Synthetic Studies on Ecteinascidin 743: Rapid Access to the Fully Functionalized Tetrahydroisoquinoline with a Bridged 10-Membered Sulfur Containing Macrocycle.

ChemInform ◽  
2004 ◽  
Vol 35 (13) ◽  
Author(s):  
Michael De Paolis ◽  
Angele Chiaroni ◽  
Jieping Zhu
1991 ◽  
Vol 32 (33) ◽  
pp. 4151-4154 ◽  
Author(s):  
Shigeru Nishiyama ◽  
Ji-Fei Cheng ◽  
Xue Liang Tao ◽  
Shosuke Yamamura

2001 ◽  
Vol 79 (11) ◽  
pp. 1632-1654 ◽  
Author(s):  
Richard R Hark ◽  
Diane B Hauze ◽  
Olga Petrovskaia ◽  
Madeleine M Joullié

Ninhydrin is an essential tool in the analysis of amino acids, peptides, and proteins, and the preferred reagent for the detection of latent fingerprints on porous surfaces. The goal of this investigation was to prepare ninhydrin analogs with enhanced chromogenic and fluorogenic properties. Target compounds included structures with extended conjugation and (or) with the presence of sulfur-containing moieties. We have devised general convergent routes for novel heterocyclic and aryl-substituted ninhydrin analogs for use as reagents for amino acid detection.Key words: ninhydrin analogs, synthesis, ketals, Suzuki cross-coupling reactions, Stille cross-coupling reactions.


2017 ◽  
Vol 15 (25) ◽  
pp. 5258-5262 ◽  
Author(s):  
Kai Sun ◽  
Yunhe Lv ◽  
Zuodong Shi ◽  
Shiqiang Mu ◽  
Changhao Li ◽  
...  

A rapid access to β-azolyl sulfides has been developed for the synthesis of nitrogen- and sulfur-containing molecules.


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