxide medium

2011 ◽  
Vol 282 (1) ◽  
pp. 120-127 ◽  
Author(s):  
Nicola Della Ca’ ◽  
Paolo Bottarelli ◽  
Angela Dibenedetto ◽  
Michele Aresta ◽  
Bartolo Gabriele ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Primary Amines ◽  
Oxidative Carbonylation ◽  
Urea Derivatives ◽  
Palladium Catalyzed

Palladium-catalyzed oxidation of geraniol in dense carbon dioxide

2006 ◽  
Vol 299 ◽  
pp. 66-72 ◽  
Author(s):  
Marco Burgener ◽  
Tomasz Tyszewski ◽  
Davide Ferri ◽  
Tamas Mallat ◽  
Alfons Baiker
Keyword(s):  
Carbon Dioxide ◽  
Dense Carbon Dioxide ◽  
Palladium Catalyzed ◽  
Catalyzed Oxidation

ChemInform Abstract: Palladium-Catalyzed Cross-Coupling Reactions in Supercritical Carbon Dioxide.

ChemInform ◽  
2010 ◽  
Vol 33 (6) ◽  
pp. no-no
Author(s):  
Tessa R. Early ◽  
Richard S. Gordon ◽  
Michael A. Carroll ◽  
Andrew B. Holmes ◽  
Richard E. Shute ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Carbon Dioxide ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Cross Coupling Reactions ◽  
Palladium Catalyzed ◽  
Supercritical Carbon

Palladium-Catalyzed [3+2] Cycloaddition of Carbon Dioxide and Trimethylenemethane under Mild Conditions

2007 ◽  
Vol 9 (19) ◽  
pp. 3817-3820 ◽  
Author(s):  
George E. Greco ◽  
Brittany L. Gleason ◽  
Tiffany A. Lowery ◽  
Matthew J. Kier ◽  
Lisa B. Hollander ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Mild Conditions ◽  
Palladium Catalyzed
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